TEL2 gene cooperates with MYC gene to provoke B-cell lymphomas
...to commit suicide--ridding the body of potentially cancerous cells. "The study's findings strongly suggest tha... However, such rogue cells can still become fully cancerous if they succeed in eliminating p53 activity, in effect silencing the command to commit suicide. This...Newly Discovered Compound Blocks Known Cancer-Causing Protein
... independently in soft agar, a typical test of the cancerous potential of cells. "The next step is to test cysmethynil in animal models," said Casey. "We don't know how the compound will be metabolized in living animals, but we are encouraged by our initial results." Other Duke scientists contributing to the...Circles Of DNA Might Help Predict Success Of Stem Cell Transplantation
...liminate the patients' own stem cells that produce cancerous white cells or faulty red cells and replace them with healthy stem cells from donors. If the transplants succeed, the donated stem cells repopulate the blood with healthy red and white cells. The St. Jude team showed that the more copies of tiny rin...Potential Cure for Lymphoma in HIV patients
... combination withradiation therapy, to destroy the cancerous cells. Most (17 patientsversus three) received the...es or thepatient had bulky disease (indicated by a cancerous mass greater than 5?10 cm).Reversible abnormalities in liver function, a side effect of theintensive......lesof melanocytes, which are the cells that become cancerous in melanoma,we would love to identify a signal that would make a melanoma cell stopgrowing.?Fisher and the report’s lead author, Emi K. Nishimura, MD, PhD, also ofthe melanoma program, are in the Department of Pediatric Oncology atChildren’s Hospital...Fundamental Finding Yields Insight into Stem Cells, Cancer; Opens Door to Drug Discovery
...lesof melanocytes, which are the cells that become cancerous in melanoma,we would love to identify a signal that would make a melanoma cell stopgrowing.?Fisher and the report’s lead author, Emi K. Nishimura, MD, PhD, also ofthe melanoma program, are in the Department of Pediatric Oncology atChildren’s Hospital...Scientists discover the cellular roots of graying hair
...lesof melanocytes, which are the cells that become cancerous in melanoma,we would love to identify a signal that would make a melanoma cell stopgrowing.?Fisher and the report’s lead author, Emi K. Nishimura, MD, PhD, also ofthe melanoma program, are in the Department of Pediatric Oncology atChildren’s Hospital...U-M scientist to talk about tissue engineering at AAAS
...d. To heal a large wound, like that created when a cancerous tumor is removed from the jaw, that often means taking a bone graft from someplace like the hip. That approach has problems both for the wound at the donor site and for the site where it is implanted. In addition to discussing the sometimes-messy re...Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible
...issue samples were derived from multiple normaland cancerous tissues. The labs followed a common protocol for allsteps of sample preparation and microarray analysis and the resultinggene expression profiles were analyzed and compared.Sample correlation within each lab was extremely high; microarray datafrom th...Source of molecular triggers in cutaneous T cell lymphoma identified
...esearch group reported that, like all T cells, the cancerous CTCL cells require antigenic stimuli delivered by specialized dendritic cells of the epidermis, referred to as Langerhans cells (LC), in order to replicate. To determine the nature of the activating antigen, Carole Berger, a research scientist in de...