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Tag: "built" at biology news

Cooperation is key—a new way of looking at MicroRNA and how it controls gene expression

...rone to degradation. This inherent instability is built into the 3' tail of the mRNA in the form of noncod...cer-causing oncogenes, have these AU-rich elements built in. AU-rich element degradation involves a number of different proteins, including proteins that bi...

Turning viruses into allies against cancer

...s: Abstract 5292 A modified herpes simplex virus, built with a potent immune stimulant to thwart the spread of cancer cells, is being tested in patients with a variety of tumor types, including melanoma, breast, head and neck, and colorectal cancer. In early clinical studies, the engineered virus -- deve...

Researchers discover underwater volcano

...is that may be caused by the collapse of the newly built volcano. "It is a good idea for us to keep our eyes on this area, but there is no real reason for concern about immediate danger," said Staudigel. Three students from High Tech High in San Diego were aboard one of the two expeditions to Nafanua and...

Building a human kinase gene repository

...tion of all identified human kinase genes and have built a gene repository for this gene class. Their work is described in the online early edition of Proceedings of the National Academy of Sciences and demonstrates uses of the collection in cellular and biochemical assays. Kinases are an important class ...

Man-made wetland's effectiveness similar to natural marsh

...han would a natural marsh. The wetland, which was built in an agricultural area, reduced levels of phosphorus by nearly 60 percent and nitrates by 40 percent. Phosphorus and nitrates are prime ingredients in both fertilizers and in water pollution. High levels of these nutrients can cause algae to flouri...

Basis for DNA ejection from single phage particles

...ed. It was hypothesized that the internal pressure built during packaging of the DNA in the phage capsid was responsible for DNA ejection. This pressure results from the condensation of the DNA during morphogenesis ?for example, another group recently showed that the pressure at the final stage of encapsul...

Doing a spin with DNA

...hers has unravelled how nature releases the torque built up in DNA at the molecular level. The researchers ... The enzyme topoisomerase IB releases the torsion built up in DNA strands. During their investigations, the researchers could follow a single topoisomerase-...

wFleaBase: the Daphnia genome database

...genome sequencing projects. This new database is built primarily from core components of the Generic Model Organism Database project, and related bioinformatics tools. Over the coming year, preliminary genetic maps and the nearly complete genomic sequence of Daphnia pulex will be integrated into wFleaBa...

Gov't Creates Gene Database of Normal Human Tissues

...e, part of the National Institutes of Health, have built the largest open-source database for normal tissue...ay they constructed has more than 42,000 detectors built into two chips using verified cDNA libraries upon which many other researchers currently rely. Analy...

Butterfly migration could be largest known

...ounds, powered by a supply of yellow fat they have built up over the winter. Painted ladies migrate every year, but usually less conspicuously and in far fewer numbers. This year, however, exceptionally high winter rainfall in southern California has created a bumper crop of plants for the caterpillars to...

Internet viruses help ecologists control invasive species

...through Canadian lakes. Using network theory, they built up a picture of the lakes as nodes in a network connected by human traffic, including boat trailers and anglers. Like internet viruses, which spread fastest when they attack the most widely-used email programmes, Muirhead and MacIsaac examined patter...

Young Blood Revives Aging Muscles, Stanford Researchers Find

...ces at the Stanford University School of Medicine, built on previous work showing that old muscles have the capacity to repair themselves but fail to do so. Rando and his group studied specialized cells called satellite cells, the muscle stem cells, that dot muscle tissue. These normally lie dormant but co...

Some Brain Cells Change Channels

... a channel made of proteins called AMPA receptors, built from subunits called GluR3 and GluR4, is usually found at the synapse. If the cells are shocked with an electric current, within minutes the channels are replaced by ones made of GluR2 and GluR3. After the swap, sodium can still get in, but calcium i...

Life detection instrument passes key test on road to Mars

...new that if the Mars Organic Analyzer (MOA) they'd built could detect life in that crusty, arid land, then it would have a good chance some day of detecting life on the planet Mars. In a place that hadn't seen a blade of grass or a bug for ages, and contending with dust and temperature extremes that left ...

Grass makes environmentally friendly biofuel

... pelleted by farmers and burned in modified stoves built to burn wood pellets or corn, says Jerry Cherney, the E.V. Baker Professor of Agriculture. Burning grass pellets hasn't caught on in the United States, however, Cherney says, primarily because Washington has made no effort to support the technology w...

Researchers reveal secret of key protein in brain and heart function

...t Brown, said that knowing how a piece of SAP97 is built is an important step. Now that part of the protein's structure is solved, scientists can create a molecule to disable it. That, in turn, will allow them to fully understand SAP97's role in the body. And that will point drug makers to targets for deve...

Assessing the Amazon River's sensitivity to deforestation

...el of the Amazon River and floodplain. This model, built over the course of several years and just recently completed, simulates the inter-connected river and floodplain system for the entire 6.5 million km2 basin. According to Coe, "The problem has always been that there simply aren't enough observations ...

Scientists discover that three molecules may be developed into new Alzheimer's drugs

... genetic basis of the disease and these can now be built upon for the development of treatments. "There is no doubt that we need new approaches," said Kosik. "The insights gained about the mechanisms of the molecular and genetic basis of the disease are beginning to add up and can be harnessed for treatmen...

Scientists at Galileo Pharmaceuticals confirm inflammatory response linked to glucose levels

... genetic basis of the disease and these can now be built upon for the development of treatments. "There is no doubt that we need new approaches," said Kosik. "The insights gained about the mechanisms of the molecular and genetic basis of the disease are beginning to add up and can be harnessed for treatmen...

Promiscuous Catalytic Activity Possessed by Novel Enzyme Structure

...been found in natural sources, but the enzyme also built some new compounds that had never been seen before. The key to Orf2’s flexibility seems to reside in the active site, the region of the enzyme where the small aromatic molecules bind. In many enzymes, the structure of the active site only allows one...

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