Compounds in plastic packaging act as environmental estrogens altering breast genes
...gens in the Human Breast." "Development of breast cancer entails multiple events, in which estrogen appears...olved in breast development and possibly in breast cancer may include foreign estrogens, or xenoestrogens, that are used in manufacturing a number of products...NSAID drug protects against intestinal tumors in mice, despite poor diet and gene losses
...n-style diet - even when several genetic brakes to cancer formation were missing in the animals, say researc...nutritional and medicinal agents in development of cancer in the intestines. The drug they tested, sulindac, was a highly effective chemoprevention agent, th...Measuring Enzymes At End Of Cancer Pathway Predicts Outcome Of Tarceva, Taxol
...of numerous cellular pathways that are involved in cancer development and progression, the researchers say. ...redictive test currently available is whether lung cancer cells have a mutation in their epidermal growth factor receptor (EGFR), but that does not predict re...Confocal imaging promises early detection of skin cancer
Skin cancer is on the increase. Recent statistics for Germany ...e visits with just one visit and by detecting skin cancer as early as possible, to offer patients the most complete treatment.?/p> Doctors can choose from...UCLA scientists store materials in cells natural vaults
...uding: * Therapeutic delivery, such as homing cancer drugs directly to a tumor cell without harming healthy tissue * Enzyme delivery to replace missing or defective enzymes, such as those that cause Tay Sachs disease * DNA delivery to correct genetic mutations * Timed release of drugs, enzy......reviously untreated recurrent or metastatic breast cancer ?cancer that has spread from the breast to other p...chemotherapy had a longer time period before their cancer progressed than patients who received the same chemotherapy without bevacizumab. The clinical trial...Study reveals candidate targets for anti-retroviral therapeutics
... used as a model to help scientists understand how cancer cells replicate out of control. The Sandmeyer laboratory, which has expertise in genetics and biochemistry, screened a collection of over 4457 mutant yeast strains representing most of the known genes in yeast. They then solicited the help of comput...Product improves peptide identification for proteomics research
...leading to a better understanding of diseases like cancer and speeding drug development efforts. The Agilent 1100 Series LC/MSD Trap XCT Ultra offers significantly improved scan cycle times, enabling collection of mass spectra at rates up to three times faster than its predecessors. "The combination of the...MUHC researchers make cancer target breakthrough
...t a reduction in the growth of both colon and lung cancer tumors with inhibition of the gene. The new targe...onine--a critical nutrient necessary for growth of cancer cells," explains Dr. Rima Rozen, principal investigator of the new study, and Deputy Scientific Dire...Findings have implications for tracking disease, drugs at the molecular level
...ton imaging, in which specific tissues or cells -- cancer cells, for example -- are fluorescently-labeled using special stains that enable them to be studied. "One of the most exciting aspects of this technique is that it paves the way for being able to observe behavior in living tissues at the single mole...Disease progression model of pancreatic cancer developed by Penn researchers
...icine have developed an animal model of pancreatic cancer that closely mimics disease progression in humans....ments for this deadly disease. Advanced pancreatic cancer is among the most lethal of cancers, with a one-year survival rate after chemotherapy of only 17 to ......tudy designed to better understand mesothelioma, a cancer found in the lining of the chest, the abdominal ca...cted to peak about 2010. Diagnosis of this type of cancer is difficult, and patients are often not identified until the condition is quite advanced. Agilent'...New polysaccharide may help combat multidrug resistance in cancer
...chers were able to sensitize drug resistant breast cancer cells to chemotherapeutic drug treatment. The res... cancers, making it one of the leading problems in cancer therapy. It is often caused by an increase in the cell's production of proteins that transport drugs...The circadian clock: Understanding nature's timepiece
...g shifts are at greater risk for developing breast cancer than their counterparts on regular day shifts. "If your sleep schedule is constantly changing, you can't help but be less alert," Antle says. "When you look at disasters such as plane crashes, or Three Mile Island or Chernobyl, there is often a slee...Researchers develop assay that could be applied to drug screening
...lation of CME has been implicated in some types of cancer and neuro-degenerative disease and the protein machinery of CME has been co-opted by several viruses, including rabies, as a means of entry into healthy cells. The researchers led by David Zenisek, assistant professor in the Department of Cellular a...Master gene controls healing of skin in fruit flies and mammals
... of the UCSD paper. "It also opens new avenues for cancer research, since many cancer cells activate genes normally involved in wound healing in order to kick start processes such as cel......echanism of topoisomerase IB is also important for cancer research. Drugs which inhibit the functioning of topoisomerase IB are already in clinical use, but can possibly be improved using the knowledge from this study. ...Unchecked DNA replication drives earliest steps toward cancer
... not widely appreciated as a disease of the genes, cancer is always rooted in genetic errors or problems in ... identified some of the first genetic triggers for cancer as mutations in specific oncogenes or tumor suppressor genes. Full-blown tumors and metastatic cance...Science study holds implications for gene therapy and stem cell biology
...clinical trials to treat severe inborn diseases or cancer in humans. Retrovirus-based gene transfer vectors are partially defective retroviruses that integrate into the genome of a cell, thus potentially increasing the activity of neighboring genes. A previous study by Dr. Baum and team revealed that the ......our understanding of the second most fatal form of cancer in the industrialized world. Professor Jeremy R. J...and Japan have shown that in some cases colorectal cancer can be inherited. The new syndrome is characterized by distinctive clinical, pathological and molecu...