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Tag: "blocker" at biology news

Discovery of an HIV inhibitor in human blood points to new drug class

... infecting immune cells and multiplying. The virus blocker might play a role in the progression of HIV to full-blown AIDS and—because it works in a different way than existing antiretroviral inhibitors—could lead to the development of another class of drugs in the fight against the pandemic disease, research...

Anti-fungal drug stops blood vessel growth

... least, that itraconazole popped up as a potential blocker of angiogenesis,?says Jun O. Liu, Ph.D., professor of pharmacology. “We couldn’t have predicted that an antifungal drug would have such a role.? In their search for antiangiogenesis drugs, the researchers worked with cells from human umbilical cord...

Blocking the nerve receptor EP1 in mouse models reduces brain damage caused by stroke

...ects." Doré's team first injected either the EP1 blocker ONO-8713 or the EP1 stimulator, ONO-DI-004 into th...olume of damage in mice treated first with the EP1 blocker ONO-8713 was only about 71 percent that of controls. "ONO-8713 significantly reduced brain damage ...

New type of rejection blocker protects kidneys after transplant

...s who took the experimental drug, a co-stimulatory blocker called belatacept (LEA29Y), also had better kidney function and experienced less of the toxic side effects associated with standard anti-rejection drugs, including kidney damage, high blood pressure and high cholesterol. In the August 25 issue of Th...

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