Scripps research study reveals structural dynamics of single prion molecules
...s could prove important in understanding the basic biology of amyloid formation, as well as in designing strategies against misfolding diseases." Interestingly, the new study revealed that yeast prion protein Sup35 lacks a specific, static structure in its native collapsed state. Instead, the compact prot...New molecular pathway could reveal how cells stick together
...urfaces. Andrea Page-McCaw, assistant professor of biology at Rensselaer and principal investigator for the project, has focused on matrix metalloproteinases (MMPs) -- proteins that play a role in development and immunity. "MMPs have gotten a lot of attention primarily because of their regulation in a lo...Is there a pilot in the insect?
...tood more exactly by permanently shuttling between biology and robotics. These principles have been tried and tested for millions of years, and today they need to be applied to aerospace, because the phases in which an airship or a space module navigates close to the ground are absolutely crucial. The res...World's largest flower evolved from family of much tinier blooms
...assistant professor of organismic and evolutionary biology in Harvard's Faculty of Arts and Sciences. "As a parasite living inside the tissue of a tropical vine, the plant lacks leaves, shoots, or roots, making it difficult to compare to more conventional plants. Most efforts to place plants in the botanical...New study may show how to forestall a fatal, virus-caused immune-system meltdown
...thology Judith Aronson, biochemistry and molecular biology instructor Heidi Spratt, and biochemistry and molecular biology professors David Gorenstein and Bruce Luxon. Funding for the investigation was provided by the Defen...Researchers urge monitoring of bone health during chemotherapy
... M.D., assistant professor of medicine and of cell biology and physiology. "But there are things that can be done to counteract this. Physicians should carefully monitor their cancer patient's bone health with regular bone density scans (DEXA) and prescribe medications to prevent bone loss when needed. And p...Exploring the molecular origin of blood clot flexibility
... its stretchiness may have broader implications in biology and medicine. By understanding mechanical processes at the molecular level, it may eventually be possible to see how they relate to the mechanical properties of single fibers and a whole clot. This knowledge may enable researchers to make predicti...Scientists find new genetic clue to cause of Alzheimer's disease
...hat the group was "encouraged and excited" by cell biology experiments that demonstrate SORL1's role in production of beta amyloid fragments. Examining blood cells from people with and without Alzheimer's, the researchers found less than half the level of SORL1 protein in people with Alzheimer's compared ...HIV protein enlisted to help kill cancer cells
...e and surgery and associate professor of molecular biology and pharmacology. Hotchkiss was seeking proteins that inhibit apoptosis in patients with life-threatening infections and found that TAT-Bim had the unwanted effect of increasing cell death. Hawkins wondered if TAT-Bim could be effective against cance...Application of Genomatix in silico methods reveals novel cancer associated genes
Genomatix Software GmbH, an in silico systems biology company with headquarter in Munich (Germany), rele...e introduced our own concepts of an annotation and biology driven microarray analysis pipeline, and were heavily contested in the beginning. Today it is so rew...UF scientists discover new genus of frogmouth bird in Solomon Islands
...iquated or casual observations," Remsen said. "The biology of birds in these regions is, to a great extent, obscured by stale, hand-me-down classifications from an earlier era. A combination of detailed morphological and genetic analyses reveal that this frogmouth ?formerly dismissed as just a race of an exi...Cancer researchers add spice to research against rare neuromuscular disease
...r clog in neurons affected by Kennedy disease. The biology of the disease is bit like Huntington's disease, a more common neurodegenerative disease that is inherited, fatal, and unyielding in its progression. Both are caused by an abnormal repeat of three nucleotides, CAG, though not in the same gene ?a kind...Jefferson researchers' discovery may change thinking on how viruses invade the brain
... assistant professor of biochemistry and molecular biology at Jefferson Medical College. "We found that while transport must happen ?it’s essential to viral infection and spread and disease progression ?it’s not through this mechanism. There’s more to the story." "We think we have to have a closer look at...Gene chips forecast ecological impacts of climate change
Gretchen Hofmann, an associate professor of biology at the University of California, Santa Barbara, wi... a talk about the use of technologies in molecular biology to assess climate-change related impacts on marine invertebrates at the annual meeting of the Americ...Biologists produce global map of plant biodiversity
...ir richness," says Jetz, an assistant professor of biology at UCSD and the senior author of the paper. "Tropical countries such as Ecuador or Colombia harbor by a factor 10 to 100 higher plant species richness than most parts of the United States or Europe. The question is, Why?" While explorers to these ...Mosquito genes explain response to climate change
...ina M. Holzapfel, researchers in the department of biology and members of the UO Center for Ecology and Evolutionary Biology. "For the first time, we are moving down the track to identify genes that animals use to control their seasonal development," Bradshaw said. "Response to day length is often the pri...Primitive yeast yields secrets of human cholesterol and drug metabolism
...ter Espenshade, Ph.D., assistant professor of cell biology at Johns Hopkins. “We’re excited because although we originally identified this protein in yeast, humans not only have the same protein, but it works the same way.? The search for Dap1 began with the hunt for factors that influence the actions of a......hoi, associate professor of molecular and cellular biology at BCM and his colleagues. When flies completely lack the protein, they do not live very long. However, when flies have only a little TCTP in their cells, they are very small, said Choi. Graduate student Ya-Chieh Hsu, through a series of studies...Making mice with enhanced color vision
...Jeremy Nathans M.D., Ph.D., professor of molecular biology and genetics, neuroscience, and ophthalmology at Hopkins. "The answer is, remarkably, yes. They did not require additional generations to evolve new sight." Retinas of primates such as humans and monkeys are unique among mammals in that they have ......20 years ago, researchers in the laboratory of MIT biology professor Anthony Sinskey started swapping genes between different bacteria, hoping to achieve industrial production of desirable natural compounds synthesized by those bacteria. The researchers focused their "biopolymer engineering" efforts on a ...