A gene's first 'kiss' sets off that affair known as puberty
...ter, builds on the discovery made independently by both Harvard and French researchers that a gene called ...o Mastronardi, Ph.D., and Sergio R. Ojeda, D.V.M., both from the division of neuroscience at the Oregon National Primate Research Center; and Stephanie B. S...Man and mouse share genome structures
...an genome. They also sampled additional regions in both the human and mouse genomes, finding similar patterns along equivalent chromosomal regions, even where the underlying DNA sequences are different. Bernstein and Schreiber began to develop the analytical techniques several years earlier, working with...Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer
...cts, including cardiac deaths, were acceptable for both groups of patients. "Our results, and those from other groups, confirm that in situations where residual disease remains, adjuvant chemotherapy alone in high-risk breast cancer patients is suboptimal and that the addition of locoregional radiation t...Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down
...cts, including cardiac deaths, were acceptable for both groups of patients. "Our results, and those from other groups, confirm that in situations where residual disease remains, adjuvant chemotherapy alone in high-risk breast cancer patients is suboptimal and that the addition of locoregional radiation t...Spleen may be source of versatile stem cells
...ng the embryonicdevelopment of mammals.The finding both supports the existence of these splenic stem cells andalso suggests they may be able to produce an even greater variety oftissues. The report appears in the January 19 issue of SAGE KE , an online resource on the science of aging from the publishers...UCSB scientists probe sea floor venting to gain understanding of early life on Earth
...explains that subseafloor ecosystems may represent both the cradle of life on Earth and a model for the exploration and discovery of life on other planets. "We are highly conscious of the importance of microbes in the grand scheme of things," said Haymon. "Indeed, they are the greatest biomass on the pla...W.M. Keck Foundation funds study of friendly microbes
...h and preventing or treating a variety of diseases both inside and outside of the gastrointestinal tract." ...It's not all genetic: Common epigenetic problem doubles cancer risk in mice
...s were normal. The tumors grew at the same rate in both sets of mice, suggesting that more tumors get star...tional Institute on Aging notes that the mice with both double IGF2 and the APC mutation should be a useful animal model to evaluate the impact of colon can...Columbia research lifts major hurdle to gene therapy for cancer
...ormal and prostrate cancer cells, the virusentered both but only produced the toxic protein inside the cancercells. All the prostrate cancer cells died while the normal cells wereunaffected.The same virus also selectively killed human cancer cells from melanomaand ovarian, breast, and glioma (brain) tumor...Novel technology detects human DNA mutations
...gy can rapidly, easily, and accurately interrogate both bases in the pair to determine if they are homozygous (i.e., both are mutant or normal) or heterozygous (i.e., one is mutant, one is normal) ?the most critical step i...Topical treatment shown to inhibit HIV and herpes simplex virus infection
...gel applied in the vagina provides protection from both the human immunodeficiency virus (HIV) and the her...ined after the application of PRO 2000 gel reduced both HIV and HSV infectivity by at least 1000-fold compared to CVL obtained at baseline. The effects were...Priming embryonic stem cells to fulfill their promise
... stem cellsthey tested. Unexpectedly however, when both collagen-1 and fibronectinwere combined in one niche, the liver cell differentiation rate wassubtly inhibited. "You would not predict that from the customary cellbiology experiments," said Bhatia. "By using this combinatorialtechnique we were surpris...Growth in the sea comes down to a struggle for iron
...rking to assist their Japanese colleagues on board both vessels, they made these measurements to characterize how the phytoplankton responded to the iron enrichment over a 32-day period. They also ran experiments on deck to learn how available the iron was in the patch, how diatoms were growing and coming...New, automated tool successfully classifies and relates proteins in unprecedented way
... a protein's location in a cellimage. SLFs measure both simple and complex aspects of proteins, suchas sha... was developed by Jonathan Jarvik and PeterBerget, both associate professors of biological sciences at CarnegieMellon. The computational analyses were carri...Lack of enzyme turns fat cells into fat burners
... andglucose in cultures of fat cells isolated from both normal and mutantmice that lacked ACC2. When the mice were fed a normal diet, fatty acidoxidation was 80 percent higher in the fat cells of the mice lackingACC2 when compared to normal mice. When they were fed a high fat, highcarbohydrate diet for fo...Fox Chase Cancer Center scientists identify immune-system mutation
....; and Weihong Xu, Ph.D., and Bruce A. Roe, Ph.D., both of the University of Oklahoma's department of chemistry and biochemistry. ...Current human embryonic stem cell lines contaminated UCSD/Salk team finds
... these are also derived fromanimal products," said both papers' senior author Ajit Varki, M.D.,UCSD professor of medicine and cellular & molecular medicine, andco-director of the UCSD Glycobiology Research and Training Center.The research in Nature Medicine was done with human embryonic stemcells grow...Newly-discovered class of genes determines ?and restricts ?stem cell fate
...ool of Medicine. These genes ?dubbed pangenes ?can both govern a stem cell's fate and put a hold on future...ually new since he suggests that a single gene can both tell a cell what it should become and restrict its fate by preventing differentiation. The ability o...Plants, animals share molecular growth mechanisms
...ry, has opened a scientific toolbox to learn about both plant and animal development, according Purdue Uni...cellular life evolved, they have been conserved in both plants and animals, Szymanski said. So, some of the plant proteins that comprise the ARP2/3 and the ......ant in very similar ways. The plant's responses to both friend and foe are also remarkably similar. Using...otus japonicus responded similarly to signals from both rhizobia, the friends that fix nitrogen for the plant, and root-knot nematodes, the parasitic foes t...