Attacks of King George III's madness linked to key metabolism molecule
...rmittently throughout his tumultuous reign, can be brought on by fasting and exposure to certain drugs, and is successfully treated by feedings of sugar and high-carbohydrate food. A biological explanation for these nutritional effects has been lacking. The Dana-Farber scientists say in a report featured on...NIH creates nationwide network of molecular libraries screening centers
...m diverse fields of science in ways not previously brought to bear on important health problems," said NHGRI Director Francis S. Collins, M.D., Ph.D. The nine institutions receiving grants as part of the Molecular Libraries Screening Centers Network (MLSCN) are: * Columbia University Medical Center, Ne...Why were the HIV prevention trials in commercial sex workers abandoned?
...important clinical trials of tenofovir as PREP and brought negative attention to tenofovir, somewhat similar to that visited on thalidomide more than four decades ago," say two researchers in an essay in the open access global health journal PLoS Medicine. The dramatic protest at the XV International AIDS C...Hide and seek: Researchers discover a new way for infectious bacteria to enter cells
...s inward around the target to form a pocket that's brought inside the cell, creating a structure called a vesicle. "Phagocytosis and endocytosis may, in fact, be more similar than past research suggests. This is a totally new concept," Cossart says. Cossart's lab had observed that Listeria ?which is ...Gene discovery sheds light on causes of rare disease, cancer
...s inward around the target to form a pocket that's brought inside the cell, creating a structure called a vesicle. "Phagocytosis and endocytosis may, in fact, be more similar than past research suggests. This is a totally new concept," Cossart says. Cossart's lab had observed that Listeria ?which is ...Mayan stingless bee keeping: Going, going, gone?
Long before Europeans brought honey bees (Apis mellifera) to the Americas, Mayan bee keepers harvested honey from the log nests of stingless bees native to tropical forests. Now, colleagues from the Colegio de la Frontera Sur in Quintana Roo, Mexico and the Smithsonian Tropical R...Research suggests fitness of Florida panthers improved by limited breeding with Texas animals
...a new assessment. Hybrid kittens born to panthers brought into the area from Texas have "about a three times higher chance of becoming adults as do purebred ones," reports a paper planned for publication in January 2006 in the British journal Animal Conservation. "Hybrids are expanding the known range of ha...Visceral Leishmaniasis: Successful Vaccine Trial In Dogs
...s also focused on the changes to the immune system brought on by the vaccination. Laboratory experiments showed that the effectiveness of the vaccine stems from the activation of certain cells of the immune system, the T lymphocytes of type Th1. These induce the infected macrophages to produce nitric oxide, ...Sensor web simulation investigates technique to improve prediction of pollution across the globe
... firefighters, police officers, and paramedics are brought together to form and then implement a plan to find and rescue a person in need of help. Computer forecast models can also help decide where the sensors should make observations. If a model forecasts high concentrations of CO, the sensor web's instru...Computer modeling reveals hidden conversations within cells
... cell communication, to the diverse expertise they brought together. "Developing a computer model is both science and art," said Derren Barken, a graduate student in bioinformatics and experienced software engineer, who programmed the model. "It requires intuition built up over time, but it also requires...Learning how SARS spikes its quarry
...more than 8,000 people and killed 774 before being brought under control. Public health experts worry about another outbreak of the virus, which originates in animals such as civet cats. The research team, led by Howard Hughes Medical Institute investigator Stephen C. Harrison at Children's Hospital and Ha...Rutgers to lead $52.7 million protein research program
... bioinformatics. Other NIGMS pilot program centers brought the total to about 1,500 structures which can be used to model thousands of other proteins in each of the families they represent. "Already, these structures have given us new insights and allowed us to discover the functions of proteins that weren'...Metal-containing compounds show promise as HIV weapon
...rboranes they were studying to the proteases, then brought the diffraction data to UT Southwestern to have the structures interpreted. The structures were determined by a process called X-ray crystallography, in which the crystals are bombarded with X-rays, and then the patterns made when the component atoms...Oldest dated evidence of cattle in southern Africa found
...hed new light on the questions of when cattle were brought to southern Africa and from where. A domestic cow bone, dated to about 2000 years ago was excavated from a site at Toteng, located in the Kalahari Desert of northern Botswana. This bone, dated by the Accelerator Mass Spectrometry (AMS) radiocarbon te...New antifreeze protein found in fleas may allow longer storage of transplant organs
...first noticed them while cross-country skiing, and brought several samples into the lab. "It was serendipity," she says now. "They looked like dots of pepper sprinkled on the snow. Later we were able to collect large numbers for testing at the Queen's University Biological Station." Using a process called ...Careless reporting on HIV 'could cost lives'
...th activists' protests to "create a situation that brought embarrassment to the ministries". Mills says that given the role of the media in reporting on future trials, the purpose of his team's study is "not to blame the media, but to encourage [researchers] to engage with the media". Bruce Lewenstein, pro...Give thanks for the cranberry, say dental researchers
...r the cranberry sauce just to stop the tooth decay brought on by carbohydrate-laden foods like mashed potatoes, rolls, and pumpkin pie. He recommends traditional measures to avoid cavities: Brush your teeth after dinner, don't snack often, stay away from sugary foods, use a mouth rinse, and get regular denta...Breath of the dragon: ERS-2 and Envisat reveal impact of economic growth on China's air quality
...tacular economic growth during the last decade has brought many benefits - and some challenges. Global atmospheric mapping of nitrogen dioxide pollution performed by ERS-2's GOME and Envisat's SCIAMACHY reveals the world's largest amount of NO2 hanging above Beijing and northeast China, as reported in Nature...Bacterial protein mimics host to cripple defenses
...sticated tool researchers can use to knock out PCD brought on by a variety of conditions, shedding light on immunity. The protein itself or a derivative might one day be applied to control disease in crops or in people. For now, Martin and Abramovitch are working to find which proteins AvrPtoB acts on, and w...The shape of things to come: Morphology database going global
...ape and structure of plants and animals. Ronquist brought the project to FSU in 2003 when he was hired here. Besides him and Gaitros, the team includes Austin Mast and Greg Erickson of biology; Robert van Engelen of computer science; Greg Riccardi, Corinne Jorgensen and Peter Jorgensen of the College of Inf...