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Tag: "biochemistry" at biology news

Gene therapy delivery of nerve growth factors reverses erectile dysfunction in animal model

.... Glorioso, III, Ph.D., chair of the department of biochemistry and molecular genetics, and Joel Nelson, M.D., chair of the department of urology, University of Pittsburgh School of Medicine, researchers inserted either the gene for the glial cell line derived neurotrophic factor (GDNF) or the GDNF family ligand ...

Simulations unravel outer membrane transport mechanism

...to and out of a structure like a beta-barrel, said biochemistry professor Emad Tajkhorshid, principal investigator on the study. “It’s very difficult to assess this experimentally because they have to look at the accessibility of certain (amino acids) before and after activation,” Tajkhorshid said. “And sometimes...

How sneaky HIV escapes cells

... highlights the importance of studying their basic biochemistry and cell biology, which can yield a better understanding of normal human biology as well as identify new avenues in the fight against human disease.” ...

Genome of yellow fever/dengue fever mosquito sequenced

...chemistry ( www.biochem.vt.edu ); James K Biedler, biochemistry postdoctoral associate; Song Li, research specialist senior in biochemistry; and Monique Royer Coy, biochemistry graduate student; and Chunhong Mao, senior project associate with the Virginia Bioinformatics Instit...

Link found between immune system and high plasma lipid levels

...hor Godfrey Getz, MD, PhD, professor of pathology, biochemistry and molecular biology at the University of Chicago. "This study may explain why. The next step would be to determine whether we can use this technique to manipulate the immune response and have a favorable impact on lipid metabolism." Using an ass...

Antifungal drug kills TB bug

... there are ‘unusual?aspects of its composition and biochemistry that set it apart from most other bacteria and that could provide new targets for antibiotic drugs. "When we began looking at the bug and its DNA content in more detail, we noticed it had some unusual characteristics. In particular, we noted the p...

Destructive enzyme shows a benevolent side

...R. Schoenberg, professor of molecular and cellular biochemistry and a researcher with Ohio State's Comprehensive Cancer Center. "By understanding how PMR1 and similar enzymes are incorporated into stress granules and inactivated, we may be able to learn how to block this protective mechanism and make it harder...

New study may show how to forestall a fatal, virus-caused immune-system meltdown

..., associate professor of pathology Judith Aronson, biochemistry and molecular biology instructor Heidi Spratt, and biochemistry and molecular biology professors David Gorenstein and Bruce Luxon. Funding for the investigation was...

RNA enzyme structure offers a glimpse into the origins of life

...illiam Scott, associate professor of chemistry and biochemistry at UC Santa Cruz. Scott and postdoctoral researcher Michael Robertson determined the structure of a ribozyme that joins two RNA subunits together in the same reaction that is carried out in biological systems by the protein known as RNA polymerase...

Jefferson researchers' discovery may change thinking on how viruses invade the brain

...uthor John Williams, Ph.D., assistant professor of biochemistry and molecular biology at Jefferson Medical College. "We found that while transport must happen ?it’s essential to viral infection and spread and disease progression ?it’s not through this mechanism. There’s more to the story." "We think we have to...

Williams College biologist explores photosynthetic apparatus

...ersity and received her Ph.D. in plant physiology, biochemistry and microbiology from Cornell. Following postdoctoral work at MIT, she joined the faculty at Williams College, where she has been teaching and conducting research since 2003. ...

Nanoparticles for delivery of prostate cancer treatment

...lan Garen , professor of molecular biophysics and biochemistry at Yale has received a $100,000 award from the Prostate Cancer Foundation to expand research on the delivery of a targeted therapy for prostate cancer using nanoparticles. Garen and his collaborator Zhiwei Hu have developed a way to directly tar...

Scientists reveal structure of gateways to gene control

...nism's genes," said B. Franklin Pugh, professor of biochemistry and molecular biology and the study's lead investi... Pugh and Stephan Schuster, associate professor of biochemistry and molecular biology, the Penn State research team then used antibodies that bind only to this H2A....

Antibiotic inhibits cancer gene activity

...rticipation of the late Robert Costa, professor of biochemistry and molecular genetics at UIC and a leader in research on FoxM1, was critical for the success of the project thus far. Senthil Radhakrishnan, a visiting bioinformatics expert at UIC, is first author of the paper. Uppoor Bhat, Douglas Hughes and I-C...

One-of-a-kind imaging probe reveals secrets useful for drug discovery

...id Arthur Edison, Ph.D., an associate professor of biochemistry and molecular biology. "In this case, it previously required hundreds of milkings to get enough walking stick venom for analysis. We were able to get great data from just one milking." Researchers at the McKnight Brain Institute's Advanced Magnetic ...

Stem cells engage in dialogue with the cells that regulate their futures

...che researcher Hannele Ruohola-Baker, professor of biochemistry and a member of the UW Institute for Stem Cell and Regenerative Medicine. "Demonstrating that stem cells can contribute to niche function has far-reaching consequences for stem-cell therapies and may provide insight on how cancer might spread through...

Selecting life: Scientists find new way to search for origin of life

...ults." David Deamer, professor of chemistry and biochemistry at U.C. Santa Cruz, commented that "Bob Hazen is boldly asking a fundamental question related to the origin of life. We know that organic compounds were present in the early Earth environment, but as dilute solutions of thousands of different species...

Nature's process for nitrogen fixation caught in action

...rtment of Chemistry and Biochemistry performed the biochemistry and the biophysics research was carried out in the Northwestern Department of Chemistry. An enzyme is a protein that induces chemical changes in another substance. "Such reactions involve several stages in the reduction pathway," Dean said. "Nitro...

American scientist's research of life's first cells

...of G.E. Schulz and this stimulated his interest in biochemistry and protein-crystallography. He continued to follow these interests by pursuing PhD work in the group of W. Saenger at the Free University Berlin, Germany. There, Loll elucidated the three dimensional structure of photosystem II, in work done in coop...

Proteins may behave differently in natural environments

...roscopy, Dr. Steven Ludtke, assistant professor of biochemistry and molecular biology and co-director of the National Center for Macromolecular Imaging at BCM, and colleagues from BCM and The University of Texas Southwestern Medical Center in Dallas, found such dynamic behavior in a mutant form of a protein calle...

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