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Tag: "cancer" at biology news

First production of human monoclonal antibodies in chicken eggs published in Nature Biotechnology

... ability to be internalized by antigen on prostate cancer cells. At the same time, chicken-produced antibodies lacked the sugar residue, fucose, which greatly increases their cell-killing activity compared to CHO-produced antibodies." To create the antibody-producing chickens, the researchers first inserte...

Major breakthrough in the treatment of cancers and infectious diseases

... cells are responsible for recognizing and killing cancer cells and cells infected by viruses such as the vi...f NK cells that are much more effective at killing cancer cells. Inhibiting the function of EAT-2 with medications could therefore stimulate the killer functi...

Virginia Tech group adds tools to DNA-targeted anti-cancer drugs

...ules they are creating to deliver killing blows to cancer cells. The man-made molecular complexes enter cancer cells and, when signaled, deliver killing medicine or cause the cell to change. The new supermolecul...

Bad aftertaste? New sensory on/off switch may 'cure' bane of artificial sweetener search

...ules they are creating to deliver killing blows to cancer cells. The man-made molecular complexes enter cancer cells and, when signaled, deliver killing medicine or cause the cell to change. The new supermolecul...

Purdue scientists may have found key to halting spinal cord damage

...e. Because acrolein has already been implicated in cancer and neurological diseases, drugs that detoxify it ...For example, acrolein has long been known to cause cancer when its concentration in the body rises, and not much is needed to be dangerous. When a person inha...

Decisions, decisions: Male or female?

...nderstanding of infertility and even some forms of cancer and could eventually lead to the development of mo...ia the JAK/STAT pathway misfires, diseases such as cancer can result, he said. "Evolutionarily, germ cells are one of the most ancient cell types, needed by ...

Study: Harmless virus kills some cancers

... kill cervical, breast, prostate and squamous cell cancer cells in laboratory cultures, according to Penn St... has no known ill effects, kills multiple types of cancer cells yet has no effect on healthy cells," said Craig Meyers, Ph.D., professor of microbiology and i...

Scientists turn tobacco against cancer

... protein missiles -- that can target and hunt down cancer cells. The plants promise to provide a cheaper, fa...rted DNA coding for an antibody against colorectal cancer into tobacco plants. The plants, in turn, become factories churning out antibody. The report appears...

Unraveling a stomach cancer puzzle

... and identified a potential new target for stomach cancer therapy, according to a paper published today in t...mach cell growth, called TGF beta, and this allows cancer formation, and this mechanistic link is a world-first. Also, the gene differences identified in huma...

Unexpected lock and key mechanism found for the assembly of tumor blood vessels

...archers currently are conducting tests with breast cancer patients to see if measuring the activity of the r...r "lock," called integrin, could help diagnose the cancer earlier. They are also currently planning cancer clinical trials with an FDA approved drug directed ...

Researchers seek to discover what really happens when a virus enters the body

...ommon cold, to herpes, to AIDS. Even some types of cancer have been linked to viruses. Prior to Matzinger's model, the common assumption was that the body's cells recognize substances or germs that do not come from within the body. The recognition triggers the immune system's attempt to eliminate the inva...

Human embryonic stem cells have the potential to develop into eggs and sperm in the laboratory

...congenital abnormalities, infertility and possibly cancer (in particular testicular cancer). By developing suitable tests with embryonic stem cells as they differentiate to germ cells we can investigate the action of these chemicals in the laboratory. "Ultimately it might be possible to produce sperm and e...

Improving the potential of cancer vaccines

... immune suppression that stymies attempts to fight cancer with a vaccine, said researchers at Baylor College...trials with these special ligands in patients with cancer can get underway quickly. "It could have a huge impact on cancer therapy or treatment of infectious...

Study shows how retinoic acid enters a cell's nucleus

...g has important implications for the fight against cancer and other diseases. The research, which appears in a recent issue of the journal Molecular Cell (Vol. 18, No. 3), explains for the first time how the cancer-fighting vitamin A derivative retinoic acid (RA) gains entry into a cell's nucleus. When vi...

Multi-species genome comparison sheds new light on evolutionary processes, cancer mutations

...bnormalities most frequently associated with human cancer are far more likely to occur in or near the evolut... breakage hotspots may activate genes that trigger cancer and/or inactivate genes that normally suppress cancer. However, they emphasize that far more work re...

Men Estimate Men's Risks Of Common Disorders Higher Than Women Do, And Vice Versa

...ht more likely to have accidents and women to have cancer and mental illness. Accidents: 48 per cent of males compared to 37 per cent of females said men were more likely to have accidents; 58 per cent of females chose 'both', compared to 50 per cent of males. Cancer: around two thirds of both sexes said t...

USC researchers determine mechanism of action of chemotherapy drug

...nufactured by Pharmacyclics, Inc.) works to thwart cancer cells by disrupting key enzymes involved in cellul...creases in the amount of zinc available inside the cancer cells, and because zinc is involved in protein structure and function, leads to inhibition of enzyme...

New mitochondrial DNA gene chip may be early cancer diagnosis tool

...highly sensitive methods of analysis to detect the cancer indicators against the background of natural varia...s are a promising research tool for early clinical cancer diagnosis that may be faster, easier to interpret, and provide higher throughput than other methods....

Hepatitis C responds best to combo of ribavirin and interferon, study concludes

... If untreated, it can lead to liver failure, liver cancer and death. According to the Centers for Disease Control and Prevention, 170 million people worldwide are infected with HCV, and in the United States, alcoholic liver disease and chronic hepatitis C are the leading causes of cirrhosis. An additional ...

Most common lung cancers may begin in newly discovered cells

The most common form of lung cancer may begin in a group of newly isolated lung stem c... the cells could lead to earlier diagnosis of lung cancer in people. Lung cancer is the leading cause of cancer-related death in the United States, in part be...

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