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Tag: "boosted" at biology news

Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial

...ombining the FAK-silencing liposome with docetaxel boosted tumor weight reduction to the 94-98 percent range. These results also held up in experiments with ovarian cancer cell lines resistant to docetaxel and to the chemotherapy drug cisplatin. The FAK-silencing liposome and the liposome with chemot...

Acidity in the brain could hold the key to stroke treatment

...r detecting brain damage caused by stroke has been boosted up by a £1m grant to scientists at The University of Manchester. Professor Gareth Morris of the School of Chemistry and Professor Risto Kauppinen of the University of Birmingham are to lead the development of a new non-invasive technique which measur...

Researchers find docking sites for glucocorticoid receptor and Hsp90

... Finding and confirming the two binding sites were boosted by the recently published crystallized structures of both Hsp90 and GR, Darimont said. "Our results suggest that Hsp90 binds GR with the help of specific docking sites in the C-terminal domain of Hsp90," she said. "This finding opens the possibili...

'Erectile dysfunction' drugs heighten natural anti-cancer activity

...al of Experimental Medicine, the Hopkins team says boosted levels of the chemical messenger nitric oxide appear to dampen the effects of a specialized cell that diverts the immune system away from tumors, allowing swarms of cancer-attacking T-cells to migrate to tumor sites in the rodents. Lab-grown canc...

US conservation efforts bring more marine turtles to UK

US and Mexican conservation efforts may have boosted the number of marine turtles visiting UK waters, according to University of Exeter biologists. New research by the University of Exeter and Marine Environmental Monitoring, published this week in Marine Biology (3 May 2007), analyses 100 years of d...

Common gene version optimizes thinking -- but with a possible downside

...cts had the most common version of the gene, which boosted circuit activation, structural and functional connectivity and performance on thinking tasks, likely by increasing gene expression. In 257 affected families, people with schizophrenia were more likely to have this common version of the DARPP-32 gene....

Stem cells act through multiple mechanisms to benefit mice with neurodegenerative disease

...into a diseased brain. The transplanted cells also boosted the brain's supply of the enzyme Hex, which reduced the lipid accumulations in the treated animals. The experimental treatment also dampened the inflammation that typically occurs in the brains of most degenerative diseases, including Sandhoff's, and...

Salk scientists hammer out a pathway that promotes muscle cell survival in mice

...was also reduced. Conversely, when the researchers boosted SIK1 levels or inhibited HDAC activity with a drug, muscle cell health was restored in mice genetically engineered to lack CREB and suffering from muscle weakness as a result. "We’ve discovered that SIK1 provides a completely unexpected link ...

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