Cellular scale drug delivery from the inside out
...e focus of Lin's work. The caps can be dendrimers, biodegradable polymers, genes, proteins, metallic nanoparticles, or semiconductor nanocrystals ?also known as quantum dots ?and are held in place by chemical bonds. Once the nanospheres are inside the target cells, a trigger is used to pop the caps off and release...Researchers use 'trickery' to create immune response against melanoma
...trolled drug release made from a biocompatible and biodegradable PLA polymer system and encapsulated a fluorescently labeled model drug within them, in order to visualise nanoparticle uptake into target cells. The nanoparticles in question were designed for attachment to aptamers so that the binding properties of ...Targeted drug delivery achieved with nanoparticle-aptamer bioconjugates
...trolled drug release made from a biocompatible and biodegradable PLA polymer system and encapsulated a fluorescently labeled model drug within them, in order to visualise nanoparticle uptake into target cells. The nanoparticles in question were designed for attachment to aptamers so that the binding properties of ...Cells from amniotic fluid used to tissue-engineer a new trachea
...enchymal cells in culture, then "seeded" them onto biodegradable tubes of the needed dimensions and shape. The tubes and cells were then exposed to growth factors that caused the mesenchymal cells to differentiate into cartilage cells. When the engineered grafts were ready, they were used to reconstruct defective ...A hope for oil spill bioremediation
...n. It is well established that most crude oils are biodegradable to a great extent, especially components as short linear alkanes or simple aromatic hydrocarbons. However, the heavy fraction, made of long-chain saturated and polyaromatic hydrocarbons and a considerable fraction of asphaltenes and resins, is genera......san nanoparticles -- minisculenaturally-occurring, biodegradable particles that stick tomucous-producing cells lining the lungs. The RNA produced isspecifically designed to suppress the protein NS1. Without NS1, thehost antiviral defense remains intact and the virus cannot reproduce.Mice treated intranasally with ...