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Tag: "bone" at biology news

Are scientists making progress in being able to regenerate bone tissue?

...n in restoring the function of diseased or damaged bone by bone tissue regeneration. Until recently, say the authors, the use of bone grafts from a different part ...

Leukemic cells find safe haven in bone marrow

...because molecules released by certain cells in the bone marrow counteract the effect of that drug, accordi...e researchers showed that mesenchymal cells in the bone marrow create a protective niche for leukemic cells by releasing large amounts of asparagine, an ami...

Liposuctioned fat stem cells to repair bodies

... Unlike other sources of adult stem cells, such as bone marrow, fat is abundant and there is no shortage o...related tendon injuries in humans. Therapies using bone marrow stem cells, similar to fat stem cells, have achieved some successes, but the focus is shiftin...

DNA layer reduces risk of reserve parts being rejected

...osphate groups that can speed up the attachment to bone tissue and therefore the integration of bone implants in the native bone tissue. Finally, DNA can be enriched with biologically active factors th...

'Terror bird' arrived in North America before land bridge, study finds

...he rare earth element analysis of a fossil Titanis bone from Texas determines its age to be 5 million year...It is known in the fossil record from a single toe bone in Texas, and in Florida by about 40 bone fragments from different skeletal regions. MacFadden's tea...

Turning a cellular sentinel into a cancer killer

...to reactivate the p53 gene in mice, causing blood, bone and liver tumors to self destruct. The p53 protein is called the "guardian of the genome" because it triggers the suicide of cells with damaged DNA. Inactivation of p53 can set the stage for the development of different types of cancer. The research...

Stem cell therapy shows promise in regenerating damaged muscle in heart attack patients

...esenchymal stem cells (MSC) are found in the adult bone marrow and have the potential to develop into matu...s are derived from normal, healthy adult volunteer bone marrow donors and are not derived from a fetus, embryo or animal. Because they are in an early stage...

Ring-around-the-cell

Breaking down bone is a tough job. Yet, our bones undergo remodeling ...lives, as old material is cleared away so that new bone can form. In diseases such as osteoporosis, an imbalance in this process is responsible for the char...

Scientists identify a candidate gene for osteoporosis

...o osteoporosis—the crippling disease that leads to bone fractures, especially of the hip and spine. The st...nce that a gene called DARC negatively regulates bone density in mice. The report appears online in Genome Research . "If our finding using the mouse mo...

Vitamin D deficiency widespread during pregnancy

... D at birth." A vitamin closely associated with bone health, vitamin D deficiency early in life is associated with rickets ?a disorder characterized by soft bones and thought to have been eradicated in the United States more than 50 years ago ?as well as increased risk for type 1 diabetes, asthma and s...

MIT bioengineer advances survival, promise of adult stem cells

...c cell types. For example, stem cells found in the bone marrow develop into blood cells, bone cells and other connective tissues, and neural stem cells develop into brain tissue. Those stem c...

Research project tackles 'regeneration' gap

...locks of self-renewal that exist within our brain, bone marrow and blood ?with scientists who study how tissues and limbs develop in a variety of organisms. "A salamander can be injured to the point that it loses its limbs or part of its spinal column, yet a few weeks later you’ll see it scurrying acr...

New imaging technique tracks traffic patterns of white blood cells

...rkings of white blood cells in the small veins and bone marrow of mice. "Intravital micropscopy (IVM) has contributed enormously to the recent mechanistic advances in leukocyte trafficking," wrote Mount Sinai School of Medicine researchers lead author Elaine Y. Chiang, Andres Hidalgo, Jungshan Chang and ...

How fish mend a broken heart

... underway, including delivery of growth factors or bone marrow-derived cells that may promote [the formation of new blood vessels]…Success in these pursuits or by directly utilizing epicardial cells or their progenitors could prove favorable for encouraging regeneration from mammalian cardiac progenitor c...

Cloned mice created from fully differentiated cells, a milestone in cloning research

...ages: hematopoietic stem cells, which are found in bone marrow and give rise to all red and white blood cells, and progenitor cells. Granulocytes are well characterized white blood cells unique for their segmented nuclei and the numerous granules in the cells' cytoplasm. Surprisingly, the granulocytes w...

Osteoarthritis may be sign of faster 'biological ageing'

Osteoarthritis, the degenerative inflammatory bone disease, may be a sign of faster "biological ageing," suggests research published ahead of print in the Annals of the Rheumatic Diseases. The authors base their findings on a study of almost 1100 people, aged between 30 and 79. Most of them were fe...

Encouraging results in pancreatic cancer research

...atic cancer, including colon, breast, cervical and bone (osteogenic sarcoma) cancers. These peptides kill cancer cells that do not even contain native p53 protein and therefore appear to have a wide applicability in treating a variety of human cancers. ...

The effects of smoking on fractures and ligament injuries

...tes of hip fracture, fracture healing problems and bone infections and smoking has been shown to impair soft tissue wound healing. Two new studies, funded by the National Institutes of Health and the National Football League Charities, examined the effects of smoking on fractures and ligament healing in m...

German researchers develop first non-invasive test to measure skin aging

...rsus-host disease, which occur when the tissues of bone marrow transplant patients are attacked by immune cells coming from the donor. "Perhaps the technique could help monitor the progress of the disease, or the success of a treatment," Dr. Koehler said. Testing the effectiveness of anti-aging cosmetic p...

New way of tracking muscle damage from radiation

...sues. Ewing sarcoma is a cancer that arises in the bone or soft tissue, usually in the arms, legs, pelvis or chest wall. St. Jude researchers studied the muscles of 13 patients before, during and 12 weeks after they received radiation therapy for soft tissue sarcoma. The team used a technique called q...

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