Studies reveal methods viruses use to sidestep immune system
... Those immune defenses should fight off the virus, but in a separate study, scheduled to appear online this week and in an upcoming issue of the Proceedings of the National Academy of Sciences, the researchers show how HCV sidesteps the immune response, allowing the virus to replicate unchecked. Dr. Mic...Development of portable infectious disease detector
...erably larger than comparable lab-on-a-chipsystems but it is also much less expensive. "That's one of theappealing features about Pria's approach," says Wikswo, "They keeptheir microfluidics and microelectronics as simple as possible.""Pria's first product focused on fertility," says VIIBRE projectengine...Researchers add new tool to tumor-treatment arsenal
...es of DNA-damaging agents to guarantee cell death, but without the toxic side effects. The researchers studied the results of combining a DNA-damaging agent called cisplatin with RAD001, a derivative of the immunosuppressive drug rapamycin. Used in organ transplant patients, rapamycin and its derivative...Why do insects stop 'breathing'? To avoid damage from too much oxygen, say researchers
..., our bodies have to supply oxygen to our tissues, but they must also keep out excess oxygen to prevent o...not only how much carbon dioxide the moth released but also the concentration of oxygen in its trachea, the series of tubes that carry air directly to cell...Scientists discover unique microbe in California's largest lake
...es of blue-green algae calledAcaryochloris marina, but different from any found in other higherplants or ...ble light to produceoxygen through photosynthesis, but now we know there are at least threeorganisms that can do this using infrared radiation as well."All...Potential Cure for Lymphoma in HIV patients
...ndard of care for patients with relapsed lymphoma, but not forpatients who suffer from both this disease ...rd-dose frontline chemotherapy for their lymphoma, but themajority either failed to achieve a complete remission or had relapsedafter an initial remission....Deficiency of growth hormone and IGF-1 reduces cancer and kidney disease, but creates other problems
...may reduce cancer and kidney disease late in life, but also may lead to cartilage degeneration and impaired memory and learning ability, according to research at Wake Forest University Baptist Medical Center and four other institutions. The researchers used a rat model to explore the effects of growth h...HIV Infection Still On The Rise
...son for this continuing increase is socioeconomic, but the increase also represents a failure of prevention, write the authors. For instance, the search for a vaccine against HIV has so far produced only negative results, while microbicides have proved disappointing. Although the ABC message (abstinence...Research Gives Hope For Liver Damage
...group of macrophages causes scarring to the liver, but the next wave ofimmune cells, produced only a few ...age, liver tissue."He added: "Cirrhosis, commonly, but not always, caused by alcoholconsumption, can lead to liver failure. At a time when outcomes forothe...New SARS Protein Linked To Important Cell Doorway
... don't have any hard evidence of orf7a's function, but they speculate that the protein's positioning coul... "We learned that the virus does make the protein, but we also got a big surprise when we looked at where the protein was," says Diamond. "Based on our ana...MSI releases 'moleculizer' - a new approach to simulation of intracellular biochemical networks
...roblem could onlycome from one with his strengths, but the work is important because itaddresses a problem arising directly from the biology."Dr. Daniel Gillespie, a pioneer in stochastic methods for modelingchemical kinetics stated, "Dr. Lok has succeeded in adapting andcreatively extending earlier deve...An entropy-based gene selection method for cancer classification using microarray data
...ising approach; yet the selection of non-redundant but relevant genes is difficult. The selected gene set should be small enough to allow diagnosis even in regular clinical laboratories and ideally identify genes involved in cancer-specific regulatory pathways. Here an entropy-based method is proposed th...Jumping gene helps explain immune system's abilities
...called antibodies that bindto particular antigens, but the early steps of that process have beendifficult...r tothat of diners creating a meal at a cafeteria, but how the immunesystem's 'a la carte' process happens is still murky," says Craig.But the a la carte a...UCSD Discovery Shows How Embryonic Stem Cells Perform 'Quality Control' Inspections
...called antibodies that bindto particular antigens, but the early steps of that process have beendifficult...r tothat of diners creating a meal at a cafeteria, but how the immunesystem's 'a la carte' process happens is still murky," says Craig.But the a la carte a...Scientists document complex genomic events leading to the birth of new genes
...otal of 22 genes with more than one copy in humans but only a single copy in all other species tested. Th...ng gene is present in all sequenced animal genomes but not in other eukaryotes, such as plants or fungi. The new gene family characterized by Dr. Bork and...New therapy for HIV/AIDS eliminates needles and excessive toxicity
...called antibodies that bindto particular antigens, but the early steps of that process have beendifficult...r tothat of diners creating a meal at a cafeteria, but how the immunesystem's 'a la carte' process happens is still murky," says Craig.But the a la carte a...Nano-Probes Allow an Inside Look at Cell Nuclei
Nanotechnology may be in its infancy, but biologists may soon use it to watch the inner work... "We knew we could get quantum dots inside a cell, but getting them through the nuclear membrane is very difficult," says Chen. "So we learned from the vir...DNA Recombination and Repair—A New Twist to RecA Function
...TP hydrolysis causes the release of RecA from DNA, but the exact rate of RecA dissociation is not known. Experiments suggest, however, that RecA molecules only dissociate from DNA when they are at the fiber’s 5' end, while ATP hydrolysis occurs all along its length. Under their experimental conditions, ...Gene sequencing explains bioremediation 'bug'
...called antibodies that bindto particular antigens, but the early steps of that process have beendifficult...r tothat of diners creating a meal at a cafeteria, but how the immunesystem's 'a la carte' process happens is still murky," says Craig.But the a la carte a......earn more not only about the dinosaurs themselves, but also about how and why they were preserved in the first place." The research was funded by NC State, the N.C. Museum of Natural Sciences and the National Science Foundation. "Soft-Tissue Vessels and Cellular Preservation in Tyrannosaurus rex" Autho...