biochemistry 2 6

Tag: "biochemistry" at biology news

Major advance made on DNA structure

...rint for life. One of the fundamental problems in biochemistry is to predict the structure of a molecule from its sequence ?this has been referred to as the "Holy Grail" of protein chemistry. Today, the OSU scientists announced in the Proceedings of the National Academy of Sciences that they have used X-ray cry...

New tool reveals secrets of migrating cells

...'d take organs out, smush them up and basically do biochemistry in test tubes, or watch their behavior in a single layer of cells. It's an imaging revolution to be able to go into the native environment while keeping the intact organ alive and make movies of migrating cells." With two-photon imaging, Witt and Ro...

Biologists determine genetic blueprint of social amoeba

...eviously thought," says Adam Kuspa, a professor of biochemistry and molecular biology at Baylor College of Medicine in Houston and a senior author of the Nature paper. The discovery will also improve geneticists' understanding of how the genes from Dictyostelium and other genetic model organisms have been conser...

Scientists take aim at virulent bacteria by decoding machinery of key control enzyme

...tory in Chicago, Xiaodong Cheng, PhD, professor of biochemistry at Emory University School of Medicine and Georgia Research Alliance Eminent Scholar, and John Horton, PhD, Research Assistant Professor, have now solved the co-crystal structure of the Dam enzyme in complex with DNA, which has allowed them to observ...

Where Bacteria Get Their Genes

... said team member Howard Ochman, a UA professor of biochemistry and molecular biophysics and a member of UA's BIO5 Institute. The research also solves a long-standing evolutionary puzzle. Many scientists have argued that drawing traditional family trees does not make sense for bacteria, because their genomes rep...

The making and breaking of microtubules

...al Biosciences Division, an associate professor of biochemistry and molecular biology at the University of California at Berkeley, and a Howard Hughes Medical Institute Investigator. "We had previously produced high-resolution structures of stabilized tubulin structures, but nobody knew the structure of the trans...

Researchers discover key gene involved in bark beetle pheromone production

...tion," said Gary Blomquist, professor and chair of biochemistry and molecular biology, who co-authored with several members of his department an article that will be published this week(June 27 ?July 1) in the Proceedings of the National Academy of Sciences (PNAS). Bark beetles plague pine forests, especially wh...

High fidelity keeps human DNA assembly line humming

... nanotechnology in living systems and cutting-edge biochemistry and molecular biology with a system of checks and ...an development," said Zachary Burton, professor of biochemistry and molecular biology. "If you want to understand and control things like viral infections and tumor...

Researchers pioneer new gene therapy technique using natural repair process

...Dr. Porteus, assistant professor of pediatrics and biochemistry at UT Southwestern. "This is called selective advantage; the healthy cells grow and divide preferentially over the mutant ones." Previous gene therapy attempts for SCID have been only moderately successful because of technical difficulties in the de...

Chemical Engineer Kao Explores Antibiotic Synthesis With DNA Chips

...t developed a decade ago at Stanford in the lab of biochemistry Professor Patrick Brown, microarrays use both computer technology and DNA base pairing to track the expression of thousands of genes simultaneously. The technique has tremendous potential for the study of biological processes where numerous genes wor...

Where bacteria get their genes

... said team member Howard Ochman, a UA professor of biochemistry and molecular biophysics and a member of UA's BIO5 Institute. The research also solves a long-standing evolutionary puzzle. Many scientists have argued that drawing traditional family trees does not make sense for bacteria, because their genomes rep...

To Stop Evolution: New Way Of Fighting Antibiotic Resistance Demonstrated By Scripps Scientists

...an unstoppable force," says Romesberg. "There is a biochemistry underlying it and it is subject to intervention." The Scourge of Antibiotic Resistance One thing that scientists would like to change about bacteria and cancer cells is their changeability. At the dawn of the 20th century, bacterial infections acc...

Stanford gut check shows diversity of intestinal ecosystem

...les much more quickly. They have been working with biochemistry professor Patrick Brown, MD, PhD, and graduate student Chana Palmer to develop a gene chip that can perform a microbial census on complex communities and samples. ...

Molecular fossils uncover link between viruses and the immune system

...ogy, a new discipline integrating applied physics, biochemistry and biology, which have permitted detailed comparison of viral structures in atomic detail. Such comparison led to the discovery that viruses without any sequence homology may be related. Earlier approaches to delineate evolutionary history of virus...

Conserved amino acids play both structural and mechanistic roles in sandwich-like protein

...Pernilla Wittung-Stafshede, associate professor of biochemistry and cell biology. "Are they conserved to direct the protein-folding reaction, or are they selected to stabilize the final protein structure? In our paper, we unravel an unprecedented answer to this question." Wittung-Stafshede and graduate student C...

The biggest family tree ever

...gical research, said Cusanovich, a UA professor of biochemistry and molecular biophysics and a professor in BIO5. "If you ask around here, you find that every tenth person is building a little family tree at home. They go to all the records and they're using Web sites to trace back their history." The UA scienti...

After a time-shift, mixed signals from the circadian clock

...ian rhythms in mammalian behavior, physiology, and biochemistry are controlled by the central clock within a brain structure known as the suprachiasmatic nucleus (SCN). The clock is synchronized to environmental cycles of light and dark. It is well known, from everyday experience, that adjusting to new light sche...

UCLA scientists store materials in cells natural vaults

...ineering; Jeffrey Zink, professor of chemistry and biochemistry and Valerie Kickhoefer, first author and associate research biochemist. JOURNAL: The Proceedings of the National Academy of Sciences http://www.pnas.org/cgi/content/abstract/0500929102v1 ...

Biochemists report discovery of structure of major piece of telomerase; implications for cancer

...rks," said Juli Feigon, professor of chemistry and biochemistry at UCLA, who led the research group. "Knowing the structure also will allow the pursuit of rational, structure-based drug design, and is a critical first step. The structure provides a potential target for drug intervention." Feigon emphasized that ...

Disease diagnosis, biodefense among UH chemical research projects

...ification. # George Fox, professor of biology and biochemistry and professor of chemical engineering, and Willson, with several other authors, will present research on "Neutral additive effects on metal affinity adsorption of nucleic acids." Purification of nucleic acids (DNA and RNA) is important in diagnosing ...

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