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Tag: "blood" at biology news

B cells are required for development of epithelial cancer associated with chronic inflammation

...he roles and interactions of these different white blood cells in the progression of cancer. The mice used...stem resulted in a failure to recruit innate white blood cells to premalignant skin and an absence of chronic inflammation. As a consequence, parameters of e...

Researchers pioneer new gene therapy technique using natural repair process

...ease." Sickle cell disease is a disorder in which blood cells carry a mutation in hemoglobin. The mutation causes the blood cells to change shape, preventing them from flowing through the blood vessels efficiently. One out o...

Newer imaging techniques may lead to over-treatment

...e arteries in the lungs, including detecting small blood clots not previously seen, but seeing more may have little impact on the patient's outcome, a new study suggests. The study included 198 patients with suspected pulmonary embolism. About half of the patients (98) had a multidetector CT (MDCT) examin...

15 generations of untrained jocks, couch potatoes show big physiological adaptations

...(proportionally larger hearts (16% ) and increased blood flow (33%), reported in Kirkton et al., below) and respiratory systems (proportionally larger lungs (17%) and better oxygen diffusing capacity, reported in Giuliano et al., below) over the G7 stage, the researchers pointed out. Oxygen delivery syste...

New miniaturised chip dramatically reduces time taken for DNA analysis

...ared food; identifying people, either to establish blood relations or to find criminal evidence; and testing the toxicity of different drugs to establish what damage they may cause to the DNA molecule of disease-causing microorganisms and of cells in patients. "The next step is to mass-produce the sensors...

Chronic Sinus Infection Thought To Be Tissue Issue, Mayo Clinic Scientists Show It's Snot

... chronic sinus infection patients, activated white blood cells (eosinophils) cluster in the nasal and sinus mucus and scatter a toxic protein (major basic protein) onto the nasal and sinus membrane. While major basic protein was not distributed in the nasal and sinus tissue, the level of this protein in th...

NCI Researchers Confirm the Effectiveness of Immunotherapy Approach to Treating Melanoma

...ated lymphocytes. Autologous lymphocytes are white blood cells that have been removed from the patient, act...he patients, and then lymphocytes, a type of white blood cell in the blood that can attack tumors, were separated from other parts of the blood. Next, patien...

Antiretroviral Therapy May Prevent HIV Transmission From Breastfeeding Mothers To Infants

...gs, nevirapine, lamivudine, and zidovudine, in the blood and breast milk of 20 HIV-infected women, and in the blood of their uninfected breastfeeding infants. All of the mothers had been receiving this combination of...

UCLA cancer researchers shake loose hidden biomarker

...ation in a cell ?where it could not be accessed by blood ?to another, easier to target area. The discovery...d in the apical region of the cell membrane, which blood can't reach, so injection of immunotherapy into the bloodstream is not effective," said Rajasekaran,...

Brain Scan Study of Smokers Reveals Signature of Craving

...d radio waves are used to produce images depicting blood flow in brain regions. That blood flow reflects brain activity in those regions. As a group, smokers' brain responses to drug cues re...

Discovery could be key to bioterrorism defense

...central nervous system, as well as in cells lining blood vessels. It is essential for central nervous system development and blood vessel growth in the embryos of humans and other mammals. Broder and his team are among only a hand...

Team Invents Device For Weighing Individual Molecules

... reasons because 95 percent of the proteins in the blood have nothing to do with cancer." The new method might ultimately permit the creation of microchips, each possessing arrays of miniature mass spectrometers, which are devices for identifying molecules based on their weight. Today, high-throughput pro...

How exactly does the brain control breathing?

...tral chemoreceptors are found close to the midline blood vessels of the brainstem allowing them to 'taste' the pH of the blood. His cells do not contain glutamate but a substance called serotonin. Experimental Physiology asked each author to stake out his claim and provide rebuttals and critiques of each ...

Malaria mechanism revealed

...otein that enables malaria parasites to invade red blood cells, researchers have uncovered valuable clues f...erozoite-stage parasites ("merozoites") invade red blood cells, leading to clinical symptoms and in many cases, death. "Niraj Tolia [the first author of the...

Immune system's distress signal tells bacteria when to strike back

...owel wall, bore its way through, and flow into the blood stream. As a consequence, patients with widespread Pseudomonas infection often die within a few days. Alverdy and colleagues were able to pinpoint key early steps of this lethal process. The transformation starts when a weakened host tries to boost ...

Random gene expression may drive HIV into hiding

...IV normally replicates rapidly in the body's white blood cells, but, in some cells, the virus stops replicating and becomes dormant. Researchers have long puzzled over how HIV makes the "decision" to become latent or to keep replicating in a certain cell. "Most of the other groups studying the molecular m...

MIT engineers an anti-cancer smart bomb

...nti-angiogenesis," the theory that cutting off the blood supply can starve tumors to death. That strategy c...umor cells of oxygen, prompting them to create new blood vessels and instigate metastasis and other self-survival activities. The next obvious solution woul...

Stem cells in bone marrow replenish mouse ovaries

...recognized stem cells found in the bone marrow and blood of mice can "restock" a depleted ovary with new eg...arkably, the researchers found that bone marrow or blood cell transplants appear to completely revive the ovaries of female mice sterilized by chemotherapy. ...

Circulating stem cells play small role in lung repair

...w, where some remain while others circulate in the blood stream. Their main function is to produce all of t...eoli ?tiny hollow sacs along the airways where the blood takes in oxygen and discards carbon dioxide. The processes by which alveoli recover from damage are...

Excess liver gene protects against high-fat diet

...n fat, remained free from the high cholesterol and blood vessel plaques exhibited by animals with the norma...rmal, balanced diet, the excess receptors worsened blood lipid levels, the researchers reported. The findings suggest that natural variation among individua...

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