cancers 2 6

Tag: "cancers" at biology news

Malignant melanoma cells secrete protein required for embryo formation

...rovides a novel target for treatment of aggressive cancers such as melanomas," said Mary J. C. Hendrix, the corresponding author, of Children's Memorial Research Center where the discovery was made. Hendrix is president and scientific director of the Children's Memorial Research Center, professor of pedia...

New human retrovirus originated in mice

... The initial screen of the RNASEL-mutant prostate cancers revealed the presence of a genetic sequence that c... Importantly, the researchers found that prostate cancers in which both copies of the RNASEL gene were crippled by mutation showed much more frequent XMRV inf...

Scientists uncover rules for gene amplification

...e amplification plays an important role in causing cancers via activation of oncogenes. If scientists can determine the rules as to which segments of genetic material become amplified and how, oncologists and drug researchers may be able to interrupt that process and prevent the formation and growth of some ...

Mayo Clinic study finds two genes predict outcome for breast cancer patients

...United States. More than two-thirds of all breast cancers are hormone positive, and most of these are early stage (lymph node-negative). ...

New device could cut chemotherapy deaths

... extensive research experience in gastrointestinal cancers and stem cells in the gastrointestinal tract. Dr Perera has also been working with the University's Department of Pharmacy & Pharmacology to make the fibres more sterile so they cannot be attacked by harmful bacteria. Dr Perera said that other ...

Mayo Clinic researchers discover cancer cells may move via wave stimulation

...a new cellular secret that may explain how certain cancers move and spread -- a feature of cancers that makes treatment especially difficult. If the mechanism that drives cancer movement -- also call...

Inflammation and drugs to control this activity studied in a variety of tumors sites

...ofen. The AMACR protein is overexpressed in some cancers such as prostate, colon and precancerous colorectal adenomas, or polyps, though it is expressed very little in normal tissues. According to Daugherty, no one had examined the association between AMACR variants and colorectal adenomas or cancer. The ...

Mutation in blood stem cells provides clues to cancer development

... and tissues, and those are the same pathways that cancers use, subverting normal processes and using them for the wrong purpose. The discovery of this mutation means we can look toward interrupting these pathways, systematically, without wiping out the patient's normal blood cells." PV is diagnosed in ap...

Common molecular 'signature' identified in solid tumors

...s have discovered that a wide variety of different cancers actually share something in common ?a molecular "s...g miRNAs were deregulated in at least three of the cancers ?and in some cases, as many as five or all six. The researchers defined this limited set as the "miR...

Study may help slay 'Yellow Monster'

...eted uranium and Gulf War Syndrome or to increased cancers and birth defects in the Middle East. Stearns said it is estimated that more than 300 tons of depleted uranium were used during the first Gulf War. Military uses of depleted uranium in weapons continue today. Closer to home, questions continue to be...

Molecular force field helps cancer cells defend against attack

...ull FAK out of human tumors and to show that human cancers make the molecule in large quantities. In 1996, th...-3 in cell cultures of human breast cancer. Breast cancers that pump out high volumes of FAK and VEGFR-3 are more aggressive tumors, Cance said. The scientists...

Statins have neutral effect on risk of cancer

...the authors report. "No reductions were noted for cancers of the breast, colon, gastrointestinal tract, prostate, respiratory tract, or skin (melanoma) when statins were used." The authors continue, "?the patients in our meta-analysis were primarily treated with simvastatin and pravastatin. As such, we e...

Loosen leash on cancer protein 'watchdog,' researchers say

...rotein "watchdog" on high alert to stop hereditary cancers from overrunning our bodies - if they can keep it on a leash of just the right length. In a collaborative effort, a team of scientists including Purdue University's Susan M. Mendrysa has found that one of the proteins found naturally in cells has th...

'Shuttling' protein possibly key to resilience of cancer cells

...e development of innovative treatments for certain cancers and other conditions," said Chang-Deng Hu, an assistant professor in Purdue's Department of Medicinal Chemistry and Molecular Pharmacology and an investigator at the Walther Cancer Institute in Indianapolis. The experiments were done using a line of...

Can dogs smell cancer?

In a society where lung and breast cancers are leading causes of cancer death worldwide, earl...ple with both early and late stage lung and breast cancers from healthy controls. The research, which was performed in California, was recently documented by t...

New test to detect rare proteins in blood

...discerning low-abundance molecules associated with cancers (such as breast cancer), Alzheimer's disease, prion diseases, and possibly psychiatric diseases relatively easy and more accurate compared with the current methodology, including the widely used ELISA (enzyme-linked immunoadsorbent assay). ELISA is...

UCLA scientists uncover mechanism of response to targeted therapy

..., which cuts off the independent blood supply that cancers need to grow and flourish. The CCI-779 would stop the growth of the cancer, and the chemotherapy would be used to kill the cancer cells or the angiogenesis inhibitor could be administered to cut off the blood supply to the tumor, stopping the flow of...

HPV subtype associated with squamous cell skin cancers

... HPV 16, has been associated with other epithelial cancers such as cervical cancer. Genus beta HPVs, which includes HPV types 5 and 8, have been detected in skin tumors, and previous studies suggest they may play a role in the development of these cancers. Margaret R. Karagas, Ph.D., of Dartmouth Medical S...

When good DNA goes bad

...to the kind of genetic instability associated with cancers such as leukemia and lymphoma, according to a study by researchers at The University of Texas M. D. Anderson Cancer Center. The study, issued in advance of the Feb. 21 edition of the Proceedings of the National Academy of Sciences, demonstrates for...

Scientists discover a genetic switch that links animal growth and cancer

...es might similarly be involved in the formation of cancers and could provide new therapeutic targets for intervention in cancer. The current findings took about four years to discover. The worms used in the research develop quickly, growing from an egg to an adult in three days, as compared to mice, for exa...

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