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Tag: "blueprint" at biology news

Computers to be used to find blueprint for new influenza drug

...,000 grant to use the latest software to produce a blueprint of a designer drug that could stop influenza and s...e sophisticated than previous work. “Developing a blueprint for a new way of fighting influenza is a very important task," said Professor Williams. “We often t...

How an AIDS-Related Cancer Unleashes Inflammation

...e stability of cytokine messenger RNA ?the genetic blueprint for cytokine proteins. The longer these messenger RNAs remain in the cell, the more cytokine proteins the cell's protein-making machinery is able to synthesize, said Ganem. The activation of MK2 also increases production of blood-vessel-forming, or ...

Multiple Campylobacter Genomes Sequenced

...led comparative genomic analysis provides the core blueprint for this important family of human pathogens. And in doing so, it lays the foundation for the development of new ways to monitor and control Campylobacter in the food chain and in human infection. ...

Fleshing out the genome

...ces in living organisms, has leaned heavily on the blueprint metaphor. A large part of the blueprint, unfortunately, has been unintelligible, with no good way to distinguish a bathroom from a boardroom, to link genomic features to cell function. A national consortium of scientists led by BIATECH, a Seattle ba...

Silence the gene, save the cell: RNA interference as promising therapy for ALS

...s faulty and chops it up. As a result, the genetic blueprint isn't delivered and the protein never gets made. "Gene silencing is an example of using "molecular scissors" at its most advanced level," Raoul explains. Raoul and colleagues used RNA interference to reduce levels of mutant SOD1 protein in the spin...

Advancements In Genomics Foster Deep Sea Discoveries

...ity of Padova (Italy), presented the first genetic blueprint for bacterial life in a cold deep-sea environment. They also presented a detailed analysis of how the bacteria’s genetic makeup allows it to function in high-pressure environments. These findings may help lay the groundwork for a variety of research...

High fidelity keeps human DNA assembly line humming

...mplate. DNA is the genetic material that holds the blueprint for life. DNA dictates orders to RNA to make proteins, which give a cell its identity. Mistakes in RNA synthesis can lead to cancer or can support the life cycle of an invading virus. Researchers consider control of RNA synthesis to be a huge issue i...

Moffitt-USF head toward first human trials of anti-cancer drug that targets protein AKT

...trial is that it's molecular therapy, based on the blueprint of the tumor cell." ...

Biologists determine genetic blueprint of social amoeba

...nia, San Diego has determined the complete genetic blueprint of Dictyostelium discoideum, a simple social amoeb...atories. For evolutionary biologists, the genetic blueprint of Dictyostelium, the first amoeba genome to be sequenced, has clarified the place that Dictyosteliu...

Major advance made on DNA structure

...53 the double-helical structure of this biological blueprint for life. One of the fundamental problems in biochemistry is to predict the structure of a molecule from its sequence ?this has been referred to as the "Holy Grail" of protein chemistry. Today, the OSU scientists announced in the Proceedings of the...

Scientists devise way to measure RNA synthesis on the fly in a live cell

...to what extent some RNA molecules help control the blueprint of life. "The standard assumption has been that D...ing for proteins was the sole actor to control the blueprint for all of life," said Philippe Cluzel, an Assistant Professor in Physics at the University of Chica...

UCSD discovery may provide novel method to generate medically useful proteins

...ability arises as DNA is being copied into the RNA blueprint for the protein. The sequence of DNA bases at the 12 sites has unique characteristics that cause frequent mistakes to be made in the copying process. As a result, the RNA ends up specifying a different amino acid, and a protein with different struc...

MicroRNAs have shaped the evolution of the majority of mammalian genes

...senger RNA, or mRNA. Each mRNA molecule contains a blueprint for making a protein. A microRNA can bind to a short sequence on a targeted mRNA and suppress protein production. In a paper published last January in the journal Cell, Bartel's lab, in collaboration with Chris Burge's lab at MIT, presented evidenc...

Study provides insight into cellular defenses against genetic mutation

...eatments for hundreds of genetic disorders. The blueprint for the human body is encoded in genes, many of which hold the information necessary for the building of one or more proteins. Gene expression is the process by which information stored in genes is coverted into proteins that make up the body's struc...

Mouse genome much more complex than expected

...o an enormous encyclopedia containing the complete blueprint of the animal in question. Yet this comparison is ...ike material known as mRNA. Each mRNA contains the blueprint for precisely one specific protein ?this at least has been the traditional doctrine. Three years a...

Role of microRNA identified in thyroid cancer

...olecule of messenger RNA which, in turn, carries a blueprint for the creation of a particular protein. Any mutation in the gene could affect the production of the protein. But recent studies have shown that protein production can also be manipulated indirectly through miRNAs. "MiRNAs can latch on to part of t...

NIH launches comprehensive effort to explore cancer genomics

...tic effort to map the changes in the human genetic blueprint associated with all known forms of cancer," said NIH Director Elias A. Zerhouni, M.D. "This atlas of genomic changes will provide new insights into the biological basis of cancer, which in turn will lead to new tests to detect cancer in its early, mo...

A real time look at interactions between RNA and proteins

...al that programs cells to make proteins from DNA's blueprint and specifies which proteins should be made. There are many types of RNA in the cells of mammals, such as transfer RNA, ribosomal RNA, and messenger RNA–each with a specific purpose in making and manipulating proteins. The workhorses of the cell, RN...

Minimal genome should be twice the size, study shows

...y." Similar methods might also be used to build a blueprint of a bacterium with desired metabolic properties, for example identifying which genes would a bacterium need to efficiently digest specific waste chemicals. The research has been supported by the Hungarian Scientific Research Fund, EMBO, the Human F...

Feinstein researchers identify intelligence gene

...omote their survival. An alteration in the genetic blueprint for dysbindin may ultimately interfere with cell communication and fail to protect brain cells from dying, with a resulting negative impact on cognition and intelligence. ...

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