Researchers discover why melanoma is so malignant
...with its metastatic engines fully revved. "Other cancers need to learn how to spread, but not melanoma," sa...d gain the ability to spread--something that other cancers can spend decades trying to do. Weinberg's team demonstrated this through a number of experiments....Building a better mouse model of lung cancer: FHIT counts
... neck, esophageal, colorectal, breast and cervical cancers as well. Because the loss of FHIT occurs so early in lung cancer, mice that are missing that gene may be a good model in which to test new ways to treat or prevent the disease, says Huebner. "There are some other useful mouse models out there, but t...Chernobyl: The true scale of the accident
...veness, since the incidence of spontaneous thyroid cancers is increasing significantly as the target populati...ery operation workers, some increase in particular cancers (e.g., leukemia) has already been observed. Confusion about the impact has arisen owing to the fact...Customized gene chip provides rapid detection of genetic changes in children's cancer
...rect risk level allows doctors to treat aggressive cancers appropriately, while not subjecting children with low-risk cancer to overtreatment. Cancer researchers have pinpointed specific genetic abnormalities that influence the aggressiveness of neuroblastoma. An important abnormality is loss of heterozygos...Researcher uncovers details of how cancer spreads
... v-Src in human cancer patients, a number of other cancers have been linked to viruses, including the herpes virus and its association with cervical cancer. "Critics of this work will ask why v-Src has not been found in human cancer," said Guan. "But there are many examples of studies and ideas that come ou...Study hints at role of stem cell genes in testicular, breast cancers
...nding might lead to information about where breast cancers come from," Clark adds. "Are they derived from an ...that embryonic stem cell genes play a role in some cancers is not surprising. Embryonic stem cells, which emerge in the first five to seven days of the embryo'...Scientists closer to new cancer detection method
... to a technique to easily detect a wide variety of cancers before symptoms become apparent. The findings, currently online in the Proceedings of the National Academy of Sciences, involve introducing molecularly engineered strands of DNA into cell cultures and observing whether they unleash a fluorescent bur...Biologists Crack Genetic Code for Specialized Spider Silk
...ith CVID also have an increased risk of developing cancers that affect B cells, cells that produce antibodies. Furthermore, IgA deficiency and CVID can predispose to autoimmune diseases, where the immune system turns against the body’s own tissues and organs. “Most cases of CVID and IgA deficiency are of un...Agreement will speed research on microbicides for women
...ith CVID also have an increased risk of developing cancers that affect B cells, cells that produce antibodies. Furthermore, IgA deficiency and CVID can predispose to autoimmune diseases, where the immune system turns against the body’s own tissues and organs. “Most cases of CVID and IgA deficiency are of un...Defective Gene Linked to Two Inherited Immune Deficiencies
...ith CVID also have an increased risk of developing cancers that affect B cells, cells that produce antibodies. Furthermore, IgA deficiency and CVID can predispose to autoimmune diseases, where the immune system turns against the body’s own tissues and organs. “Most cases of CVID and IgA deficiency are of un......tion between factors such as Ets-1 and a number of cancers prompted the study of how it works. One way proteins are controlled occurs after a cell creates a protein. Graves illustrates this process by comparing protein structure with beads on a string. "After the protein is made, it can acquire what we call...Updated data on novel HPV vaccine confirms efficacy in large population
...ntraepithelial neoplasia) or non-invasive cervical cancers associated with human papillomavirus (HPV) types 1... types 16 and 18, is the primary cause of cervical cancers and other related illnesses, infecting more than 20 million Americans. Globally, cervical cancer is...UT Southwestern researchers discover master switch in cell death
...when it works right, but malignant in a variety of cancers when it malfunctions. The researchers are now exa...r side of this complex process manifests itself in cancers when cells don’t die when they’re supposed to. The key to the researchers?finding was the interacti...Discarded placentas deliver researchers promising cells similar to embryonic stem cells
...ession, because telomerase is associated with many cancers and one of the main concerns about stem cell therapies is that transplanted stem cells would replicate in the recipient to form tumors," noted Toshio Miki, M.D., Ph.D., first author of the paper and an instructor in the department of pathology at the...Neurotransmitters signal aggressive cancer, offer potential for early diagnosis
...de aggressive types of lung, thyroid, and prostate cancers that spread to other parts of the body. Their stud... provide new ways to diagnose these poor prognosis cancers earlier and to implement more effective treatments" Gordon says. The researchers believe that metas...Eleven gene 'signature' reliably predicts cancer prognosis
...ay that exists in a very malignant subset of human cancers predicts a marked predisposition toward metastasis and a high probability of poor therapy outcome. In an accompanying commentary, Gordon Mills and others write, "such a "magic marker" [will] have a major impact on patient care." TITLE: Microarray an...Breast tumors in mice eradicated using cancer vaccine
...is overexpressed in 20 to 40 percent of all breast cancers and also present in many cancers of the ovaries, lung, pancreas, and gastrointestinal tract. These cells eventually enlist killer T c...Forsyth scientists find three bacteria associated with oral cancer
...ous cell carcinoma (OSCC)--one of the deadliest of cancers because it often goes undetected in its early stag... the relationship of oral bacteria to a variety of cancers and diseases. According to Goodson, "This research is important for the questions it raises. Do ora...Researchers discover how tumor suppressor gene works
...resses the development of melanoma and other human cancers works. The study points the way to treatments base...ent in the development of melanoma and other human cancers is the inactivation of a gene known as "p16." Normally, p16 keeps cells from growing rapidly, a cond......us, which was administered to mice with pancreatic cancers at both primary and distant sites (akin to metastases). As predicted, when the virus was injected directly into the primary tumor, the virus destroyed not only the primary tumor, but also distant tumors. While the infection caused by the virus was ...