Scientists discover a new risk factor for Alzheimer's
...gists, showing reduced SORL1 protein levels in the brains of patients with Alzheimer's. Then we have the observation by us and other groups that if you reduce SORL1 expression--in either cell cultures or mice--you get an increase in the production of amyloid-beta. Now we can add our new observation that var...Scientists find new genetic clue to cause of Alzheimer's disease
...oid plaques, a hallmark sign of Alzheimer's in the brains of people with the disease. They identified 29 variants that mark relatively short segments of DNA where disease-causing changes could lie. The study did not, however, identify specific genetic changes that result in Alzheimer's. Richard Mayeux, M....Tracing broken wiring in stroke patients
...eriments, the researchers used FC MRI to study the brains of 11 stroke patients with neglect, both at one mo...ix months after their strokes. While the patients' brains were being scanned, the researchers asked them to perform a simple task to determine their ability t...Study shows hope for early diagnosis of Alzheimer's
...aluating the parietal and occipital regions of the brains of 71 patients, some already diagnosed with Alzheimer’s and some without Alzheimer’s. Their diagnostic accuracy rate was 82 to 85 percent using the EEGs (e.g., it matched evaluations conducted at Penn 82 to 85 percent of the time). Alzheimer’s diseas...Cold sore virus might play role in Alzheimer's disease
... of the activity levels of the herpes virus in the brains of mice with different forms of the human ApoE gen... tangles and amyloid plaques that are found in the brains of patients with the disease. Researchers have found several ways in which the gene might make a per...Newborn brains grow vision and movement regions first
...e UNC team is that boys, on average, are born with brains about 10 percent larger than the brains of girls. This is consistent with the pattern seen in adults, Gilmore said -- men typically have a b...Stem cells act through multiple mechanisms to benefit mice with neurodegenerative disease
...were implanted -- at simply one time point -- into brains of newborn Sandhoff mice, the onset of symptoms wa...ened the inflammation that typically occurs in the brains of most degenerative diseases, including Sandhoff's, and likely contributes to disease progression. ...3 proteins may play important role in nerve-cell repair
...called GPR3, GPR6 and GPR12, on nerve cells in the brains of rats. When researchers increased the amount of the three proteins, the cells grew extensions that were up to three times longer than those on nerve cells with normal levels of the proteins, and the extensions grew four to eight times faster th...Lithium builds gray matter in bipolar brains, UCLA study shows
...sorder, increases the amount of gray matter in the brains of patients with the illness. The research is fe...ar disorder. When the researchers compared the brains of bipolar patients on lithium with those of people without the disorder and those of bipolar patien...Mimicking how the brain recognizes street scenes
...s measured in the lab is sufficient to explain how brains can perform complex recognition tasks." Making it More Useful The model used in the street scene application mimics only the computations the brain uses for rapid object recognition. The lab is now elaborating the model to include the brain's ...MIT model helps researchers 'see' brain development
...arge mammals--humans, monkeys, and even cats--have brains with a somewhat mysterious feature: The outermost layer has a folded surface. Understanding the functional significance of these folds is one of the big open questions in neuroscience. Now a team led by MIT, Massachusetts General Hospital and Harva...Action video games sharpen vision 20 percent
...rt. "Action video game play changes the way our brains process visual information," says Daphne Bavelier, professor of brain and cognitive sciences at the University of Rochester. "After just 30 hours, players showed a substantial increase in the spatial resolution of their vision, meaning they could see...Out-of-body experiences may be caused by arousal system disturbances in brain
...esults are intriguing, and show that some people's brains already may be predisposed to these sorts of experiences. They found that an out-of-body experience is statistically as likely to occur during a near death experience as it is to occur during the transition between wakefulness and sleep. Nelson sugge...Although no two brains are alike, they can display a comparable pattern of neural activity when exposed to similar sensory input. Scientists at the Max Planck Institute for Dynamics and Self-Organization in Göttingen have now developed a mathematical method to design netwo...Researchers develop marker that identifies energy-producing centers in nerve cells
...eenish-yellow glow when the scientists look at the brains of these mice through a fluorescent microscope. The researchers have determined that the expression of the fluorescent protein does not interfere with the normal functions of mitochondria. Neurons conduct and generate electro-chemical impulses or ...Proteasome activator enhances survival of Huntington's disease neuronal model cells
...easome system (UPS). In Huntington's disease (HD) brains and other tissues, UPS activity is inhibited and i...lear protein aggregates of mutant huntingtin in HD brains indicate dysfunction of the UPS. From these results, we hypothesized that enhancing UPS function wou...Digital atlases of the brains of humans, monkeys, dogs, cats, mice, birds and ot... directly accessible online. Users can explore the brains of humans and a variety of other species at an unprecedented level of detail, from a broad view of t...Revealing the machinery underlying the 'plastic' juvenile brain
... the genetic machinery of juvenile and adult mouse brains undergoing visual experience have uncovered differ...tex in each animal's brain. They found that the brains of the juvenile mice showed activation of specific genetic mechanisms that the adult brains did not....Scientists identify prion's infectious secret
... cascade creates long fibers called amyloids. (The brains of animals that have died from prion infections are literally packed with amyloid clumps.) In order to glean insights into the mechanics that enable amyloid formation, Peter Tessier, a postdoctoral scientist in Lindquist’s lab, used peptide array......en the twin towers toppled on Sept. 11, 2001, have brains that are more reactive to emotional stimuli than t...st studies to look at the effects of trauma on the brains of healthy people, it is published in the May issue of the journal Emotion. "These people appear t...