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Tag: "breakthrough" at biology news

ASU researchers 'wire' DNA to identify mutations

...ongjian Tao and Peiming Zhang has developed a new, breakthrough technique for the detection of DNA mutations. The...t is still costly and time consuming." The team's breakthrough relies on an intrinsic physical property of DNA, conductivity, or how well the molecule can carry an...

Study finds that nutritionally enhanced rice reduces iron deficiency

...n in their blood. "This study documents a major breakthrough in the battle to prevent micronutrient malnutrition," said Dr. Robert Zeigler, director general of IRRI. "These results are especially important for rice-eating regions of the world where more than 3 billion of the world's poor and undernourished liv...

Yale scientists decipher 'wiring pattern' of cell signaling networks

... this week in the journal Nature. The study is a breakthrough in understanding mechanisms of how proteins operate in different cell types under the control of master regulator molecules called protein kinases. Although protein kinases are already important targets of cancer drugs including Gleevec and Herceptin...

Breakthrough for stem cell research

...) line without the use of any animal products. The breakthrough eliminates the risk of animal-to-human contamination in potential stem cell therapy treatments. "This is the first hESC line produced in Australia and only the second one in the world, which does not use animals in any way. Our line grows on hum...

Carbon nanotube absorption measured in worms, cancer cells

...arbon nanoparticles into worms and cancer cells, a breakthrough that will revolutionize scientists' understanding of how the particles impact the living environment. A team led by U-M chemical engineering professor Walter J. Weber Jr. tagged multi-walled carbon nanotubes---one of the most promising nanomaterial...

Rice bioengineers pioneer techniques for knee repair

A breakthrough self-assembly technique for growing replacement cartilage offers the first hope of replacing the entire articular surface of knees damaged by arthritis. The technique, developed at Rice University's Musculoskeletal Bioengineering Laboratory, is descr...

Mining for gems in the fungal genome

... 1929, scientists have scrutinized fungi for other breakthrough drugs. As reported Jan. 20 in the Journal of Chemistry and Biology, a team led by a University of Wisconsin-Madison researcher has developed a new method that may speed the ongoing quest for medically useful compounds in fungi. By manipulating a ...

Fruit fly's beating heart helps identify human heart disease genes

... gene in humans," Rockman said. "It is an enormous breakthrough to demonstrate that a human gene can induce disease in a fly. With this novel fruit fly model, we can now screen genes we believe are involved in human heart disease and test them in the fly model." If a candidate human gene leads to the same physio...

Discovery of new molecular tools for biosynthesis could lead to advances in use of pectin

...s. Now, in what has been described as a "crucial breakthrough in pectin biosynthesis," a team of researchers at ...in lowers serum cholesterol levels.) While not the breakthrough that will allow immediate manipulation of total pectin biosynthesis, it is, one of the researchers i...

Rutgers researchers find fat gene

...mation of fats ?triglycerides, specifically. The breakthrough for Carman's group grew out of work with ordinary baker's yeast; a simple single cell organism. "We isolated the PAP enzyme from yeast that corresponds in form to lipin in mammals and showed that yeast cells lacking the enzyme exhibited a 90 percent ...

Sea coral's trick helps scientists tag proteins

...of refined high-performance GFP mutants. A major breakthrough in fluorescent protein applications came when Sergey Lukyanov first found GFP-like proteins in corals, Zimmer said. Before Lukyanov, no one had looked for GFP-like proteins in corals because they do not glow in the dark like fireflies and jellyfish. ...

Basic research leads to a novel cancer therapy

...block signal transduction in tumour cells is a new breakthrough in the war on cancer. They attack critical cancer cell functions in multiple ways and are well tolerated by patients." This is the second time that Ullrich has played a leading role in the development of a successful cancer therapy. Seven years ago,...

Key heart and Alzheimer's disease protein imaged for first time in native state

...s of apolipoprotein E, commonly known as apoE. The breakthrough has already answered long-standing questions about the configuration of apoE4 in its active, or native, state. A complete understanding of the protein's functioning will be a key factor for development of future therapeutic interventions, according t...

Scientists re-engineer a well-known antibiotic to counter drug resistance

...ics was developed with the specific idea that this breakthrough technology could be used to alter and enhance their therapeutic properties," Boger said. "We hope that our pioneering efforts will spur further research into the development of more potent antibiotics." ...

FDA approves first medical device using rutgers biomaterial

...ice employing a new biomaterial represents a major breakthrough for regenerative medicine," Kohn said. The novel tyrosine-based polyarylates, as they are known chemically, arose from an adaptation of combinatorial chemistry to biomaterials. "Our approach uses two sets of starting materials that are combined with...

New weapon in battle against osteoporosis

...icular gene defect have a lower bone density. This breakthrough is making "cannabinoidreceptors" a key focus of osteoporosis research. "We know two types of cannabinoidreceptors, CB1 and CB2," explains Dr. Karsak. "The CB1 receptor is formed by nerve cells in the brain and is responsible for, among other things,...

One big biology question solved

...sperm and females produce eggs. The finding is a breakthrough that could lead to improved infertility treatment, cancer therapy and pest management. The team, led by Dr Josephine Bowles and Professor Peter Koopman from the Institute for Molecular Bioscience at The University of Queensland, has discovered that...

Spray-on skin relieves emotional trauma for child burn victims

...id the research showed Microskin was a significant breakthrough for the psychological damage of burns. "Children with burns can experience emotional difficulties as a result of physical disfigurement. This product can help alleviate these difficulties and help with a patient's overall recovery and rehabilitatio...

Carnegie Mellon researchers discover new cell properties

...is Noel Dahl and Mohammad F. Islam have made a new breakthrough for children suffering from an extremely rare disease that accelerates the aging process by about seven times the normal rate. Dahl, an assistant professor of chemical and biomedical engineering at Carnegie Mellon, said her work with researchers at ...

A switch between life and death

The breakthrough came as Barry Thompson from Stephen Cohen's group at EMBL looked at a recently discovered signaling pathway called "Hippo." "Hippo acts as a switch between cell division and death," says Barry Thompson, "If the pathway is too active, tissues overgr...

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