Penn researchers link cell's protein recycling systems
...hallenges this thinking by showing that one system can be induced to compensate for the other. Cells are ...een the systems. We think that this molecular link can be used to benefit a wide variety of neurodegenerative diseases because accumulation of toxic protei...Bacteria ferry nanoparticles into cells for early diagnosis, treatment
... Purdue University have shown that common bacteria can deliver a valuable cargo of "smart nanoparticles" ...g. "Because the bacteria and nanoparticle material can be selected from many choices, this is a delivery system that can be tailored to the characteristics...Herpes virus hijacks DNA repair process
...of Medicine in St. Louis identified a protein that can trick the mouse cell into turning on the DNA damage response. They also showed that Epstein-Barr virus, a human herpes virus, has a similar protein. Scientists found that blocking murine herpes virus from activating the DNA damage response caused vir...Study finds mix of disease processes at work in brains of most people with dementia
...ible Alzheimer’s disease. “We know that people can have Alzheimer’s pathology without having symptoms...e whether interventions for cardiovascular disease can prevent or slow the progress of Alzheimer’s disease. On-going trials cover a range of interventions ......ure’s most abundant sugar, to HFM, a chemical that can be broken into components for products now made fr...lvents and metal halides combinations to see if he can increase HMF yield from glucose while reducing separation and purification cost. “The opportuniti...454 sequencing identifies HIV drug resistance at early stage
...ay miss many low-level resistant HIV strains which can grow rapidly under drug selection pressure and lea...on the study. “In the future, hopefully clinicians can use this knowledge to choose better antiretroviral drug combinations that have the ability to suppre...Exploring the dark matter of the genome
...ew patterns of transposons were found in each. "We can see intact transposons moving from one position to the next." Says Smith, "The heterochromatin is where transposons may be actively regulated -- they go in, get stuck, and get chopped up. Other researchers have shown that small interfering RNAs ...Cancer stem cells similar to normal stem cells can thwart anti-cancer agents
...ding to Dr. Donnenberg, the very fact that cancers can and do relapse after apparently successful therapy indicates the survival of a drug-resistant, tumor-initiating population of cells in many types of refractory cancers. “Because of the similarities between the way that normal stem cells and cancer st...Marine phytoplankton changes form to protect itself from different predators
...of saltwater algae – also known as phytoplankton – can change form to protect itself against attack by pr...certainly surprising that a single-celled organism can chemically sense the presence of nearby consumers, identify those consumers and change in opposing w......inal circumstances, many of Australia’s beekeepers can only afford a momentary sigh of relief. Asian bees (Apis cerana) are capable of carrying two types of Varroa mite – destructor and jacobsoni; the latter would not threaten the health of local bee populations but destructor has wiped out commercial...Staphylococcus aureus hides out in cells
...d persistence remain largely unknown. The bacteria can generate relapsing infections even years after the first episode was apparently cured. “S. aureus intracellular survival appears related to its capability to adopt a discrete behaviour instead of actively duplicating,” says Patrice Francois, a Gen...Research finds that circadian rhythms dominate all life functions
...d to regular periods of day and night. Oscillation can become chaotic in states of consistent lighting or...a "finely orchestrated" system and gene expression can be impacted by daylight and darkness -- or a lack of both. For example, while gene expression oscill...Potent possibilities for parasite attack
...study we have narrowed the search to a number that can be realistically studied," commented Dr Matt Berriman, senior author on the paper, from the Wellcome Trust Sanger Institute. The researchers found only five genes in the L. major genome for which no trace could be found in the other two species. B...Runners -- Let thirst be your guide
... during endurance exercise activities, and that it can be prevented by limiting fluid intake while exerci...nce exercisers drink more fluid than their kidneys can excrete. The hormone that determines how much fluid a kidney can excrete is arginine vasopressin (AV......f DNA in the human genetic blueprint, yet diseases can result not only from mutant genes, but from mutati...anisms. Genes typically have 50,000 base pairs but can range in size from a few thousand to 300,000 base pairs, Capecchi says. The genes include only a...Potato wart eyed as risk to potato production
...ng from zero-tolerance regulations for potato wart can be devastating to growers. Indirect economic losse...stricted. Spores released from infected plants can make soil unsuitable for potato production for decades. The long-term survival of fungal spores and ...UCF nanoparticle offers promise for treating glaucoma
... device for treating glaucoma, an eye disease that can cause blindness and affects millions of people worldwide. “The nanoparticle can safely get past the blood-brain barrier making it an effective non-toxic tool for drug delivery,” sa...Researchers demonstrate way to control tree height
...es. This is a “proof of concept” that tree height can be readily controlled by genetic engineering techn...ery industries, experts say, if regulatory hurdles can be overcome – a big “if.” The findings were recently published in the journal Landscape Plant Ne...Blood-brain barrier breached by new therapeutic strategy
...at a short protein (peptide) from the rabies virus can carry a strip of therapeutic material into the bra...ese experiments demonstrate how the rabies peptide can be used to deliver antiviral siRNA across the blood-brain barrier and into nerve cells in the brain....Weizmann Institute scientists develop a general 'control switch' for protein activity
... tasks within cells. Since malfunctioning proteins can cause disease, the study of protein structure and function can lead to the development of drugs and treatments for numerous disorders. For example, the discovery o...