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Tag: "bone" at biology news

Finding paves way for better treatment of autoimmune disease

...l of graft versus host disease, a problem for some bone marrow transplant patients when immune cells from the donor start attacking. This finding indicates a potential role for helping transplant patients keep new organs, the researchers say. Dr. Iwashima has an Alcoholic Beverage Medical Research Found...

Combined treatment extends life expectancy for lung cancer patients

...red the use of RFA in thyroid, kidney, adrenal and bone cancer. The combined treatment may have far-reaching effects, Dupuy says. "You might be able to treat tumors elsewhere in the body with similar results," Dupuy says. "There are a lot of opportunities for exploring the synergy of thermal ablation an...

Failure of 'scout cells' may lead to cancer in transplant patients

...ney transplant patients and in up to 20 percent of bone marrow and lung transplant patients. The disease usually arises within six months to a year after transplantation, and it can have a 70- to 80-percent mortality rate. The study by VanBuskirk and her colleagues examines two types of immune cells: c...

Gatekeeping: Penn researchers find new way to open ion channels in cell membranes

...ed non-excitable cells (such as immune, blood, and bone cells) whose membrane voltage stays largely constant, as opposed to the excitable cells whose membrane voltage constantly varies in a precisely controlled manner. How the activity of channels in non-excitable cells is regulated has been a long-stand...

Protein-coated dental implants could improve bone regeneration

...m dental implants coated with proteins that induce bone formation may be a key advancement in treating too... in MCG's School of Dentistry. Loss of teeth and bone is a common and devastating result of gum disease. Dr. Wikesjö, who came to MCG this year from Tem...

Injection may prevent infertility in men receiving cancer chemotherapy

...had already shown that AS101 could protect against bone marrow damage and hair loss, and also sensitises the tumour to treatment", he said. The scientists divided the mice into four groups ?Taxol only, AS101 plus Taxol, AS101 only, and a control group. After 30 days they were euthanized and their teste...

Can you hear me now? Scientists find previously unknown receptors on adult stem cells

...years, researchers believed that stem cells in the bone marrow spent most of their existence in a slumber-...s that are vulnerable toinfections after receiving bone marrow or cord blood transplants or inautoimmune diseases like lupus, where immunosuppressive treatm...

Adult stem cells are touchy-feely, need environmental clues

...enchymal stem cells, which regularly reside in the bone marrow as part of the body's natural regenerative mechanism, depend on physical clues from their local environment in order to transform into different types of tissue. The researchers were even able to manipulate stem cells by changing the firmness...

Matrilin-3 gene discovered to prevent onset of osteoarthritis

...ospital. The matrilin-3 gene plays a role in early bone development, controls bone mineral density in adulthood and prevents osteoarthritis later in life. Mutations in matrilin-3 h...

Bones hold the key to blood renewal

...findings, which may lead to future improvements in bone marrow transplantation and a better understanding of diseases involving bone or blood renewal, were published in the June issue of Nature Medicine. Bones are really two syste...

Research identifies protein in mice that regulates bone formation

...oporosis, a disease characterized by a decrease in bone mass and density and which makes people more susceptible to bone fractures and deformities, afflicts some 10 million Americans over the age of 50. Researchers at the...

How can identical twins be genetically different?

...ages joints. RA causes pain, loss of movement, and bone deformities. It affects 2.1 million Americans. There are many genetic factors that put people at a high-risk for developing RA, yet only 15 percent of identical twins will both develop it. Scientists compared gene expression patterns of 11 pairs o...

First human study confirms that immune cells can be a primary cause of bone loss in gum disease

... researchers had suspected the correlation between bone loss in periodontal (gum) disease and immune cells...e to determine methods for intervening and halting bone loss and thus improving the health outcomes of the estimated 80 million Americans suffering from per...

New MRI technique quickly builds 3-D images of knees

... the new technique - suppressing the fat signal in bone provides image contrast between bone and the cartilage surface. The conventional data-acquisition method would spend half its scan time s...

New genes implicated in rheumatoid arthritis

... steroid pathway enzyme linked to inflammation and bone erosion. This gene was also found over-expressed in the synovial tissue of OA patients. The third most significantly over-expressed gene was cysteine-rich, angiogenic inducer 61 (Cyr61), well-established for its role in the formation of new blood v...

U of M study examines kidney stone prevention in astronauts

...nauts have exercised in space to attempt to combat bone loss, the lack of gravity makes it difficult to achieve enough resistance to maintain their pre-flight fitness levels. "This becomes a real health concern, as the time astronauts spend in space and living in the space station is extended," said Mano...

New pathways for autoimmune treatment identified

...ewer i NKT cells in the thymus, spleen, liver and bone marrow and severely impaired maturation of those c...s watched the key regulatory cells come out of the bone marrow and go to the thymus where all T cells go for a process of positive and negative selection an...

U of MN uses robotic surgery techniques in cardiac cell therapy research

...lled in clinical research trials." Skeletal and bone marrow cells that are injected into damaged heart tissue have been shown to improve function in the left ventricle, the chamber of the heart that pumps blood into the aorta, the main artery through which oxygen-rich blood flows from the heart to the ...

Heat-shock protein vaccine reduces alveolar bone loss

...date to inhibit multiple bacteria-induced alveolar bone loss.Recombinant P. gingivalis HSP60 was produced ...ith P. gingivalis HSP60, and experimental alveolar bone loss was induced by infection with multiple periodontopathogenic bacteria. There was a very strong ...

Alaska seal pup diet may hold key to decline of population

...ently and eliminating needed nutrients. Measuring bone growth to see if one group grows more quickly. Monitoring the concentrations of cortisol, in response to a stressor that dilates the pupils and increases heart beat. Animals in the low fat group may take a longer time to recover. Comparing their d...

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