Same-Sex Mating Discovered in a Toxic Fungus
...d patients such as organ transplant recipients and cancer patients -- whose immune systems are crippled by immunosuppressive drugs or chemotherapy -- and people with HIV/AIDS. The fungus' global importance as a health threat has therefore risen in parallel with the increased use of such therapies and with t...Technique may allow cancer patients to freeze eggs, preserving fertility before starting treatment
A new technique might allow women diagnosed with cancer the opportunity to have children when chemotherapy...ound. By having her eggs frozen before she begins cancer treatments, a woman can preserve the hope of one day having a baby. Freezing eggs is one thing; tha...Test for early detection of prostate cancer shows promise
...und that the marker, called EPCA or early prostate cancer antigen, can successfully detect prostate cancer in its earliest stages. At the same time, the marker successfully avoids the problem of false positi...PET/CT can identify new cancer lesions at early stage, allowing for prompt treatment
...diological Science. PET/CT scans from nearly 2,000 cancer patients over a two-year period were evaluated ret...ately diagnose breast cancer, melanoma and ovarian cancer and that it was superior to CT in staging lung cancer. Wahl explained that in patients with known c...Used in a new way, RNA interference permanently silences key breast cancer gene
...rence (RNAi) so that it permanently hampers breast cancer development. The technique permanently silences ac...in RNA, shRNA) for mouse STAT3 into a mouse breast cancer cell line. They chose STAT3 because when activated, it is involved in the formation of multiple type...Bioelectronic ‘signatures?hold key to DNA mutations
...ind individual genetic variation and diseases like cancer are fine differences ?single nucleotide polymorphisms, or “SNPs??buried within the 3 billion chemical bases of DNA comprising the human genome. Not every SNP found will necessarily cause a mutation or determine our eye or hair color ?but, on average,...Nanoparticle Breast Cancer Drug Approved by FDA
...e approval means that women with metastatic breast cancer no longer need to endure the toxicities associated...ern Memorial Hospital. Gradishar is also a breast cancer researcher at The Robert H. Lurie Comprehensive Cancer Center of Northwestern University. "In our r...New understanding of DNA repair may pave way to cancer treatments
...f radiation, as well as changes that take place in cancer and pathologic situations, can activate both functions of ATF2, which is expected to disturb the otherwise conserved balance between its role in gene regulation and the DNA damage response. We need to find out which of the two functions is more domin...Biomarkers isolated from saliva successfully predict oral and breast cancer
Screening for breast cancer and the early detection of other tumors one day ma...primary oral squamous cell carcinoma and 40 breast cancer patients, and matched each with saliva and blood from otherwise normal subjects. New techniques were...Cooperation is key—a new way of looking at MicroRNA and how it controls gene expression
... mechanisms that underlie many diseases, including cancer and septic shock. The discovery concerns tiny fragments of RNA known as microRNA and their relationship to the genetic transcripts known as messenger RNA (mRNA). All genes expressed in the human body must be transcribed as mRNA before they can be t...Insight into DNA's 'weakest links' may yield clues to cancer biology
... insight into the chromosomal instability found in cancer cells, said the researchers. "If you look at soli... tumors in humans, you see that the chromosomes of cancer cells exhibit incredible instability," said Thomas Petes, Ph.D., chair of genetics and microbiology ...Turning viruses into allies against cancer
... a potent immune stimulant to thwart the spread of cancer cells, is being tested in patients with a variety ...b is to induce an immune response to any surviving cancer cells released during the initial viral attack, essentially preventing the spread of these cells to ...Novel gene-silencing nanoparticles shown to inhibit Ewing's sarcoma
...s of Ewing's sarcoma, a rare and often deadly bone cancer that generally strikes young adults. Despite aggressive therapy, about 40 percent of patients with Ewing's family tumors and 95 percent with metastases die as a result of their disease. Scientists now recognize that Ewing's sarcoma results when two ...Protein helps regulate the genes of embryonic stem cells
...ing how epigenetics influences such occurrences as cancer and birth defects, he added. The discovery that e... may give us new gene targets to study relative to cancer and other disease states that may have these marks and have not been examined but should be," Magnus...Chromosome Deletion Predicts Aggressive Neuroblastoma
... the result is an aggressive form of the childhood cancer neuroblastoma. A new study suggests that detecting...zation that supports clinical trials for pediatric cancer patients. Neuroblastoma, which accounts for 10 percent of all pediatric cancers, often occurs as a ...Researchers find promising cancer-fighting power of synthetic cell-signaling molecule
... National Cancer Institute. "Many agents suppress cancer cells in a Petri dish and then not in the whole an...phingolipid analogs might be even better at making cancer cells behave more normally. Merrill and his collaborators have been studying sphingolipids for more...Biochemists report discovery of structure of major piece of telomerase; implications for cancer
...ry conducts basic research, and is not involved in cancer treatment. Every time a cell divides, telomeres, ...n our bodies, it is active in the vast majority of cancer cells, Feigon said. Because cancer cells divide rapidly, their telomeres should get shorter more qu...NYU and MSKCC research provides model for understanding chemically induced cancer initiation
... chemical DNA damage and cigarette-associated lung cancer has been called the "smoking gun." In the study, ... understand how chemicals can induce mutations and cancer at the molecular level," added NYU's Broyde. "Such information is needed for devising novel preventi...Study reveals dramatic difference between breast cancers in US and Africa
...apies. "We have known for a long time that breast cancer is not one disease and that it may be somehow diff...ethink how soon and how often we screen for breast cancer in women at risk for the most aggressive type of breast cancer, as well as how we prevent it and how...