15-year hunt finds cause of pseudothalidomide syndrome
..., Canada and Italy and to provide insight into its biological effect. "For decades now, we've known that the appearance and number of chromosomes were abnormal in people with Roberts syndrome, but we hadn't been able to figure out why or how," says Ethylin Jabs, M.D., a professor in the McKusick-Nathans Instit...Comprehensive biodefense text published
...nd development of diagnostic tests for identifying biological warfare pathogens. Intended for researchers, physicians, and policy makers, Biological Weapons Defense: Infectious Disease and Counterbioterrorism offers a detailed look at the ongoing efforts to detect and identify these disease-causing agents, incl...TrueBlue Archive Will Store Raw Life Sciences Data for Proteomics and Drug Testing
...nd development of diagnostic tests for identifying biological warfare pathogens. Intended for researchers, physicians, and policy makers, Biological Weapons Defense: Infectious Disease and Counterbioterrorism offers a detailed look at the ongoing efforts to detect and identify these disease-causing agents, incl...Gov't Creates Gene Database of Normal Human Tissues
.... Scientists can compare the genes from their own biological samples to this dictionary of normal expression. "... profiles from different organs that share similar biological functions also showed patterns of expression. For example, though the cerebrum and the cerebellum ar...Building a protein name dictionary from full text: a machine learning term extraction approach
The majority of information in the biological literature resides in full text articles, instead ...ture mining tools rely on pre-existing lexicons of biological names, often extracted from curated gene or protein databases. This is a limitation, because such da...Ancient immune defense mechanism is no match for HIV-1
...Tat is an SRS also helps explain the long-standing biological observation that when HIV-1 is engineered to be lacking Tat but contains alternative transcriptional activators, it fails to spread productively in human cells." The researchers also suggest that their findings raise a challenge to proposed therapeut...NHGRI targets 12 more organisms for genome sequencing
...of a diverse set of organisms is to understand the biological processes at work in human health and illness," sa...s, the use of parasitoid wasps in agriculture as a biological control of crop damaging insects saves approximately $20 billion annually. The wasp will serve as a ...Purdue researchers use enzyme to clip 'DNA wires'
...ers created with "molecular electronics," in which biological molecules might be harnesses to create devices for computers, sensors and other uses. Self-assembly might be used in the future to create electronic devices at lower cost than is possible with conventional manufacturing processes. Purdue researchers...Analysis Of Human Genome To Predict The Development Of Illnesses
...heir molecular function, molecular composition and biological process. With the unknown ones, they are logged (comparing similarities and differences with respect to these same molecules in other living things) and molecules with a similar sequence to theirs are observed in order to deduce their function and to...Nanobacteria in clouds could spread disease, scientists claim
... of the authors, must overwhelm all other types of biological particles in the atmosphere. ...A hope for oil spill bioremediation
...taminated coastal marine water samples. Due to its biological origin, crude oil is very depleted in 13C. Therefore, its biodegradation product CO2 will also be more 13C depleted as compared with the typical marine DIC and atmospheric dissolved CO2. The sampling area is an energetic system poor in organic mater...Chemical Engineer Kao Explores Antibiotic Synthesis With DNA Chips
...echnique has tremendous potential for the study of biological processes where numerous genes work in concert--an apt description of antibiotic synthesis. A microarray consists of single-stranded DNA arranged on a wafer the size of a postage stamp. The genetic sequence of the DNA tethered to the chip is known. ...Scientists identify genes responsible for 'black rot' disease in vegetables
...iously described Xcc genomic sequence. To test the biological implications of this observation, they inoculated five different vegetable species with the three mutants corresponding to these strain-specific genes, and they observed significant differences in the response of each host species to infection. The a...Engineers improve plastic's potential for use in implants by linking it to biological material
...e nerve regeneration, blood vessel growth or other biological processes. In the study led by Dr. Christine Schm...ed for a stable attachment between polypyrrole and biological molecules that T59 would be used to link to. Schmidt's laboratory intends to study T59 as a linker ...Ebola virus: from wildlife to dogs
...tners (1) have been working to unravel the virus's biological cycle, in other words the whole range of ways in which the virus circulates in its natural environment, from its natural host (or reservoir) right up to humans. They showed that strong epidemics of Ebola have decimated populations of large primates o...Bugs, even 'bad' ones, can be educationally beneficial, new book says
...ok is written for a general audience. "Many basic biological concepts such as evolution and genetics can be learned through pests," Waldbauer said. For example, he described recent evidence of how a new species of fruit fly is evolving based on how its diet differentiates it from other fruit flies. Waldbauer ...Innovative coating could give medical implants a longer life
...nelise Barron, associate professor of chemical and biological engineering and an author on the paper. Barron is an expert at creating peptoids -- synthetic molecules that are closely related to the natural proteins or peptides they mimic but don't degrade in the body. Messersmith and Barron wanted to use this ...Newly discovered protein an important tool for sleeping sickness research
...provide the scientists a new tool to elucidate the biological function of this unique modified DNA base in the regulation of antigenic variation. If base J does indeed play a role in the gene silencing that enables the trypanosome to change its antigen coating, the discovery of JBP2 may one day enable scientis...Breakthrough System for Understanding Ocean Plant Life Announced
...provide the scientists a new tool to elucidate the biological function of this unique modified DNA base in the regulation of antigenic variation. If base J does indeed play a role in the gene silencing that enables the trypanosome to change its antigen coating, the discovery of JBP2 may one day enable scientis...NYU, Rockefeller researchers find complexity of regulation by microRNA genes
...nslation. However, little has been known about the biological function of microRNAs--a process the current study sought to explore. The paper, published in the latest issue of the journal Nature Genetics, found that a microRNA gene regulates, on average, 200 different human gene transcripts and that many micro...