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Tag: "bone" at biology news

Molecular 'marker' on stem cells aids research, perhaps therapies

...ify adult stem cells for use in therapies aimed at bone healing, tendon repair and cartilage regeneration,... was found on the surface of certain stem cells in bone marrow that give rise to fat, cartilage and bone. These so-called mesenchymal cells are a tiny compo...

Smashing the time it takes to repair our bones

...nology is helping scientists better understand how bone cells work and may one day lead to the development...nne Hannay has built a gadget capable of promoting bone cell formation in the laboratory. Dr Hannay said his device replicated the mechanical and electri...

Bones at the nanoscale

... way deformation at the nanoscale takes place in a bone by studying it with the synchrotron X-rays. This s...published this week in the PNAS online edition. A bone is made up of two different elements: half of it is a stretchable fibrous protein called collagen an...

Lost in the labyrinth

...articular kinds of stem cells disappeared from the bone marrow of the mice. Others were too frequent. Bone...before they leave the stem cell compartment in the bone marrow, something so far not thought to occur. The study proves that beta-catenin plays a central r...

Intravenous gene therapy protects normal tissue of mice during whole-body radiation

...se plasmid liposome (MnSOD-PL) gene therapy on the bone marrow during whole-body irradiation. The researchers found that in a control group of mice that received an initial 9 Gy dose of radiation there was 80 percent survival at 30 days compared to 93.3 percent survival during the same length of time for ...

Vaccination with embryonic stem cells prevents lung cancer in mice

... showed a significant decline in adult pluripotent bone marrow stem cells ?both potential adverse responses to the vaccinations. Prof Eaton said: "We think the results from the carcinogen-initiated cancers are probably the most important, as they are closer to the 'real-life' model of the development o...

Studies look at how genes affect antipsychotic drug response

... in prolactin (a pituitary hormone that may affect bone development) or weight gain occurs in some but not all of these young patients. "We are trying to determine if some kids are at a greater risk than others for these problems by analyzing genetic markers," Bishop said. Bishop said if children are ...

Hopkins scientists link immune response to 'ghost' parasites and severely congested sinuses

... have debilitating side effects, including loss of bone density, cataracts in the eye and weight gain. An estimated 32 million Americans suffer from persistent inflammation of the tissue that lines the nasal and sinus cavities, according to the United States Centers for Disease Control and Prevention. ...

Study shows antibiotic-resistant bacteria responsible for increase in muscle infections

... infections as well as invasive infections such as bone or joint infections or pneumonia. Failure by physicians to suspect this kind of drug-resistant staph can lead to treatment with the wrong antibiotic. Pyomyositis is an acute bacterial infection of skeletal muscle that produces an abscess within the ...

Natural protein stops deadly human brain cancer in mice

...nt, the researchers relied on a class of proteins, bone morphogenic proteins, that cause neural stem-cell-...irst they pretreated human glioblastoma cells with bone morphogenic protein 4 (BMP4), then injected these treated cells into mouse brains. In mice injected ...

Researchers identify new weapon to fight deadly bacterial sepsis

...IV, using immune-suppressive therapy for organ and bone marrow transplants, and receiving high-dose chemotherapy for cancer. Young children and elderly people are also at a higher risk for the condition because of their weaker immune systems. Now, Assistant Professor Kota V. Ramana and Professor Satish...

Ancient ape ruled out of man's ancestral line

...e sediment encasing Little Foot is harder than the bone ?making extracting him a painstaking process for the South African team. And Drs Latham and Cliff have now turned their own attention to further Australopith findings at Makapansgat, also in South Africa, where other specimens of Australopithecus ...

Drug can quickly mobilize an army of cells to repair injury

... called AMD3100 can mobilize angiogenic cells from bone marrow of human patients in a matter of hours inst...lled G-CSF. Angiogenic cells reside mainly in the bone marrow, and when mobilized they can circulate in the bloodstream, homing to sites of injury and help...

'Best of both worlds' -- Targeting a single gene could inhibit bone decay and stimulate bone growth

...on of a single gene that it is possible to inhibit bone decay while simultaneously stimulating bone formation. This concept may lead to drug treatments for osteoporosis and other bone diseases. Senior...

Artificial cornea offers better results for infants, some blind patients

... years ago, physicians would remove a piece of leg bone from the patient and place the bone over the eye to help it heal and to protect it. And in another procedure still common today, physici...

An advanced genetic diagnostic method for multiple myeloma

...nostic method for multiple myeloma (MM), a type of bone marrow cancer, which permits the detection of this disease in earlier stages. The dissertation of this biologist, produced in the Department of Genetics of the School of Sciences of the University of Navarra, and in the Institute of Human Genetics o...

Muscle and bone from an ink-jet printer

...m mice to differentiate into both muscle cells and bone cells. This is the first report of a system that...c function following heart failure, and heal large bone defects in the skull. Controlling not only what types of cells differentiate from stem cells, but al...

Stem cells found in adult hair follicles may provide alternative to embryonic stem cells

...nteric nervous systems along with endocrine cells, bone and smooth muscle cells. The cells can be isolated...pathies and ALS. Certain defects of the heart, and bone defects (degeneration, craniofacial birth defects) could also be treated through neural crest stem c...

Replacing insulin is top-ranked breakthrough foreseen for health in developing world

...icine has produced a skin substitute (Apligraf), a bone regenerating therapy (Osteocel) and other medical breakthroughs. An eye institute in India (L.V. Prasad) has used adult stem cell therapy to repair the corneas of over 125 blind patients; an estimated 60% of blindness in poor communities is treatabl...

'Trojan Horse' agent halts bone metastasis in mice

...ting agent completely prevented the development of bone tumors in 50 percent of the mice tested in a precl...VEGF121/rGel, stopped specialized cells within the bone from chewing up other bone material to make room for the implanted tumor to grow. Although this s...

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