Researchers identify protein crucial for survival of Lyme-disease bacterium
... proteins and nutrients made available as the tick breaks down whole blood. "For some reason, bacteria lacking the BptA protein either can't utilize the blood meal in the way the wild-type bacteria do, or something about the blood becomes hostile to them," said Dr. Norgard, who holds the B.B. Owen Distingu...Increased risk of osteoporosis associated with gene that one in five people have
...enzyme that detoxifies foreign substances and also breaks down estrogen as a normal part of maintaining prop...ular variation of the gene produces an enzyme that breaks down estrogen faster than usual, leading to low serum estrogen levels and high levels of estrogen me...Unprecedented water level rise in Somalia
...capital Mogadishu, three villages were affected by breaks in the river. Overnight, river levels dropped from 4.6 to 4 metres, suggesting a breach somewhere upstream. OCHA said Somali authorities and humanitarian agencies agreed that larger scale protection of the river embankment was required and that it wo...Highly adaptable genome in gut bacterium key to intestinal health
...ies in the human gut microbial community. B. theta breaks down otherwise indigestible carbohydrates, such as dietary fiber, and supplies its host with nutrients while obtaining food for itself and other gut bacterial species. The complete genome sequence of B. theta was generated two years ago in the same l...New comparative toxicogenomics database
...nce at the other side of thecell, the pneumococcus breaks free of pIgR and enters the blood, whereit can multiply and infect the body. S. pneumoniae is the only bacterium known to use CbpA to invade humancells by binding to pIgR, according to Richard W. Kriwacki, Ph.D.,associate member of St. Jude Structur...Discovery of key protein's shape could lead to improved bacterial pneumonia vaccine
...nce at the other side of thecell, the pneumococcus breaks free of pIgR and enters the blood, whereit can multiply and infect the body. S. pneumoniae is the only bacterium known to use CbpA to invade humancells by binding to pIgR, according to Richard W. Kriwacki, Ph.D.,associate member of St. Jude Structur...Researchers identify target for cancer drugs
...t when PTEN is mutated and unable to function, Akt breaks free. It makes its way to the cell membrane where other proteins activate it, thereby enabling Akt to contribute to tumor growth. "When a cell loses PTEN through, say, a mutation, Akt goes gangbusters," says Sabatini. The exact means by which Akt sw...Newly-discovered class of genes determines ?and restricts ?stem cell fate
...can both determine the cell type, but also put the breaks on differentiation," says Epstein. "We have named them pangenes, after the Greek god Pan and Peter Pan, who were able to orchestrate complex events while never growing old." Epstein thinks that this concept may also be important for understanding th...Key molecule in plant photo-protection identified
...ar function. Holtzman suspects that this transport breaks down inthe mice, leading to pileups that become swellings. Scientists havepreviously demonstrated that such swellings make it difficult orimpossible for nerve-cell branches to send signals.After showing that the swellings were mostly stable in number...Mouse brain cells rapidly recover after Alzheimer's plaques are cleared
...ar function. Holtzman suspects that this transport breaks down inthe mice, leading to pileups that become swellings. Scientists havepreviously demonstrated that such swellings make it difficult orimpossible for nerve-cell branches to send signals.After showing that the swellings were mostly stable in number......efect, as the transport machinery in their neurons breaks down with age. "A person could have a predisposition to the disease, or it could just be that as time progresses, one person could by chance accumulate these blockages more than another," said Goldstein. "And randomly, some people would accumulate mo...