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Tag: "bypass" at biology news

University of Pittsburgh School of Medicine researchers develop 'off-the-shelf' vascular grafts

...e the most commonly used graft for coronary artery bypass grafting even though a significant percentage of vein grafts eventually fail. Arterial grafts are the preferred conduits because they are less prone to becoming obstructed. However, they are in very limited supply, as many patients require multiple g...

Percutaneous aortic valve replacement safe, successful in high-risk patients

...uring the procedure, the patients were placed on a bypass pump for an average of 30?0 minutes to minimize blood flow through the aorta and ease placement of the replacement valve. All 17 patients survived the procedure. One patient died 5 days later from stroke. Five additional patients died after disch...

Scientists genetically engineer tomatoes with enhanced folate content

...racticed," Gregory said. "Theoretically, you could bypass this whole problem by ensuring that the folate is already present in the food." Will doctors be recommending a healthy dose of salsa for would-be pregnant women anytime soon? Probably not, the researchers say. "It can take years to get a geneti...

In obesity, brain becomes 'unaware' of fat

...trategies designed to inhibit SOCS-3 may therefore bypass leptin resistance in obese animals to restore energy balance, according to the researchers. In most adults, body weight is relatively constant despite large variations in daily food intake and energy expenditure, Cowley explained. Energy balance i...

Cancer-killing invention also harvests stem cells

...ed beneath the skin. Some of the blood flow would bypass the capillary bed and instead go into the shunt, which could remain implanted for many weeks, continually removing and killing cancer cells. King's first targets are colorectal cancer and blood malignancies such as leukemia....

UW launches study testing adult stem cells for heart damage repair

...s (such as angioplasty, stents, or coronary artery bypass surgery) to improve blood flow to the heart. UW Hospital and Clinics is one of 15-20 research sites nationwide participating in the study, which is sponsored by the Cellular Therapies business unit of Baxter Healthcare Corporation. Baxter technolo...

Does God answer prayer? ASU research says 'yes'

...erapeutic effect of intercessory prayer in cardiac bypass patients. “But, this research suggests otherwise. This study enables us to look at the big picture. When the effects of prayer are averaged across all 17 studies, controlling for differences in sample sizes, a net positive effect for the prayer gro...

Nanoparticles can track cells deep within living organisms

...or to repair blood vessels after a heart attack or bypass surgery. Tracking nanoparticle-labeled cells used in such treatments by MRI imaging would allow physicians to monitor the treatment's success or failure. The nanoparticles ?called "nano" because they measure only about 200 nanometers across, or 5...

Protein averts cell suicide but might contribute to cancer

...ave discovered how an unusual protein helps a cell bypass damage when making new DNA, thereby averting the c...he rest remains. Cells use Y-family enzymes to bypass that remaining damage when making new DNA prior to cell division, thus forcing these enzymes to copy...

Performing surgery on a beating heart may be safer

...iew of the latest clinical trials, coronary artery bypass surgery performed on a beating heart, without the ...tion that leads to fewer negative side effects for bypass patients. This review is featured in Journal of Cardiac Surgery. “Previously, it was more common f...

Fast test for low blood flow in dogs detects early heart trouble

...erify if treatments with drugs therapies, surgical bypass or stented arteries have worked to improve blood flow." Lardo, a biomedical engineer who specializes in so-called perfusion imaging, says the tiny size of blood vessels, many no bigger than 0.5 millimeters in diameter, often makes it difficult for ...

Insulin receptor stops progression of Alzheimer's disease

... However, by administering PPAR, they were able to bypass the defects in insulin signaling and preserve the cells that need insulin to thrive. PPAR molecules go directly to the nucleus of cells and tell DNA to turn on or off genes that are normally regulated by insulin, thus preventing them from dying and a...

For super-obese patients, duodenal switch beats gastric bypass

...ced greater weight loss than the Roux-en-Y gastric bypass (RYGB) by all measures in patients with a body mas...itch might provide better weight loss than gastric bypass in super-obese individuals," said Prachand. Several studies have demonstrated higher rates of weigh...

Minorities, uninsured less likely to receive care at high-volume hospitals

... abdominal aortic aneurysm repair, coronary artery bypass grafting, carotid endarterectomy, esophageal cancer resection, hip fracture repair, lung cancer resection, cardiac valve replacement, coronary angioplasty, pancreatic cancer resection, and total knee replacement. According to this database, a total...

Ultra low-dose estrogen shown safe for post-menopausal women

...g or other adverse side effects. With a patch, you bypass the liver and go straight to the blood." Yaffe notes that since the WHI results were announced in 2004, "the field of estrogen research has been stymied. Hopefully, this study will start to turn the tide." ...

Mutation in blood stem cells provides clues to cancer development

... in the JAK2 signaling pathway allows the cells to bypass the body's usual mechanism of red blood-cell production, the binding of the hormone erythropoietin (EPO) to its receptor, a process which normally regulates the production of red blood cells. As a result of this intrinsic defect, the bone marrow pro...

Heparin prepared synthetically could replace animal-derived drug

...ures and treatments such as kidney dialysis, heart bypass surgery, stent implantation, indwelling catheters, knee and hip replacements, and deep vein thrombosis. The annual worldwide sales of heparin are estimated at $3 billion. "We have synthetically prepared heparin in quantities large enough for use in ...

Therapeutic prospects beyond Vioxx

...f a new generation of anti-inflammatory drugs that bypass this issue, as reported in the April 13 advanced online edition and May print issue of The Journal of Clinical Investigation. "Although these results are in mice, not people, they raise an exciting possibility which can be tested in humans," says se...

Potential heart benefit found in stem cells

...oration of stem cells derived from new sources may bypass some of the debate that is preventing research progress right now," said Sharon A. Hunt, M.D., Stanford University. "The research presented here is extremely promising, and should be followed by more in-depth and patient-focused studies to determine...

Research details how a virus hijacks cell signals to cause infection

...es elaborate methods that the virus has evolved to bypass the body's defenses. "This study helps to explain how group B coxsackieviruses infect cells," said Jeffrey M. Bergelson, M.D., a pediatric infectious diseases specialist at The Children's Hospital of Philadelphia. "We found new steps in the virus li...

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