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Tag: "biopsies" at biology news

Gene expression test reveals ER and HER-2 status of breast tumors

.... The samples included both fine needle aspiration biopsies and traditional biopsies. The team used 195 fine-needle biopsy samples to set gene expression thresholds that predicted ER-positive status with 90 percent accuracy and HER-2-positive status with 93 percent accuracy. They then applied those thresho...

Intravenous nanoparticle gene therapy shows activity in stage IV lung cancer

...linded analysis of pretreatment and post-treatment biopsies of three patients' tumors show that expression of FUS1 was absent from pretreatment samples while a high level of FUS1 was expressed in tumors after treatment. FUS1 can induce apoptosis - programmed cell death - in cancer cells but is frequently ...

Ultrasound upgrade produces images that work like 3-D movies

...rasound-guided medical procedures, including tumor biopsies and robot-assisted surgeries done through tiny "ke...mals of a heart valve and blood vessels and needle biopsies of the animals' brains and esophagi. The researchers have since recorded ultrasound images of a m...

Why don't all moles progress to melanoma?

... ?involving melanocytes from normal human skin and biopsies of non-malignant human moles ?are being published in the October issue of Nature Cell Biology. The endoplasmic reticulum is the cell's protein production factory. The process begins when chains of amino acids are deposited in the ER membrane in res...

Early HIV treatment fails to restore memory T cells

...ory cells return as well. By performing intestinal biopsies on volunteers who started HIV treatment shortly after infection, the researchers found that, unlike in blood, intestinal T cells remained low even after several years of HIV treatment in 70% of volunteers, even though only a tiny fraction of these ce...

Elasticity imaging identifies cancers and reduces breast biopsies

...ue could significantly reduce the number of breast biopsies required.? The American Cancer Society (ACS) est... characterized as malignant. Ultrasound-guided biopsies were performed on 80 patients with 123 lesions. Biopsy showed that elasticity imaging correctly iden...

Mayo Clinic Cancer Center: Harnessing the measles virus to attack cancer

... a clinically-available assay. Repeat brain tumor biopsies for this purpose are not always safe or ethically justified. Instead we can monitor viral propagation in the tumor with a blood test, allowing us to adjust the dosage to increase the likelihood of therapeutic benefit." Eligible candidates for the...

Vaccine shown effective against chancroid

...e it needs to survive, the authors said. In skin biopsies of the immunized animals, the researchers found no viable chancroid bacteria. An HIV vaccine has been elusive in part because the virus constantly varies its surface molecules, making it an ever-changing target. But H. ducreyi, unlike other sexually...

Polymers show promise for lab-on-a-chip technology

...be used, for example, to analyze blood samples and biopsies much faster, cheaper and more comprehensively than current methods. In the past, most microscale research and development funds have targeted silicon, the fundamental material in the semiconductor industry. But LCPs are less brittle and more pliable...

UC Davis study finds HIV hiding from drugs in gut, preventing immune recovery

...tiretroviral therapy should be monitored using gut biopsies and that the gut's immune function be restored thr...ammation, starting treatment earlier and using gut biopsies to monitor treatment success. "If we are able to restore the gut's immune response, the patient w...

Predicting successful outcomes in living-donor liver transplants

...ds of measuring liver function, specifically liver biopsies that were performed in 17 of the patients and liver scintigraphy (an imaging technique using a radioactive substance that is swallowed) performed on 18 patients. The ICG test however, had certain benefits. "This novel noninvasive method has advantage...

Inflammation and drugs to control this activity studied in a variety of tumors sites

...k of developing prostate cancer. Results of repeat biopsies of prostate tissue over a five-year period from me...co-workers examined the results of prostate needle biopsies from 177 men between ages 47 and 83 years who were at high risk for developing cancer based on eithe...

Growth factor-promoting angiogenesis expressed in tumor cells and normal neurons

...that standard invasive procedures such as surgical biopsies or partial tumor resections may be inducing a proangiogenic response, or trigger, within the brain," cautions Dr. Fine. ...

Researchers create pigs that produce heart-healthy omega-3 fatty acids

...s tumor data from 268 patients, including multiple biopsies within each tumor. On average, these patients were followed for 4.4 years, during which time 37 developed cancerous tumors. Overall, the database used in the study represents more than 32,000 distinct genotypes of different cells within the tumors. ...

Evolutionary biology research techniques predict cancer

...s tumor data from 268 patients, including multiple biopsies within each tumor. On average, these patients were followed for 4.4 years, during which time 37 developed cancerous tumors. Overall, the database used in the study represents more than 32,000 distinct genotypes of different cells within the tumors. ...

Living taste cells produced outside the body

...r, Rawson, and colleagues intend to use taste cell biopsies from humans to try to grow human taste cells. ...

Carnegie Mellon develops non-invasive technique to detect transplant rejection at cellular level

...ng a heart transplant by performing frequent heart biopsies for the first year. Heart biopsies are invasive procedures that involve threading a catheter through the jugular vein to the heart's ri...

Jefferson biologist coaxing human embryonic stem cells to make dopamine with simpler, faster method

...une response relies on invasive procedures such as biopsies to gather tissue that can be analyzed to determine how well or how poorly the body is faring against disease. The advantage of using the new PET technique, said Witte, is that surgical procedures are avoided and a PET scan can give clinicians a pictu...

PET imaging reveals the immune system at work

...une response relies on invasive procedures such as biopsies to gather tissue that can be analyzed to determine how well or how poorly the body is faring against disease. The advantage of using the new PET technique, said Witte, is that surgical procedures are avoided and a PET scan can give clinicians a pictu...

Anti-cancer drugs may hold promise for premature aging disorder

...when they used FTIs to treat cells grown from skin biopsies of progeria patients: Cell blebbing decreased to near normal levels. In addition to Capell and his colleagues in NHGRI's Genome Technology Branch, researchers from the University of North Carolina at Chapel Hill and the University of Michigan School...

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