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Tag: "cancers" at biology news

Enzyme delivered in smaller package protects cells from radiation damage

...ften is given to patients with blood and lymphatic cancers to wipe out their bone marrow cells prior to subse...tients receiving total body radiation for systemic cancers better long-term outcomes. This also has implications for the prophylactic protection of those who m...

Blood test may help signal tumor's remission, return in throat cancer patients

...ongly associated with throat cancer, especially in cancers arising from the tonsils and base of the tongue. In the largest long-term study of its kind, NIH and University of Michigan researchers tested the blood of 30 patients who had undergone chemotherapy and radiation treatment for advanced throat canc...

Loss of stem cells correlates with premature aging in animal study

...gy fields since premature aging syndromes and many cancers involve the loss of DNA repair genes.” When the researchers deleted ATR in the tissues of adult mice, they noticed that the mice showed signs of premature aging, such as hair graying, hair loss, and osteoporosis, within three to four months. T...

Study shows big power of small RNAs, not just proteins, in halting cancer

...amage to this pathway is something that almost all cancers have in common,” said CSHL Cancer Center Deputy Director and HHMI Scott Lowe. “Collaboration among different CSHL research laboratories has not only found that p53 can arrest the growth and even eradicate cancers, but we’ve revealed something very...

Studies to find better ways to preserve human eggs, ovarian tissue under way

...or leukemia and cervical, ovarian, breast or other cancers often leaves women infertile because systemic chemotherapy and more focused radiation therapy, designed to kill rapidly spreading cancer cells, also can destroy dynamic reproductive tissue. “I don’t think when you are faced with the reality that ...

Sun exposure early in life linked to specific skin cancer gene mutation

Skin cancers often contain different gene mutations, but just how these mutations contribute to the cause of melanomas has been a mystery. A new clue comes from scientists at the University of North Carolina at Chapel Hill Schools of Medicine and Public Health. ...

Rising skin cancer rates are more likely to affect wealthy people, says 12-year review

...igures also showed that the three most common skin cancers - basal cell carcinoma, squamous cell carcinoma an...t melanoma - accounted for 27 per cent of all male cancers and 26 per cent of all female cancers. “These findings show that many patients will have more th...

U-M researchers discover gene switched off in cancer can be turned on

...s in large amounts, causing cancer to develop. But cancers also arise because genes that control growth are turned off. While researchers can use these turned-off genes to identify or monitor cancer, currently no treatments actually target these genes. U-M researchers found that a gene called Brahma, or B...

Researchers shed light on mechanism of action used by anti-cancer drug

...olecularly targeted agents for patients with blood cancers and solid tumors. In the new study, led by Steven Grant, M.D., Massey’s associate director for translational research and co-leader of the cancer center’s cancer cell biology program, VCU researchers identified a mechanism by which sorafenib inhibi...

Could fungal collection hold the key to new life-saving drugs?

...ne step closer to finding new drugs to fight MRSA, cancers and other diseases, after CABI, a leading bioservices organisation announced that its fungal collection will be screened by the University of Strathclyde. CABI houses one of the world’s largest genetic resource collections of fungi, numbered at over...

Cancer stem cells similar to normal stem cells can thwart anti-cancer agents

... According to Dr. Donnenberg, the very fact that cancers can and do relapse after apparently successful therapy indicates the survival of a drug-resistant, tumor-initiating population of cells in many types of refractory cancers. “Because of the similarities between the way that normal stem cells and cance...

Mutating the entire genome

...so can create new genes from two other genes. Many cancers – certain sarcomas, leukemias and lymphomas – start with translocation. Existing methods result in the desired translocation of two chromosomes in one of every 1 million to 10 million cells cultured, Capecchi says, while the new method produces t...

Master regulatory gene of epithelial stem cells identified

...em cells. The findings also have implications for cancers of the skin, breast and prostate, which are among the most common human malignancies. The role of p63 in epithelial stem cells has been controversial. Some studies found that p63 maintains a steady pool of the regenerative cells, while other studies...

Cancer patients monitor fatigue in real time

...ving problems breathing -- another symptom of some cancers -- may also experience fatigue." According to Hacker, this is the first study of real-time collection of fatigue data in acutely ill cancer patients. Ecological momentary assessment holds substantial promise for investigating fatigue and other can...

Risk of lymphoma increases with hepatitis C virus infection

...lationship between hepatitis C virus infection and cancers of the lymphatic system," said NCI Director John E. Niederhuber, M.D. "Since so much is still unknown about the causes of lymphoma, establishing which factors contribute to the disease is the first step in finding ways to reduce its incidence and le...

Dealing deadly cancers a knockout punch

...therapy can stop or reverse the growth of advanced cancers without adding harmful side effects," said Dr. Mettinger. ...

Heavy multivitamin use may be linked to advanced prostate cancer

...th prostate cancer, including 8,765 with localized cancers and 1,476 with advanced cancers. The researchers found no association between multivitamin use and the risk of localized prostate cancer. But they did find an increased risk of advanced and fatal prostate cancer among men who used multivitamins m...

Effect on breast tumors of DNA alternations in 3 genes described

...methylation is potentially reversible, identifying cancers with different hypermethylation may have important consequences for breast-cancer treatment."...

Researchers wake up viruses inside tumors to image and then destroy cancers

... strategy could offer a novel way of treating many cancers associated with Epstein-Barr, including at least f... transfect cells." A variety of blood and solid cancers are more likely to occur in people who have been infected with the Epstein-Barr virus (EBV), but not...

Gut research yields new anti-cancer approach

...ew way to fight colorectal cancer, and potentially cancers of the esophagus, liver and skin. Early work shows...kin, we see potential for a new way to treat those cancers as well." In the study that led to the discovery of the anti-cancer effect, researchers were look...

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