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Tag: "breast" at biology news

Mechanisms involved with tumor relapse identified

...tumor cells. Using a transgenic mouse model of breast cancer, researchers found that interferon gamma, a...is colleagues have been employing animal models of breast cancer to evaluate anti-tumor efficacy of a vaccine formulation they created. This vaccine formulati...

Novel antigen-cloning technique may boost efforts to develop a melanoma vaccine

...s over-expressed not only in melanoma, but also in breast cancer cells and gliomas, the most common type of ...ase. "And because the RPL8 antigen is expressed by breast cancer and gliomas, we may be able to develop a vaccine that could be used to treat these types of c...

Study to explore using magnets to correct 'sunken chest'

...t and breathing difficulties, because the abnormal breast bone can reduce blood flow to the heart and prevent the lungs from expanding completely, restricting the ability to exercise, according to Harrison. Some patients also suffer serious emotional difficulties and low self-esteem, especially since sunke...

What's in the water? Estrogenic activity documented in fish caught in Pittsburgh's rivers

... local fish can cause growth of estrogen-sensitive breast cancer cells cultured in the laboratory. Extracts ...hether the fish extracts could result in growth of breast cancer cells cultured in the laboratory, and they found that two bass extracts produced strong-to-mo...

Researchers urge monitoring of bone health during chemotherapy

...nse therapies could prolong survival in women with breast cancer. "We are not at all advocating ending G-...owth. When the researchers injected melanoma or breast cancer cells into mice, those getting G-CSF developed a two-fold increase in tumor burden, a measure...

Genes and biomarkers that allow doctors to choose the right therapy for the right patient

...erapy. Molecular predictors of drug response in breast cancer: Abstract 4963 Researchers at Lawrence...ers to predict how individuals will respond to the breast cancer drugs lapatinib and CI-1040. Their findings could help in individualizing treatments for wom...

Cancer tip -- Nanoparticles can damage DNA, increase cancer risk

...ticles could cause DNA damage in the MCF-7 line of breast cancer cells. She and her team examined the g...dent and time-dependent increases in DNA damage in breast cancer cells exposed to either aqueous colloidal silica or C60 fullerenes," Pacheco said. "The DNA ...

Selective marker found to indicate aggressive form of breast cancer

...ein called nestin to a particularly deadly form of breast cancer, identifying a new biomarker that could lea...a selective biological marker for basal epithelial breast tumors, a highly aggressive cancer with similarities to mammary stem cells, the regenerative cells b...

Growth hormone is not the anti-aging bullet for healthy adults

...ain, carpal tunnel syndrome, and, in men, abnormal breast development. They were also somewhat more likely to develop diabetes. The review, "The Safety and Efficacy of Growth Hormone in the Healthy Elderly," was published in the Jan. 16, 2007, issue of Annals of Internal Medicine and is available on t...

Inflammation may play role in metastasis of prostate cancer

...h has well-established anti-metastatic activity in breast and prostate cancers. They found that the production of Maspin is repressed by a series of events triggered by tumor inflammatory cells, with the result that prostate cancer cells spread. "An excellent inverse correlation between IKKa activation a...

Notorious cancer gene may work by destroying messenger

... is found in about half of all colon, liver, lung, breast and pancreatic tumors, and the amount of Src can be significantly higher in cancer cells compared to normal cells. Earlier research led by Schoenberg found that PMR1 helps control protein production by destroying particular messenger RNAs (mRNAs)...

Gene expression test reveals ER and HER-2 status of breast tumors

Two critical characteristics of breast cancer that are important to treatment can be iden...characteristics and vulnerabilities of a patient's breast cancer and ultimately to guide treatment. About 70 percent of breast cancers are estrogen-recept...

Scientists map key landmarks in human genome

...m several cancer cell lines including melanoma and breast cancer, as well as several normal human cell types. A critical component of the analysis involved processing the data using computational algorithms devised by Dana-Farber faculty member X. Shirley Liu, PhD, and her postdoctoral fellow Jun S. Song, P...

Molecular signature may identify cisplatin-sensitive breast tumors

...Center have identified a subgroup of hard-to-treat breast cancers that may be sensitive to the drug cisplatin, rarely used in the treatment of breast tumors. They also have discovered the molecular basis of this sensitivity, which may help identify ...

UF scientists discover new genus of frogmouth bird in Solomon Islands

...ts speckles are larger, and the white spots on its breast and underbelly are more pronounced than on other frogmouths. Two other genera of frogmouths exist: one in southeast Asia and the other in Australia and New Guinea. The Solomon Islands Frogmouth is known to inhabit three islands: Isabel, Bougainvi...

Cancer researchers add spice to research against rare neuromuscular disease

...est, finding that the spice offers promise against breast cancer, melanoma, Alzheimer's disease and the blisters that come with radiation treatments for cancer. Chang notes that ginger, a family of spices that includes curcumin, is widely used in China as a folk medicine to treat male-pattern baldness. T...

Lab research may one day lead to cancer treatment using patient's own immune cells

...alled T cells, to fight skin cancer (melanoma) and breast cancer. The research project is called "Molecular studies of T cell clones for adoptive therapy." The pre-clinical trial, which means it will be used only in human tissues in the laboratory at this stage, will focus on identifying and harvesting T...

Protein found to shield pancreatic cancer cells from self-destruction

...G2 overexpression to drug-resistant and metastatic breast cancer, pancreatic cancer and melanoma. Expression of TG2 is tightly regulated in a healthy cell, Mehta says, and is temporarily increased in response to certain hormones or stress factors. "However, constitutive expression of this protein in a ca...

Largest genomic search finds genes that may contribute to autism

...es that heighten a person's chances for inheriting breast cancer or heart disease. Autism is actually a spectrum of disorders that inhibits a person's ability to communicate and develop social relationships. It is often accompanied by extreme behavior challenges. Autism Spectrum Disorders are diagnosed ...

Antibody signal may redirect inflammation to fuel cancer

...al and colon cancer, and most likely also lung and breast cancer," she said. "If we confirm that what we've discovered in the mice studies also occurs in human cancers, we may soon be in a good position to slow this cancer process using drugs already under study for severe immune disorders." Coussens env...

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