cancers 2 8

Tag: "cancers" at biology news

Preclinical study of a new brain tumor therapy

...ed EGFR. The treatment could eliminate established cancers and there was no evidence of recurrence: the mice remained cancer free for over a year. It is more difficult to cure cancer in humans than cancer in mice, but the results are encouraging. In his Perspective article accompanying the study, Robert Weil...

Sensors, a smart dose of medicine for cancer treatment

...diotherapy (IMRT). IMRT is a radiation therapy for cancers that improves clinical outcomes by more accurately targeting tumours and minimising the amount of radiation absorbed by healthy tissue. The result is that patients only receive a high radiation dose where they need it and healthy tissue is preserved...

Study shows combination of immune substances to be safe

...with different types of advanced cancer, including cancers of the colon, lung, kidney and bladder and melanoma. On the first day of treatment, patients were given IL-12, initially by injection and then intravenously. That was followed by injections of interferon over the next five days. On average, patient...

NIH launches comprehensive effort to explore cancer genomics

... project. The process for determining the types of cancers to be studied is currently underway. Cancer is no...o breast cancer, colon cancer, melanoma, and other cancers already have led to diagnostic tests that can point to the most effective intervention. Recent disco...

Researchers discover new form of cancer gene regulation

...nes result in severe birth defects and devastating cancers in humans. "While some cancers are explained by known defects in the regulation of the GLI1 gene, for many cancers the reasons for ...

UCLA discovery will aid in treatment of patients with a deadly brain cancer

...lockers. Previous UCLA research in brain and other cancers suggested that the key might be the interaction of...e important implications in other cancers. "Many cancers have a similar combination of a mutant cancer-causing protein and either the expression or loss of t...

Gene variation affects tamoxifen's benefit for breast cancer

...p breast cancer. Approximately 70 percent of these cancers are fueled by estrogen, many of which are treated with tamoxifen, a drug designed to block the effects of estrogen in breast tissue. The findings from this trial were derived from a large North Central Cancer Treatment Group study in which women were...

Cancer support cells may evolve, fuel tumor growth, study shows

...ntists have demonstrated in a living organism that cancers may cause surrounding supportive cells to evolve and ultimately promote cancer growth. The new research offers what is believed to be the first evidence that mutations within cancer cells can signal surrounding tissue cells to alter their molecular ...

Harnessing genomic research

... Personalised cancer treatment- A large number of cancers are linked to mutations in a specific gene or biol... from the loss of specific gene function in breast cancers that will correlate with susceptibility to a new anti-cancer drug being developed by KuDOS. The drug...

New view of cancer: 'Epigenetic' changes come before mutations

...online Dec. 21, he and his colleagues suggest that cancers instead begin with "epigenetic" alterations to st...ned off. Feinberg and his colleagues propose that cancers develop via a three-step process. First, there is an epigenetic disruption of progenitor cells withi...

New technique multiplies life span in simple organisms

...he possibility that the mutations that cause human cancers can be delayed or prevented," Longo said. "Notably, mutations that increase the activity of human homologs of the yeast SCH9 and RAS2 genes play central roles in many human cancers." Homologs are genes descended from a common ancestral DNA sequence....

Bacterial protein mimics host to cripple defenses

... helps organisms contain infections, nip potential cancers in the bud, and get rid of old or unneeded cells. However, runaway PCD leads to everything from unseemly spots on tomatoes to Parkinson's and Alzheimer's diseases. BTI Scientist and Cornell University Professor of Plant Pathology Gregory Martin stud...

FSU biologists describe key role of signal-transcribing gene during cell cycle

... 'Development' shows when, where Alzheimer's, some cancers and genetic ills beginT. Biologists at Florida State University have uncovered the pivotal role of a gene called "Cut" that acts as a sort of middleman in cell-to-cell communication. A DNA-binding protein, Cut interprets and transcribes the developm...

Nanoparticles, nanoshells, nanotubes: How tiny specks may provide powerful tools against cancer

...dump nanoshells into tumors, it cannot "find" tiny cancers that have metastasized and have not yet "recruited... vectors aren't reliable." More than one-half of cancers have mutations in the p53 gene, which has been called the "guardian of the genome" because of its ab...

Double trouble: Cells with duplicate genomes can trigger tumors

...-value" cells are seen in a variety of early human cancers and in a precancerous condition called Barrett's esophagus. In addition to the extra chromosomes, the "double value" or "tetraploid" cells also duplicate a cell structure called the centrosome that plays a role in maintaining a stable genome. The ext...

University of Delaware researchers develop cancer 'nanobomb'

...ancerous cells are often left behind. In addition, cancers in some part of the body, such as arteries and veins, are sometimes considered inoperable. Nanobombs can be used to target any remaining cancerous cells and can be used in any part of the body, allowing the creation of nanobomb therapy for a wide var...

War on terror meets war on cancer

... may have some new uses: detecting rapidly growing cancers and studying obesity and eating disorders. The method, known as "stable isotope ratio mass spectrometry," can determine where a substance was produced by "weighing" various forms or isotopes of an element in the substance ?such as the ratio of rare...

Mechanism for Epstein-Barr virus protein's role in blood cancers discovered

... of the most common human viruses, plays a role in cancers such as lymphoproliferative diseases in transplant or AIDS patients, Burkitt's lymphoma, Hodgkin's lymphoma, and nasopharyngeal carcinoma, and also causes the well-known disease infectious mononucleosis. As many as 95 percent of adults 20 years and o...

Restoring silenced suppressor gene kills lung-cancer cells

...lenced in a large majority of lung cancers, and in cancers of the breast, ovary, prostate, bladder, esophagus and pancreas. The work was led by scientists at The Ohio State University Comprehensive Cancer Center ? Arthur G. James Cancer Hospital and Richard J. Solove Research Institute. The study showed th...

Einstein scientists discover how protein crucial for motion is synthesised at the right place in the cell

...ld force tumor cells to express ZBP1 might prevent cancers from spreading." In addition to Dr. Singer, other Einstein researchers involved in the study are Dr. John Condeelis, professor and co-chair with Dr. Singer of Einstein's Department of Anatomy and Structural Biology, Daniel Zenklusen, Mike Lorenz, Xi...

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