cancers 2 5

Tag: "cancers" at biology news

Scientists tie several cancers to common 'oncogene engine'

... that it may be possible to attack these different cancers with the same therapy. Reporting in the June issu...y cancer that mainly affects children. Still other cancers sharing the same causative mechanism may yet be found, the scientists said. "One would have never t...

Activation of microRNA inhibits cancer gene in human cancer cells

...tion that some miRNAs are reduced in various human cancers and may normally function as tumor suppressors. According to study author Dr. Peter A. Jones from the Norris Comprehensive Cancer Center at the University of Southern California in Los Angeles, "Although the biological importance of miRNA is becoming...

Compound in dairy products targets diabetes

...d in CLA when it was shown to inhibit a variety of cancers such as breast, skin and colon in mice, and further research showed effects on circulating cholesterol and inflammation. These effects are the same as the newest generation of synthetic drugs used to treat diabetes in humans. These synthetic dru...

Researchers unveil strategy for creating actively-programmed anti-cancer molecules

...-a cell membrane protein expressed on a variety of cancers and the vasculatures they produce. "Key to this unique approach is the ability of the small molecule targeting agents-called programming agents or adapters-to selectively react in the antibody binding sites without compromising the targeting proper...

Research links protein to breast-cancer migration

...ulty of Life Sciences. "But metastases ?malignant cancers that spread to other parts of the body ?can be muc...esearch is potentially fundamental to all types of cancers and has the potential to offer alternative therapies to stop cancers spreading to other organs in th...

Unique dual target specificity of kinase inhibitor key for success against cancer

...s a safe and effective therapy in the treatment of cancers driven by aberrant signaling through PI3 kinase," says Dr. Weiss. "Glioma represents the most common primary brain tumor, and there are no curative medical therapies. Ultimately, we believe that PI-103 displays the hallmarks of the most successful ca...

Gene screen for breast cancer better than pathologist's 'eye'

...umar, who believes that their gene screen may miss cancers if they overlook any hidden breast ducts. Improvements in getting an accurate representation of fluid from all the breast ducts are underway by other investigators, and include using sound waves to locate all the ducts. ...

First-ever genomic test predicts which lung cancer patients need chemotherapy to live

...ans each year than breast, prostate and colorectal cancers combined. But toxic chemotherapy drugs are prescribed only to patients with relatively large and aggressive tumors. Early-stage patients ?those with small, stationary tumors ?are considered at low risk of recurrence. Hence, they only receive surger...

Structure determined for p53 tumor suppressor protein as bound to DNA for anti-cancer activity

More than half of human cancers involve mutations in the p53 tumor-suppressor gene, suggesting the critical role played by the normal p53 protein in defending against cancer. Similarly, roughly 95 percent of cancer-causing mutations in the p53 protein occur in its DNA-binding core ...

Gene first linked to rare disease may trigger skin cancer, other tumors

...benign skin tumors may be a more general player in cancers found throughout the body, according to a report i... preliminary analysis of CYLD levels in human skin cancers originating from the epidermis, including basal cell carcinomas (BCC) and squamous cell carcinomas (...

FSU biologists uncover mechanisms that shape cells for better or worse

...ay help to clarify how muscular dystrophy and some cancers develop in humans. That's because many of the genes involved in the cell-to-cell communication that triggers the development of cell polarity in Drosophila oocytes (unfertilized fruit fly eggs) also are known players in the pathogenesis of those di...

'Signature' of chromosome instability predicts cancer outcomes

...ocess breaks down, chromosomes become unstable and cancers are more likely to develop. Chromosomal instab...ant predictor of clinical outcomes in a variety of cancers (breast, lung, medulloblastoma, glioma, mesothelioma and lymphoma). It could also differentiate betw...

Cigarette smoke blocks cell repair mechanism, University of Florida study shows

...wo days or in months; it takes years and years for cancers to develop. Once the gene is damaged and sitting there it's going to provide some harmful effect later on." Jose Russo, M.D., a researcher at the Fox Chase Cancer Center in Philadelphia who has studied how breast epithelial cells transform after ex...

Selenium-protein deficiency raises prostate cancer risk

...n shown in many studies to reduce the incidence of cancers -- notably lung, colorectal and prostate. "The problem is, nobody seems to know how the mechanism works, and that's not trivial," said Alan Diamond, professor of human nutrition at the University of Illinois at Chicago and principal investigator in ...

New lab technique churns out fungus' potential cancer fighter

...that seemed tailor-made to knock out ras-dependent cancers like pancreatic cancer. After six years, however, rasfonin's secrets remain a mystery because researchers can't make enough of it to carry out tests. To bring about a new drug, organic chemists must produce a new chemical in enough quantity to test...

New lab technique churns out fungus' potential cancer fighter

...that seemed tailor-made to knock out ras-dependent cancers like pancreatic cancer. After six years, however, rasfonin's secrets remain a mystery because researchers can't make enough of it to carry out tests. To bring about a new drug, organic chemists must produce a new chemical in enough quantity to test...

A switch between life and death

...nto the central role it plays in tissue growth and cancers in humans and other organisms. ...

Radioactive scorpion venom for fighting cancer

...the cells of a type of essentially incurable brain cancers known as gliomas. Responding to this urgent problem, scientists at the Transmolecular Corporation in Cambridge, Massachusetts created a radioactive version of this scorpion venom. Called TM-601, it contains an artificial version of the venom prote...

New pathways for autoimmune treatment identified

...cytokines. That's why it also has worked for some cancers and why a modified version of the glycolipid or totally different drugs may work better, Dr. She says. "By understanding more, we are better able to come up with better targets," he says. " i NKT development is still the big question," says Dr. Mi....

Speeding discovery of the 'human cancer genome'

...gineered mice, by definition, develop more defined cancers than humans," he said. "Mice can therefore be used...e difficult to treat and deadly. The metastatic cancers of mice developed a chromosomal amplification--a region of the genome expressed in an unusually larg...

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