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Tag: "candidate" at biology news

Genomic Analysis Uncovers New Targets for HIV Vaccine

...tein said. "Past studies have looked at individual candidate genes. Since different people respond differently to infections, a better understanding of how immune system genes control responses to infections should help us to design better treatments and more effective vaccines." Added Haynes: "CHAVI was desi...

Massive herds of animals found to still exist in Southern Sudan

...ogram; and Malik Marjan, a Southern Sudanese Ph.D. candidate from the University of Massachusetts, Amherst. They worked in cooperation with the Ministry of the Environment, Wildlife Conservation, and Tourism of the Government of Southern Sudan (GoSS). Funding for the project also came from USAID under the USAI...

New Brandeis research sheds light on memory by erasing it

...tem for studying memory. CaMKII has been a leading candidate as a memory molecule because it is persistently activated after LTP induction and can enhance synaptic transmission, properties that are necessary for a memory molecule. Like a computer whose electronics change with the addition of new information...

Molecule that destroys bone also protects it, new research shows

...hor. Jeffrey J. Yu, a medical student and doctoral candidate who is a researcher working in Gaffen’s lab, is fi...given systemically, so it may not be a therapeutic candidate to increase immunity. But inhibitors of IL-17 are considered important targets for drugs to treat au...

LIAI scientists make important finding on cytomegalovirus transmission

...ommunity should be looking at IL-10 as a molecular candidate that might be used to control persistent viral infections." Ware and Croft’s next step will be conducting animal studies with the IL-10 suppression and the OX40 enhancement combined into one treatment. "We tested them separately, but they may wel...

Peanut allergies overstated, study finds

..., a Sydney Children's Hospital immunologist and MD candidate at UNSW. "Because peanut allergies are potentially serious, requiring all sorts of restrictions, families can become very anxious when in fact, some of these families may be worrying unnecessarily," Dr Wainstein said. The study, published in th...

Discovery of 'master switch' for the communication process between chloroplast and nuclei of plants

...tions in the paper is that ABI4 seems like a prime candidate to be the ‘master switch,? Koussevitzky said. "ABI4 binds to a newly identified sequence motif, and by doing so prevents light-induced regulatory factors from activating gene expression. It has a role in so many signaling processes in the plant, it m...

30+ AIDS vaccine clinical trials in 24 countries, research occurring on every continent

...d to evaluate the safety and immunogenicity of the candidate vaccines. "Although these new trials are early-sta...t-of-concept trial with its adeno-5 vector vaccine candidate is expected in 2008 or 2009 and will provide preliminary information on the efficacy of this type of...

LIAI completes world's most comprehensive analysis on influenza virus data

...t has been published, which appears to be an ideal candidate for creating a multi-strain influenza vaccine. Regarding gaps in knowledge of the way people respond to influenza, Wilson said two significant points emerged. "One concern is that most of the current influenza research is based on strains maintain...

Africa's first large-scale HIV vaccine study launches

...aunch of the first large-scale study to evaluate a candidate HIV vaccine on the African continent was announced today by study collaborators in the United States and South Africa. The trial will involve up to 3,000 participants at five sites throughout South Africa and is expected to continue for four years. ...

NASA predicts nongreen plants on other planets

...green plants. "We can identify the strongest candidate wavelengths of light for the dominant color of photosynthesis on another planet," said Nancy Kiang, lead author of the study and a biometeorologist at NASA's Goddard Institute for Space Studies, New York. Kiang worked with a team of scientists from t...

Gene elevating breast cancer risk also causes prostate cancer

...a potential heritable breast cancer susceptibility candidate by screening for disease-related alterations. The results of this international research effort were recently published in Nature. The research first involved comprehensive screening for genetic aberrations in 113 Finnish breast cancer families. T...

Trusting your instincts leads you to the right answer

...part of cognition engages and examines whether the candidate really is the target or not. If the target is not distinctive enough in the 'eyes' of the conscious, failure of identification can occur." ...

Novel antigen-cloning technique may boost efforts to develop a melanoma vaccine

...n discovered in her lab, RPL8, is an ideal vaccine candidate because it has the potential for eliciting both helper T cells and CTL responses, Herlyn says. RPL8 is a protein involved in protein synthesis and is also expressed in normal cells. Herlyn's study shows that RPL8 is over-expressed not only in melanom...

Putting an old drug to a new use

...sbruck. "These effects make nifedipine a promising candidate for a new drug to treat hereditary hemochromatosis and other iron overload disorders." Combining electrophysiology, cell biology and molecular investigations, Weiss and his collaborators found out that nifedipine exerts its effect on iron metaboli...

New cell type identified in cancer development

...gs, if validated by additional studies, point to a candidate population of precancerous cells that may one day be a valuable target for new drugs and treatments. "To cure cancer, we have to eliminate all potential malignant cells ?not just the ones within easy reach." ...

Cancer vaccines -- Taking a jab at cancer by stimulating the immune system

...in women vaccinated with the HPV-16/18 L1 VLP AS04 candidate vaccine: Abstract 4900 Ongoing evaluation of a phase II trial of a human papillomavirus vaccine, developed to prevent cervical cancer, shows that the vaccine continues to protect against HPV types 16 and 18 at five and a half years into the study...

Genes and biomarkers that allow doctors to choose the right therapy for the right patient

...TGen. "In this study, we were able to discover new candidate gene states that may be useful in determining a pa...eral sensitizing drug targets that reveal a set of candidate combination drugs that are predicted to be synergistic with Tykerb." Tykerb is an enzyme inhibi...

Natural gut hormone offers hope for new obesity drug

...ion to appetite suppression and is the most likely candidate for translating into a treatment. "Developing a treatment based on natural appetite suppression, mimicking our body's response to being full, has the potential to be safe and effective," says Professor Bloom. "We believe that pancreatic polypeptid...

New synthetic self-assembling macromolecules mimic nature

...f chemistry at Virginia Tech, and Min Mao, a Ph.D. candidate in polymer chemistry, report the synthesis of a new family of charged, rod-like block copolymers. Only as long as a fraction of the diameter of human hair, the tiny rods can be either positive or negative, or can have alternating positive and negati...

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