Imaging Lymph Nodes with Nanoparticles
... novel application involving the buzzword "nano" - cancer detection using nanoparticles and MRI (magnetic resonance imaging) : Accurate staging of cancers is one of the most important parts of thework up of patients for both prediction of prognosis and determinationof the most appropriate treatment. And an...U-M scientist to talk about tissue engineering at AAAS
... bone of a person undergoing radiation therapy for cancer means managing the constant bacteria bath of a human mouth as well as compensating for the damage of radiation. "It's not just a question of whether we can make new tissue in a perfect condition. Now we're mimicking what can really happen in a perso...Genome-wide mouse study yields link to human leukemia
...pressor gene. Tumor suppressor genes help control cancer by identifying and getting rid of defective cells ...hrough methylation or some other process, it gives cancer a chance to establish a foothold and spread. Caligiuri says much more work needs to be done, but ad...Breakthrough Microarray-based Technology for the Study of Cancer
...slocation of DNA from one chromosome toanother, as cancer develops. Understanding these changes is key tounderstanding cancer progression as well as developing possibletherapies and prognostic and diagnostic tools."Genomic alt...Live Recombinant Adenovirus Vaccine Technique Explored
...loping world. HPV causes 500,000 cases of cervical cancer each year worldwide. Recombinant HPV vaccines currently in clinical trials may not be ideal in poorer countries because they are expensive and require multiple immunizations. The Hopkins researchers developed their vaccine prototype using canine ora...Leukemia Drug Breakthrough Study In New England Journal Of Medicine
...genesis) and stimulates the immune system to fight cancer cells. The study is reported in the Feb.10 issue o...d contributions to clinical trials, prevention and cancer control. Additionally, Moffitt is a member of the National Comprehensive Cancer Network, a prestigio...Mitochondrial DNA mutations play significant role in prostate cancer
...,Irvine, sequenced segments of mtDNA from prostate cancer patients andfound a variety of mutations, includin... They then sequenced the COI gene in 260 prostate cancer tissue samplesor blood cells from patients with confirmed cancer who had undergoneradical prostatect...Gene therapy converts dead bone graft to new, living tissue
...e, is a promising development for the thousands of cancer and trauma patients each year who suffer with frag...t will have a dramatic effect on success rates for cancer patients who would otherwise be facing choices as drastic as amputation," says Arthur A. Gertzman, e...Molecular machine may lead to new drugs to combat human diseases
... paths for treating diseases such as some forms of cancer and opportunistic infections that plague HIV patients. Purdue University researchers froze one of these molecular machines, which are chemical complexes known as a Group I intron, at mid-point in its work cycle. When frozen, crystallized introns rev...Sea skate experiment sheds light on human cell transport
...se channels and the uncontrolled multiplication of cancer cells," Goldstein said. "If so, this research points up an important area for future research." ...Yale Scientists Find MicroRNA Regulates Ras Cancer Gene
... maps to a chromosomal region associated with lung cancer as a regulator of Ras expression. DNA of plants a...it acts like a brake on an accelerated Ras." Lung cancer currently has a poor prognosis with less than 15 percent of patients surviving five years. The lungs...New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
...elp doctors determine early in the course of brain cancer regimen if a patient's tumor will shrink, a new st...g therapy to determine if the tumor shrank. If the cancer did not respond to the treatment, a new approach may be tried. Using diffusion MRI and the function...Enzyme shown to help protect genomic stability
...meres, such events may accelerate aging or trigger cancer in humans." "We have identified a molecular mechanism to explain how this enzyme helps keep telomeric DNA silenced and potentially protects the genome from destabilizing activity," says N.C. Tolga Emre, a graduate student in Berger's laboratory and ...BRCA1 causes ovarian cancer through indirect, biochemical route
Mutated BRCA1 genes cause ovarian cancer indirectly, by interfering with the biochemical si...ween different cell types." The well-known breast cancer gene, BRCA1, not only gives carriers of its mutated form a four in five chance of developing breast ...Scientists decipher genome of fungus that can cause life-threatening infections
...y,including those who have HIV/AIDS or who receive cancer chemotherapy,steroid treatments, or therapy to prevent rejection of transplantedorgans. One study indicated that as many as 13 percent of AIDS patientssuffer a life-threatening cryptococcal infection at some point duringthe course of their HIV diseas...Needling Chromosomes Reveals Cell Division Secret
...This creates chromosome imbalances thatcan lead to cancer or chromosomal abnormalitiesthat cause birthdefects."According to Nicklas, it was known that the two sister chromatidsadhered to one another and released at the appropriate time during celldivision. However, that understanding was based on biochemica...Researchers identify target for cancer drugs
...hat may present drug makers with a significant new cancer target. "We believe that we have identified a component that researchers have been looking for since 1996," says Whitehead Associate Member David Sabatini, who is also an Assistant Professor of Biology at MIT. At the heart of this new research is a...Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease
...th," Bernstein notes. "Some of the genes can cause cancer directly when altered by mutations." "The work we're doing now is very fundamental," he says. "But what we learn about the interactions between chromatin, its tags, and various proteins that interact with them may one day be useful for understanding...First 'atlas' of key brain genes could speed research on cancer, neurological diseases
...’s laboratory is focused on thestubborn problem of cancer pain: He and his students are screening theatlas f...theHarvard Medical School and is among the leading cancer research andcare centers in the United States. It is a founding member of theDana-Farber/Harvard Can...U-M scientists find genes that control growth of common skin cancer
...y in basal cell carcinoma ?the most common form of cancer ?anduncovered a subset of tumor cells that were re...CCs, as well as other cancers. In contrastto other cancer models where inhibition of Hh signaling leads todurable tumor regression, Dlugosz's new work raises ...