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Tag: "cancers" at biology news

CSHL research ties harmless viruses to cancer

...sion that they cause may decrease the frequency of cancers and prevent their progression," said CSHL’s lead investigator Yuri Lazebnik. According to this model, cells can be made cancerous by viruses that fuse cells. Fusion abruptly unites two or three cells under the same membrane, a change that triggers m...

Reactivated gene shrinks tumors

Many cancers arise due to defects in genes that normally suppre...of cancer-lymphomas and sarcomas. In lymphomas, or cancers of the white blood cells, the cancer cells underwent apoptosis within 1 or 2 days of the p53 reactiv...

Turning a cellular sentinel into a cancer killer

...taining tumors. While the researchers caution that cancers can mutate to circumvent p53 reactivation, they be... effect." For one thing, the high mutation rate in cancers might enable a cancer to switch the p53 pathway back off, or to circumvent the pathway in some other...

Light-based probe 'sees' early cancers in first tests on human tissue

...according to the researchers. The vast majority of cancers start in the body's epithelial cells, which line t...gs, esophagus and gut. "About 85 percent of all cancers start in the epithelium. It may be, for example, brain cancer that causes a patient's death, but tha...

Chemicals in brown algae may protect against skin cancer

...f brown marine seaweed, might protect against skin cancers caused by ultraviolet B (UVB) radiation. UVB radiation in sunlight is thought responsible for 90 percent of the estimated 1.3 million cases of non-melanoma skin cancer diagnosed in the United States annually. Researchers applied the BAPs to t...

White blood cells of cancer-resistant mice overwhelm natural defenses of cancer cells

...en from these cancer-resistant mice cured advanced cancers in ordinary mice and also protected those normal m...e suggests that there may be some things that most cancers have in common," said Willingham, a pathologist and head of the Section on Tumor Biology. ...

Stress hormones may play new role in speeding up cancer growth

...his suggests a new approach to possibly fight some cancers ?the prescribing of beta-blocker-type drugs that would block these receptors and perhaps slow the progression of the disease," Glaser said. "Using this approach may not cure this cancer but perhaps we could slow down its growth, making the tumor m...

St. Jude announces breakthrough in eye cancer treatment

... important implications for certain forms of adult cancers as well. "Some forms of breast, lung, prostate and...s," Dyer explained. "So knocking out MDMX in those cancers might also dramatically reduce tumor size. And administering the drug directly to the site of the tu...

Signal protein shows promise for blocking tumor promoters in skin cells

...tion. Src kinase activity is elevated in most skin cancers and in common carcinomas, including those of the b...m might play a role in targeted gene therapies for cancers that are triggered by activated Src kinases. Such a therapy would likely use an adenovirus to carry...

Molecular atlas provides new tool for understanding estrogen-fueled breast cancer

...egions of genes. "More than 70 percent of breast cancers are ER-positive, meaning their growth is driven by estrogen," Brown says, "and the estrogen receptor is the most important target for therapy for these tumors. Knowing the complete set of ER binding sites gives us a new resource for understanding the...

New way of tracking muscle damage from radiation

...te damage," Krasin said. Soft tissue sarcomas are cancers that arise in muscles, fat, blood vessels and other soft tissues. Ewing sarcoma is a cancer that arises in the bone or soft tissue, usually in the arms, legs, pelvis or chest wall. St. Jude researchers studied the muscles of 13 patients before, d...

An AIDS-related virus tricks cells to become tumors, new Penn study finds

...strategies for treating Kaposi's sarcoma and other cancers associated with viruses. KSHV is an opportunistic pathogen that rarely affects individuals with normal immune systems. However, HIV/AIDS patients and those who are immune suppressed such as organ transplant patients are at high risk for developing K...

Vaccination with embryonic stem cells prevents lung cancer in mice

... develop embryonic stem cell vaccines that prevent cancers in humans, such as hereditary breast and colon can...e of preventing the appearance of various types of cancers in humans, especially those with hereditary, chronological or environmental predispositions to neopl...

Natural anti-viral enzyme helps keep cancer cells alive, researchers find

...of enzymes, which are mutated in 30 percent of all cancers and in 90 percent of pancreatic cancers. The UT Southwestern scientists knew that RalB interacts with a protein complex called the exocyst, which helps small secretory packets in cells fuse to the cell membrane. The team isolated this complex, then...

Clue found to Epstein-Barr virus' ability to form and sustain tumors

...inked to infectious mononucleosis, EBV also causes cancers that kill 100,000 people around the world each year. The virus, which infects the immune system's B cells and causes them to grow, is directly responsible for Burkitt's lymphoma, an often-fatal malignancy affecting thousands of African children annua...

Natural protein stops deadly human brain cancer in mice

...ly proven that they can inhibit lethal human brain cancers in mice using a protein that selectively induces p...th cells that were not pretreated, large, invasive cancers grew. In the mice with BMP4-treated cells, no cancers grew at all. Three to four months after inject...

Studies find general mechanism of cellular aging

...essor gene, and mice lacking p16INK4a develop more cancers than old, normal mice," he said. "Secondly, in all three studies, p16INK4a loss was associated with an improvement in some but not all of the consequences of aging. There are clearly things in addition to p16INK4a that contribute to aging. We don'...

Firefighters face increased risk for certain cancers

...sks of their profession. Risk for 20 different cancers was classified into three categories--probable, possible or not likely--patterned after the IARC's risk-assessment model. UC epidemiologists found that half the studied cancers--including testicular, prostate, skin, brain, rectum, stomach and col...

'Erectile dysfunction' drugs heighten natural anti-cancer activity

...The new Hopkins study homes in on a tactic used by cancers to avoid detection by the immune system by turning elements of that system to its own advantage, says Ivan Borrello, M.D., assistant professor at the Johns Hopkins Kimmel Cancer Center. Borrello and his colleagues found that tumors exploit nitric...

New sunscreen ingredient to heal sunburn and help prevent skin cancer

... lotions. Skin cancer is one of the most common cancers in the UK and the number of people who get it is increasing. There are over 70,000 new cases of skin cancer diagnosed each year in the UK and many cases are not reported so the real number of cases is probably much higher. Over 2,000 people die f...

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