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Tag: "biomolecules" at biology news

By creating molecular bridge, scientists change function of a protein

...hod may provide "a general approach to engineering biomolecules and biosystems such as receptors, enzymes, antibodies, ribosymes, DNAzymes and viruses with novel functions." Zhao is a member of the Institute for Genomic Biology and the Center for Biophysics and Computational Biology at Illinois. He also is an af...

Motor transport in bio-nano systems

...may witness the development of sorting devices for biomolecules and biocolloids, drug delivery systems that utilize the motor transport within human cells, and motile components for nanoscale manufacturing. Long term, we should also be able to construct 'smart' biomimetic systems which are able to respond to and ...

Researchers Create DNA-Based Sensors for Nano-Tongues and Nano-Noses

... DNA is what makes these sensors so capable. These biomolecules can be engineered, in a process called directed evolution, to recognize a wide variety of targets, including small molecules and specific proteins. Likewise, the nanotubes are ideal for signalling when the DNA has captured a target molecule. Single-...

Drugs from the deep blue

...up works with calcium channel modulators and other biomolecules derived from plants and scorpion venom. But when Pessah and Molinski got to talking at a party some years ago, they quickly realized that they could apply the same methods to screen 124 sponges that Molinski's group had recently collected off the coa...

Biotechnology's newest chemical tool

...this technique is likely to be applicable to those biomolecules as well, further expanding its utility. Klimasauskas said that one potential application might be to label various sites in the ribosome -- the RNA-based site of protein production -- with bright fluorophores using appropriate RNA methyltransferases,...

How plants avoid feeling the burn

...to ward off the sun's harmful rays. "We knew that biomolecules called carotenoids participate in this process of photoprotection, but the question has been, how does this work?" said Iris Visoly-Fisher, a postdoctoral research associate in the Biodesign Institute at Arizona State University. Carotenoids act a...

'Micro-boxes' of water used to study single molecules

...e boxes by briefly shaking a mixture of water, the biomolecules to be studied, and a fluorocarbon medium. Water dr...face that might interfere, can readily encapsulate biomolecules (which prefer being in water as opposed to the fluorocarbon medium), and can readily fuse together t...

Researchers uncover new mechanism of tumor suppressor

...ing and regulation by chromatin- and lipid-binding biomolecules implicated in cancer and other human diseases. She employs high field Nuclear Magnetic Resonance spectroscopy, X-ray crystallography and other biochemical and biophysical approaches to elucidate three-dimensional atomic-resolution structures and dyna...

Free radical cell death switch identified

...ules that inflict cellular damage by reacting with biomolecules including DNA, proteins, and lipids. A lifetime of oxidative stress leads to general cellular deterioration associated with aging and degenerative diseases. How the oxidative-stress signals trigger these profound effects in cells has remained unclea...

Researchers make nanosheets that mimic protein formation

...ilding principle for producing organized arrays of biomolecules with controlled geometrical and physicochemical surface properties," Glotzer said. "In the fabrication of functional nanoscale materials and devices, self-assembly offers substantial advantages over traditional manufacturing approaches, if we can des...

Electric jolt triggers release of biomolecules, nanoparticles

...way to use a brief burst of electricity to release biomolecules and nanoparticles from a tiny gold launch pad. The technique could someday be used to dispense small amounts of medicine on command from a chip implanted in the body. The method also may be useful in chemical reactions that require the controlled rel...

Scientists win grants to develop $1,000 genome sequencing technology

...rt on using electric fields to actively manipulate biomolecules and assemblies of nanostructures. His expertise will be utilized to accelerate and enhance the sequencing process. The UCSD team will use an experimental method for DNA sequencing aimed at developing a method for fabricating high-density arrays of...

Gene-bender proteins may sway to DNA

...ile stopped-flow technique can capture dynamics of biomolecules occurring on millisecond time-scales or longer, the goal of this study was to extend the time-resolution down to sub-microseconds. It gave us a new time window on probing protein-DNA interactions," Ansari said. That broader time window, obtained in...

Selecting life: Scientists find new way to search for origin of life

...ut which of the countless possible combinations of biomolecules and mineral surfaces were key to this evolution? T...therefore, is how just the right blend of critical biomolecules was selected, concentrated, and organized from the diverse primordial "soup." Previous research by t...

Gold nanoparticles prove to be hot stuff

...h apply force to and track the position of fragile biomolecules such as DNA or protein by manipulating a tiny sphere--typically polystyrene--attached to the molecule. The JILA team would like to find new microsphere materials that can be trapped by laser radiation pressure more efficiently, which would enable fas...

FSU researchers determine a critical factor in workings of proteins

...rmally, fast association of the protein with other biomolecules is critical for the creation of proper cell structures. The failure of the protein to associate quickly, then, is the root cause of the condition." In their Structure paper, Zhou and graduate student Razmi Alsallaq put forth a new theory that has ...

Magnetic computer sensors may help study biomolecules

...capturing and sorting, large numbers of individual biomolecules simultaneously for massively parallel medical and ..., combined with computer modeling, suggest that if biomolecules such as proteins or DNA strands were attached to the magnetic particles, the spin-valve array could ...

In nature, proteins sweep up nanoparticles

...Planetary Sciences. “The intriguing discovery that biomolecules may shape nanoparticles into larger aggregates, which reduces the nanoparticles’ mobility, could have significant implications for bioremediation.” Moreau conducted the research under the guidance of Jill Banfield, a principal investigator in the ...

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