Penn researchers link cell's protein recycling systems
...ns with ubiquitin tags and shuttles them for rapid breakdown to a complicated structure called the proteasome. The second is the autophagy-lysosomal system, a more general process in which proteins are surrounded by membranes inside the cell for bulk digestion. “The dogma has been that the autophagy-lysosom......y dies within a few months from starvation and the breakdown of body functions. The integrated research team at AAHL will use a variety of techniques including microscopy, microarrays and a range of molecular techniques to search for infectious agents, markers for disease and to determine where the tumours...