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Tag: "cancerous" at biology news

Killing brain tumors from within: A 'Trojan horse' approach

...geting malignant brain tumors through inducing the cancerous cells to "commit suicide" has been developed by a ...so be applied to other types of receptors found on cancerous cells, he added. Last year, Prof. Levitzki was named as a winner of the prestigious Wolf Prize i...

MIT nanoparticles may help detect, treat tumors

...y MIT engineers may one day help physicians detect cancerous tumors during early stages of growth. The technique allows nanoparticles to group together inside cancerous tumors, creating masses with enough of a magnetic signal to be detectable by a magnetic resonance im...

Major cancer study aims to identify protein markers for early-stage disease

... of intense interest to cancer researchers because cancerous tumors "leak" proteins and other molecules into blood, urine and other accessible bodily fluids early on in their development. This knowledge is already being applied in the clinic: Elevated levels of prostate specific antigen (PSA) hint at the pre...

'LEGO-Like' building blocks to halt cell growth wins Hebrew University prize

...f the IGF-1 protein in the cells, thus halting the cancerous growth. Through this process of "combinational chemistry," involving peptides and scaffold design, Qvit says that many different types of molecules can be built that will reach specifically targeted cells, offering hope for treatment of not only ca...

Research links protein to breast-cancer migration

...ng the protein's actions has the potential to stop cancerous cells migrating. "What we have identified is a ne...target the LPP protein and stop it from working in cancerous cells, we have a possible new route to therapy." The research, published in the scientific journal ...

Coming soon: 3-D imaging that flies 'through' and 'around' cancer

...a with accurate anatomical information of possible cancerous tumors--from inside the body--provides a visual na... peel away the organs, highlight tumors and detect cancerous 'hot spots'--providing an omnipotent perspective of the body," he indicated. Stanford's 3-D fusion i...

Tumor wizardry wards off attacks from the immune system

Like the fictional wizard Harry Potter, some cancerous tumors seem capable of wrapping themselves in an i...immune reactions. The scientists discovered that cancerous cells take advantage of T-reg cells' suppressor ability, enlisting them to keep the immune system at...

Combined treatment extends life expectancy for lung cancer patients

...is vital to help the radiation damage DNA and kill cancerous cells. While radiation is most effective in destro...lation, on the other hand, heats the tumor to kill cancerous cells ?reaching the center of the tumor, but not necessarily killing all the cells at the edges. Thi...

Failure of 'scout cells' may lead to cancer in transplant patients

...ells are re-stimulated properly, they can kill the cancerous cells before PTLD develops, VanBuskirk says. But if that re-stimulation is weak or is blocked, not all of the cells are destroyed and cancer can develop. So it is critical that these two cell types work together effectively. The present study sugg...

New strategy rapidly identifies cancer targets

...viously unknown genetic mutations that can trigger cancerous growth. By analyzing the proteins ?instead of the genes ?inside acute myeloid leukemia (AML) cells, the researchers have dramatically reduced the time it takes to zero in on molecular abnormalities that might be vulnerable to specific drug treatments...

Heal thyself: Systems biology model reveals how cells avoid becoming cancerous

...onses that cells use to avoid becoming diseased or cancerous after being exposed to a powerful chemical mutagen. The group led by UCSD bioengineering professor Trey Ideker describe in the May 19 issue of Science an elaborate system of gene control that is triggered by chemical damage to DNA. "This research s...

U of M researchers discover genetic key to treating deadly fungal infections

...al treatment." Berman also explained that some cancerous tumors contain isochromosomes, which means that the finding may yield clues about how some tumors become resistant to chemotherapy and how researchers can develop companion drugs that inhibit the development of that resistance. About 25,000 Ameri...

Cigarette smoke blocks cell repair mechanism, University of Florida study shows

Cigarette smoke can turn normal breast cells cancerous by blocking their ability to repair themselves, eventually triggering tumor development, University of Florida scientists report. While some cells nonetheless rally and are able to fix their damaged DNA, many others become unable to access their ow...

Cycles of cell death, proliferation key to liver cancer

..., it stimulates proliferation of pre-malignant and cancerous tumor cells," said Karin. Blocking JNK prevents l...nt. When JNK1 was removed, the number and size of cancerous liver tumors decreased, and the tumors grew more slowly. Increased JNK1 activation was found in dise...

Researchers map out networks that determine cell fate

...in which a persistent mixed lineage seems to drive cancerous proliferation. Although the researchers worked only with blood-forming stem cells, they suspect that the same basic regulatory principles govern cell type determination in other tissues such as skin, brain and intestine. "We see elements of this f...

Speeding discovery of the 'human cancer genome'

...he ride with those that actually contribute to the cancerous cells' ability for unchecked proliferation or spread. Simply sorting through those differences one by one takes time and money, said Lynda Chin of the Dana-Farber Cancer Institute and Harvard Medical School. "There has to be a way to prioritiz...

New device could cut chemotherapy deaths

...hemotherapy drug which are then implanted into the cancerous area in the patient's body. These fibres are bio-degradable and compatible with body tissue, which means they would not be rejected by the patient's body. They gradually turn from solid to liquid, releasing a regular flow of the chemotherapy chemica...

Mayo Clinic researchers discover cancer cells may move via wave stimulation

... which allows them to "instruct" a cell to acquire cancerous traits such as excessive growth and invasive movement that constitute metastasis. These waves are important for helping to keep these cancer-growth commands at bay. Studying human pancreatic tumor cells, the Mayo researchers found that the waves sto...

AIDS-related cognitive impairment exists in two separate forms

...fference between miRNA expression in normal versus cancerous colon tissues should provide insight into mechanisms of colon cancer development and identify novel drugs to treat the disease" he said. Expression Profiles of 16 Genes Predict Prostate Carcinoma Relapse and Disease Free Survival in Formalin-Fixed,...

Markers of gene, protein, or micro-RNA activity predict outcome in prostate and colorectal cancers

...fference between miRNA expression in normal versus cancerous colon tissues should provide insight into mechanisms of colon cancer development and identify novel drugs to treat the disease" he said. Expression Profiles of 16 Genes Predict Prostate Carcinoma Relapse and Disease Free Survival in Formalin-Fixed,...

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