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Tag: "bioinformatics" at biology news

Yale Scientists Find MicroRNA Regulates Ras Cancer Gene

...-7 as a cell division regulator, Slack's team used bioinformatics and found the relationship to Ras. Let-7 in humans is identical to the sequence in the worm, and both binding site and pathway for Ras are highly conserved. Tissue from lung cancer tumors, compared with their normal adjacent tissue, had reduced let-...

Scientists reveal molecular secrets of the malaria parasite

...on this project while in his previous positionas a bioinformatics scientist at Sanger. He was also the first authorof the 2002 study —led by scientists at TIGR, Sanger, and StanfordUniversity —that presented the complete genome of Plasmodiumfalciparum, the deadliest human malarial parasite.Hall says the Science pap...

Agilent Technologies releases automated literature search tool for biology researchers

...as a free plug-in to Cytoscape 2.1, an open-source bioinformatics platform that enables researchers to form a visual...rch_screens.html. About Cytoscape Cytoscape is a bioinformatics software platform for visualizing molecular interaction networks and integrating these interactions ...

Nonlinear Dynamics announces more details of its global partnership with PerkinElmer

Nonlinear Dynamics Ltd, a leading provider of bioinformatics solutions, today announced further details of its ... establish a single strong proteomics software and bioinformatics partner going into 2005 and beyond. In entering this collaboration with Nonlinear, we are firmly end...

Study: 'homemade' gene expression technology unreliable

... biology, OHSU School of Medicine, led the initial bioinformatics research that supported the Nature Methods publication. "The gene chip is a revolution in technology that is hoped rapidly to advance understanding of biological mechanisms and methods to assess the actions and effects of drugs and chemicals," said ...

Agilent Technologies releases probe sequence, annotation information for all its commercial gene expression microarrays

...quences will be of great benefit to the microarray bioinformatics community and to databases such as the NCT's CEBS as we seek to make high-quality toxicogenomics data sets publicly available." The microarray design and probe sequence information is now available on Agilent's eArray web portal at earray.chem.agile...

Virus-host interactions at sea effect global photosynthesis

...quences will be of great benefit to the microarray bioinformatics community and to databases such as the NCT's CEBS as we seek to make high-quality toxicogenomics data sets publicly available." The microarray design and probe sequence information is now available on Agilent's eArray web portal at earray.chem.agile...

B-15A collides with Antarctic ice tongue

...quences will be of great benefit to the microarray bioinformatics community and to databases such as the NCT's CEBS as we seek to make high-quality toxicogenomics data sets publicly available." The microarray design and probe sequence information is now available on Agilent's eArray web portal at earray.chem.agile...

wFleaBase: the Daphnia genome database

...neric Model Organism Database project, and related bioinformatics tools. Over the coming year, preliminary genetic maps and the nearly complete genomic sequence of Daphnia pulex will be integrated into wFleaBase, including gene predictions and ortholog assignments based on sequence similarities with eukaryote gene...

Software Tool for Converting Scientific Text into a Database of Functional Relationships

...selected sources, and integrate MedScan with other bioinformatics tools for further analysis of extracted information. For more information about MedScan, or for a web-based trial, visit Ariadne Genomics website www.ariadnegenomics.com/products/medscan About Ariadne Genomics Ariadne Genomics is a Maryland-based c...

Analysis Of Human Genome To Predict The Development Of Illnesses

...ts such as cancer, depression and hepatitis. This bioinformatics tool, designed in collaboration with the Centre for Applied Research in Medicine (CIMA) at Navarre University and known as GARBAN (Genomic Analysis for Rapid Biological Annotation), carries out the following process: firstly, it hierarchically classi...

NYU, Rockefeller researchers find complexity of regulation by microRNA genes

...ematical Sciences. Rajewsky's research program on bioinformatics predictions of regulatory elements in genomes is being conducted at NYU's Center for Comparative Functional Genomics, where the focus of the research programs is to combine genomic approaches with developmental genetics and evolution to understand ho...

Lipids get new comprehensive classification system

...hat occur with cellular metabolism, and to develop bioinformatics approaches that establish dynamic lipid networks. In order to coordinate their efforts with those of other groups, such as the Lipid Bank in Japan, the European Lipidomics Initiative, and the International Conference on the Biochemistry of Lipids bas...

Understanding how bacteria communicate may help scientists prevent disease

...llaborators at Princeton solved the mystery. Using bioinformatics and modeling, Kulkarni drafted theoretical predictions for the missing regulatory element, which were confirmed experimentally by his colleagues at Princeton. "We showed that the crucial missing element was a group of genes called small RNAs. ("The ...

Open Access journals get impressive impact factors

... Launched in 2000, it is the second highest ranked bioinformatics journal, and already has an impact factor comparable to that of Bioinformatics (5.74), the most established journal in the field, which has been publishing for more than two decades and is supported by a major society. BMC Genomics enters the Journa...

Program finds lost genes in nematode genome

...Michael Brent Michael Brent Brent has brought his bioinformatics skills to many genomes, including those of mammals, other nematode species and most recently the fungus Cryptococcus neoformans. Brent's approach to gene prediction stands traditional genome annotation on its head because it starts with a computer an...

'Bionic' arm gives amputee sense of touch

... Launched in 2000, it is the second highest ranked bioinformatics journal, and already has an impact factor comparable to that of Bioinformatics (5.74), the most established journal in the field, which has been publishing for more than two decades and is supported by a major society. BMC Genomics enters the Journa...

Bioinformatics reveals new gene regulation system

...ery detailed description of a system just by doing bioinformatics alone," says Gelfand, director of the IITP's resea...hat binds to the NrdR-box. To do this, they used a bioinformatics approach they call phylogenetic profiling, compiling a list of genomes that clearly contained the Nr...

Drawing with DNA: 'Bioart' illuminates genomics

...gram in the human dataset, it triggers a real-time bioinformatics comparison: BLAST begins to run, searching through the rice data for a homologue ?conducting in a novel (and visible) way the same sequence analysis done by scientists. Results are presented as two superimposed pictograms. "This high-dimensional vis...

New bioinformatics technique for systematically analyzing key regions in DNA that help control gene activity

... Uppsala University in Sweden have developed a new bioinformatics technique for systematically analyzing key regions in DNA that help control gene activity. The cooperative efforts were headed by Krzysztof Fidelis in the United States and by Jan Komorowski in Sweden. Understanding the complex regulatory mechanisms...

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