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Tag: "but" at biology news

Chemists create 'Superbowl' molecule; May lead to better health

...ticancer drug] taxol in the near future," he says, but cautions that the superbowl molecule has not yet b... molecule will actually enter the consumer market, but any useful application is likely to take five to ten years, the researcher estimates. Administration...

DNA Molecules Used To Assemble Nanoparticles

...ds of molecules such as contrast agents and drugs, but the synthesis process is long and difficult, requiring months for each new molecule added to the dendrimer in sequential steps. And the yield of useful particles drops with each successive step of synthesis. For a paper published Jan. 21 in the jour...

Bioartificial kidney under study at MCG

...ctions develop renal failure; that's not uncommon, but it's most dreaded in the critically ill patient," Dr. Szerlip says. ...

Viral DNA sequence a possible trigger for breast cancer

... as Epstein Barr virus and Kaposi's sarcoma virus, but what role this sequence plays in cancer development has remained unexplored. Katz and colleagues now show that this sequence is contained in the Env protein of MMTV and show that expression of Env in mouse breast cells transforms them. This study pu...

New push for public health, AIDS spending at African Union summit

... be not just talk about an HIV strategy for the AU but how to tackle an action-oriented plan," Oxfam spok...ning that fighting AIDS is not just a health issue but a development issue," she said. "Now they have to deliver on the existing protocols and develop a ...

Association of herpesvirus with lung disorder questioned

...h genetic susceptibility, the investigators noted, but the pathogenesis of most cases is not known. Dr. Katano and colleagues conducted their research using a design similar to that in the earlier study: a retrospective analysis of pathology specimens from a small number of subjects. They looked for evi...

Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer

...as associated with improved breast cancer survival but not with overall survival. In this 20-year follow-up of the British Columbia trial, Joseph Ragaz, M.D., of McGill University Health Center in Montreal, and colleagues found that the chemotherapy and radiation regimen, compared with chemotherapy alon...

Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down

...as associated with improved breast cancer survival but not with overall survival. In this 20-year follow-up of the British Columbia trial, Joseph Ragaz, M.D., of McGill University Health Center in Montreal, and colleagues found that the chemotherapy and radiation regimen, compared with chemotherapy alon...

Jump-starting T Cells In Skin Cancer

...ific T cells, on the other hand, became detectable but did not expand to large numbers. Thus, reinvigoration of existing tumor-specific T cells after vaccination did not require large numbers of vaccine-specific T cells. Although it is not known how these tumor-specific cells get activated, Coulie think...

Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

...body's synthesis of triglycerides and cholesterol, but the molecular chain of events from eating fats to ... fats not only raise LDL levels in the bloodstream but lower high-density lipoproteins (HDL, or "good" cholesterol) and may have even stronger adverse effe...

A new mechanism of regulating RNA degradation

...rrectly transcribed or otherwise problematic RNAs, but investigators now know that it plays a major role ...on. "We don't yet understand how SMD is regulated but it must be," said Maquat. "Both Upf1 and Staufen1 can be phosphorylated, so their activities could b...

FDA Approves Human Hookworm Vaccine for Phase I Safety Trials

...rrectly transcribed or otherwise problematic RNAs, but investigators now know that it plays a major role ...on. "We don't yet understand how SMD is regulated but it must be," said Maquat. "Both Upf1 and Staufen1 can be phosphorylated, so their activities could b...

Spleen may be source of versatile stem cells

...velopment - includingthe formation of the spleen - but it was not known to be present inadults under norm...blood cells, a function shared by the bone marrow, but potentially toform such diverse organs as the small intestine, uterus, vascularsystem and lung. They...

Researchers discover way to make cells in the eye sensitive to light

...editary blindnessphotoreceptors are lost entirely, but the retinal ganglion cells, thecells which signal ...eir pupillary response was thesame as normal mice, but when they were exposed to bright light theirpupil constriction was incomplete.The researchers believ...

Source of molecular triggers in cutaneous T cell lymphoma identified

... of tumor viruses, of mutated genes, and of normal but usually inactive genes. The study reports that CTCL develops from a small subset of lymphocytes that are pre-programmed to respond to self-antigens exposed during normal cell death. As cells undergo the process of apoptosis, cryptic -- or masked -- ...

University of Manchester makes made-to-measure skin and bones a reality using inkjet printers

...anycomplex disfiguring of the face using CT scans, but with thistechnology we are able to build a fragment which will fit exactly. Wecan place cells in any designed position in order to grow tissue orbone."This breakthrough overcomes problems currently faced by scientists whoare unable to grow large tiss...

Enzyme, lost in most mammals, is shown to protect against UV-induced skin cancer

...iolet light is a knownsource of damage to our DNA, but under normal conditions humans andother mammals ar... UV light that cause severe sunburn in normalmice, but they also showed superior resistance to UV-induced skincancer. This work clearly points to CPD lesio...

Yellowstone microbes fueled by hydrogen, according to U. of Colorado study

... environments," Spear said. "It's partspeculation, but given the number and kinds of bacteria that aremetabolizing hydrogen, it's probably a very old form of metabolism.That's important because it tells us about the history of life onEarth," he said. "And if it works this way on Earth, it's likely tohapp...

It's not all genetic: Common epigenetic problem doubles cancer risk in mice

...GF2 stems not from a genetic problem, or mutation, but an "epigenetic" problem that improperly turns on t...ent in the mice. It doesn't cause tumors directly, but it creates an environment which is ripe for cancer to start." Because precursor cells in the colon'...

Columbia research lifts major hurdle to gene therapy for cancer

... and prostrate cancer cells, the virusentered both but only produced the toxic protein inside the cancercells. All the prostrate cancer cells died while the normal cells wereunaffected.The same virus also selectively killed human cancer cells from melanomaand ovarian, breast, and glioma (brain) tumors.Dr...

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