cancers 2 2

Tag: "cancers" at biology news

Researchers identify ovarian cancer biomarkers

... difference between a 95 percent survival rate for cancers found at the earliest stage and 20 percent survival among patients diagnosed with advanced disease. "All the things we could hope for are present with this approach: It has potential for diagnosis, imaging, treatment and prognosis. It needs more w...

UCSD researchers discover variants of natural tumor suppressor

...d that Akt is hyperactivated, or elevated, in most cancers and PHLPP provides a mechanism to reverse this activation. ...

Study calculates patient time costs associated with cancer care

...ional Cancer Institute . The time costs for the 11 cancers studied and for different phases of cancer care va... was highest for patients with gastric and ovarian cancers (21.1 and 20.8 days) and shortest for patients with melanoma (2.2 days), prostate cancer (3.8 days) ...

Breakthrough vaccine to treat chemo-resistant ovarian cancer

...nal cavity. Ovarian cancer, one of the hardest cancers to detect in the early stages, is a very complex disease that is often resistant to chemotherapy. Cancer Treatment Centers of America will offer this new treatment to patients whose cancer has recurred after chemotherapy. "To win the fight agains...

A genetic 'gang of 4' drives spread of breast cancer

...s play a corresponding role in metastasis of other cancers -- such as sarcoma, melanoma and colon cancer -- to the lung, said Massagué....

Genetic pathways to curable and incurable forms of pancreatic cancer identified

...of mutations that determines the behavior of these cancers but also the sequence in which the mutations arise...istant to these effects of TGFb and these types of cancers are also less likely to invade surrounding tissues and to metastasize, or spread, to other organs. T...

New protein inhibitor impedes growth of cancerous cells

...es of patients with locally advanced or metastatic cancers in order to address the therapeutic potential of the compound. In the companion paper, Lenart et al. use BI 2536 as a tool to probe the functions of Plk1 in normal cells. The availability of a specific Plk1 inhibitor is particularly useful in this...

Elucidation of the genome for diabetics with DNA chips

... mysteries shrouding childhood obesity and certain cancers linked to obesity . The work of this French-British-Canadian team was financed principally by the Canadian government and by the province of Quebec. The DNA chips were produced at the genomics centre in Montreal. ...

What's in the water? Estrogenic activity documented in fish caught in Pittsburgh's rivers

... for endocrine-mediated health endpoints like some cancers and developmental problems." ...

Cancer vaccines -- Taking a jab at cancer by stimulating the immune system

...ase, other researchers are developing vaccines for cancers that are not virally based, in an effort to coax the immune system into attacking cancerous cells. Today at the 2007 Annual Meeting of the American Association for Cancer Research, presentations on ongoing HPV trials and other new approaches to stim...

New study may show how to forestall a fatal, virus-caused immune-system meltdown

... factor receptor molecule normally associated with cancers was activated late in infection with the lethal strain of the virus. “We can go in and design an experiment where we can start testing drugs that already have FDA approval,?Bowick said. “If we can go straight from discovery to drug candidates, that’s...

Finnish scientists discovered a new approach to treat virus-induced lymphomas

...n suggested to be a potential treatment option for cancers with wt p53. PEL is a non-Hodgkin type lymphoma latently infected with KSHV, and it manifests as an effusion malignancy in Kaposi’s sarcoma patients. There are no current therapies effective against the aggressive KSHV-induced PEL. KSHV displays t...

Genes and biomarkers that allow doctors to choose the right therapy for the right patient

... to create more effective therapies for individual cancers ?personalized medicine. At the 2007 Annual Meeting... in the subtypes of breast cancer along with other cancers and their subtypes. When therapies are ineffective, they may produce harmful side effects and decre...

Selective marker found to indicate aggressive form of breast cancer

... subtype represents 17 to 37 percent of all breast cancers and is more common in premenopausal African Americ... Consistent with other studies showing that breast cancers associated with inherited mutations in BRCA1 display the basal phenotype, DiRenzo and colleagues fou...

HIV protein enlisted to help kill cancer cells

...rovide new options for patients with the deadliest cancers ?such as pancreatic cancer ?which have very low rates of survival. He says he believes that clinical trials of these compounds could be just a few years away. Hawkins began researching TAT-Bim after discussions with co-author Richard S. Hotchkiss, ...

Gene expression test reveals ER and HER-2 status of breast tumors

...to guide treatment. About 70 percent of breast cancers are estrogen-receptor positive and another 15 to 25 percent are human epidermal growth factor receptor-2 (HER-2) positive. Each receptor status requires different types of treatment. The gene expression tests were 90 percent accurate for both rece...

Molecular signature may identify cisplatin-sensitive breast tumors

...have identified a subgroup of hard-to-treat breast cancers that may be sensitive to the drug cisplatin, rarel... of breast cancer." About two thirds of breast cancers contain receptor molecules for the hormones estrogen or progesterone, and in recent years antiestrog...

Napoleon's mysterious death unmasked, UT Southwestern researcher says

...ing inside the heart, and no skin, lung or bladder cancers were present. Gastric cancer was more likely at fault, Dr. Genta said. Other scholars have recently found that the plump emperor lost at least 20 pounds in the last six months of his life, a sign of gastric cancer. The autopsy descriptions show th...

New test for most virulent HPV strains under study

...human papillomavirus responsible for most cervical cancers is under study. The molecular assay uses a cervi...DA-approved drugs to cure cervical pre-cancers and cancers caused by HPV, although centers such as MCG are evaluating potential therapies. Resulting cervical c...

Speeding 'fingertip' discovery -- 20 years of protein info in 1 place

...p us understand some of these diseases - including cancers - sooner. “What we have here is about 20 years?worth of lots of work in one searchable list,?says Pandey. A report on all of the newly identified protein alterations is published in the Feb. 13 issue of the Proceedings of the National Academy of ...

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