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Tag: "cancer" at biology news

Survey reveals women and doctors aren't talking about HPV

...aid their doctor has talked to them about cervical cancer and its cause - the human papillomavirus (HPV) - a...ng about the relationship between HPV and cervical cancer despite the fact that advanced screening is available, which can detect the virus early and help pre...

New understanding of cell movement may yield ways to brake cancer's spread

...cells zero in to destroy pathogenic organisms, and cancer cells metastasize, spreading deadly disease throug...ar migration can help develop treatments that halt cancer metastasis and immune disorders like arthritis and asthma. "Previous studies by us and others have ...

Gene silencing technique offers new strategy for treating, curing disease

...nhibited the expression of nine different genes in cancer cell cultures. Dr. Corey said it's not clear whether the RNA is actually binding to the DNA itself, as the PNAs do, but it's clear the effects are occurring at the DNA level. ...

U of T researchers map role of Epstein-Barr virus in cancer

...like the human papillomavirus that causes cervical cancer for example, have been shown to work through this p53 protein, but up until now, no one's ever found any regulation of p53 that's associated with the Epstein-Barr virus. That was surprising because all other viruses that stimulate cell proliferation ...

UCLA cancer researchers shake loose hidden biomarker

...a hidden target into an exposed one. "In prostate cancer cells, PSMA is expressed in the apical region of t... Rajasekaran and his team employed a commonly used cancer chemotherapy agent, which destroys the microtubules. "These patients are getting chemotherapy anywa...

Natural tumor suppressor in body discovered by UCSD medical researchers

...sor that could potentially be turned on in certain cancer cells to prevent the formation of tumors has been ...ontrols the balance between cell growth leading to cancer and cell death that prevents tumor formation. "A drug that turns on PHLPP, so that it suppresses ce...

Massey Cancer Center researcher helps to identify a piece of the cancer puzzle

...derstanding of the cell signaling that occurs when cancer cells try to co-opt nearby healthy cells into help...r explore how to turn off the signals that promote cancer growth," said William A. Barton, Ph.D., a VCU alumnus who recently returned to Richmond to continue ...

Cancer drug slows poxvirus in mice

Mice given a relatively new cancer drug can survive an otherwise lethal dose of vacci...ced "able") of tyrosine kinases, are well known to cancer investigators because mutation of one family member, Abl, causes a rare form of cancer known as chro...

Cancer related gene p53 not regulated as indicated by previous tissue culture research

...ors." Many chemotherapeutical drugs used to treat cancer exert their biological effects on tumor cells through activation of the p53 pathway. Having an accurate view of how p53 is regulated will allow the development of specific drugs that unleash the killing power of p53 by interfering with its negative r...

High-powered gene profiles provide clues to genes involved in common form of lung cancer

...tentially involved in the most common type of lung cancer –?and one of the deadliest of all malignancies –?a...over again –?which suggests that a large number of cancer genes remain to be discovered. The purpose of this study was to locate the likeliest candidates." T...

Moffitt-USF head toward first human trials of anti-cancer drug that targets protein AKT

.... The compound, tricirbine, was tested at various cancer centers from 1982 to 1996 and found to inhibit som...nstance, because "40 percent of women with ovarian cancer have tumors with high levels of active Akt," according to Sebti. "To our knowledge, this is the fir...

MIT engineers an anti-cancer smart bomb

Imagine a cancer drug that can burrow into a tumor, seal the exits ... commentary. "We brought together three elements: cancer biology, pharmacology and engineering," said Ram Sasisekharan, a professor in MIT's Biological Engin...

The making and breaking of microtubules

...targeted to put a monkey wrench into the growth of cancer cells. "Nucleotide-dependent bending flexibility of tubulin regulates microtubule assembly," by Hong-Wei Wang and Eva Nogales, appears in the 16 June 2005 issue of Nature. ...

Open Access journals get impressive impact factors

...2.98 and remains the second highest ranking breast cancer journal. Arthritis Research & Therapy maintains its rank of second in the rheumatology field with an impact factor of 4.55. A number of other journal published by BioMed Central also saw their impact factors and rankings improve. BMC Infectious ...

'Bionic' arm gives amputee sense of touch

...2.98 and remains the second highest ranking breast cancer journal. Arthritis Research & Therapy maintains its rank of second in the rheumatology field with an impact factor of 4.55. A number of other journal published by BioMed Central also saw their impact factors and rankings improve. BMC Infectious ...

Bacterial genome sheds light on synthesizing cancer-fighting compounds

...atellamides, compounds that may one day be used in cancer treatment. Despite decades of attempts, scientists could not successfully cultivate Prochloron in the laboratory once the bacterium was isolated from the sea squirt. Because samples of Prochloron were easily contaminated with remnants of life inside...

Scientists inhibit cancer gene

...n the pancreas, colon and lung, as well as thyroid cancer and leukemia. Attempts to inhibit activated Ras have had limited success until now, but the Huntsman Cancer Institute researchers explain that they have discovered an enzyme that, when inhibited, appears to reduce the incidence of Ras-induced tumors...

Researchers develop promising new gene network analysis method

...eractions and pinpoint genes that may be potential cancer treatment targets, according to new Brown Universi...ns, a task critical for understanding and treating cancer and other diseases. Results appeared this week in the online edition of the Proceedings of the Natio...

One hit of crystal meth causes birth defects

...tive oxygen molecules that have been implicated in cancer and neurodegenerative diseases, says Wells. This vulnerability lasts from the embryonic stage through the later fetal period, times when organ structures and mental functions develop. "People usually think the last trimester of pregnancy is when dev...

Arthritis: What Wnt wrong?

... proto-oncogene because its disruption can lead to cancer in various organs such as colon, lung, and breast. However, mounting evidence also points to its involvement in arthritic joint disease. Comprehensive analysis of the entire Wnt gene family in the progression of arthritis has been lacking until now. ...

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