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Tag: "biochemist" at biology news

New success in engineering plant oils

...al biotechnological applications," said Brookhaven biochemist John Shanklin, lead author on the paper. For one thing, the new tropical-like oil has properties more like margarine than do temperate oils, but without the trans fatty acids commonly found in margarine products. Furthermore, engineered oils could...

Scientists genetically engineer tomatoes with enhanced folate content

...beneficial worldwide," said Andrew Hanson, a plant biochemist at the University of Florida at Gainesville who developed the tomato along with colleague Jesse Gregory. "Now that we've shown it works in tomatoes, we can work on applying it to cereals and crops for less developed countries where folate deficiencie...

Scientists use nanoparticle to discover disease-causing proteins

...ples in a laboratory dish, said Andy Tao, a Purdue biochemist and senior author of the study. Because molecular interactions and protein functions are disturbed when samples are collected, researchers can't obtain an accurate picture of biochemical mechanisms related to illnesses such as cancer and heart diseas...

RNA enzyme structure offers a glimpse into the origins of life

...University of Texas, Austin, working in the lab of biochemist Andrew Ellington. Starting with a mixture of randomly synthesized RNA molecules and selecting for the desired properties, researchers are able to evolve RNA enzymes from scratch. In the Ellington lab, Robertson evolved the ligase ribozyme (called the...

Uncovering DNA's 'sweet' secret

...nsolvable - scientific mysteries. But Vanderbilt biochemist Martin Egli, Ph.D., isn't content to simplystudy these molecules as they are. He wants to know why they are the way they are. "These molecules are the result of evolution," said Egli, professor of Biochemistry. "Somehow they have been shaped and op...

Common ancestry of bacterium and plants could be key to an effective new treatment for chlamydia

...arles Gilvarg from Princeton University. "He's the biochemist who characterized the lysine pathway back in the 1950s, and so he had intimate knowledge about the steps of the pathway," said Leustek. "And he's the one that alerted us to the fact that plants do it differently. This is still the case, with the exce...

Public Library of Science to launch new, open access journal on neglected tropical diseases

...ord University and Howard Hughes Medical Institute biochemist Patrick Brown, and University of California at Berkeley evolutionary biologist Michael Eisen. Dr. Varmus said: "The launch of PLoS Neglected Tropical Diseases means that the latest knowledge on neglected diseases will be disseminated globally and w...

USC team reveals structure of APOBEC family protein

...nase protein, and a weakened immune system. USC biochemist Myron Goodman and his former graduate student Ronda Bransteitter collaborated with Chen's group to examine how the genetic mutations common in HIGM-2 patients might affect the structure, and therefore the function, of the AID enzyme. A professor of b...

Scientists' cell discovery unearths evolutionary clues

...sor Sandie Baldauf, of the University of York, and biochemist Professor Pauline Schaap, of the University of Dundee, have produced the first molecular 'dictionary' of the 100 or so known species of social amoeba. Using this family tree, they have devised a model system to establish how single cell organisms ...

Genetic snooze button governs timing of spring flowers

...rpinning of the familiar process of flowering, the biochemist emphasizes that much of the fine biochemical detail remains to be worked out. ...

Molecular DNA switch found to be the same for all life

...es, a collaborator on the Drosophila study. Said biochemist Michael Botchan, also a collaborator on the Drosophila study, "Our two papers fuse together a number of biophysical research techniques to take our understanding of the mechanics of DNA opening and replisome construction to a new level." Biochemis...

Research identifies protein in mice that regulates bone formation

...as forged a collaboration with Brandeis University biochemist Greg Petsko to find compounds that inhibit the two proteins, which could lead to new and better treatments for osteoporosis. Though the biggest hurdles of drug discovery lie in the distant future, said Petsko, "as early stage targets go, this looks p...

New understanding of COX-1 and COX-2 enzymes could revise classification of pain meds

...ew heterodimer. Dr. Funk's co-researcher, Queen's biochemist Robert Campbell, has developed a computer model to show how the COX-1/COX-2 molecules can associate. "It's possible the COX-2 inhibitor medications may affect the resulting new enzyme which is a mix of COX-1 and COX-2," says Dr. Funk. This effect...

Study may help slay 'Yellow Monster'

...store nature's balance.Northern Arizona University biochemist Diane Stearns and her Navajo students are not only gaining knowledge, they are adding to that knowledge with new discoveries about uranium. The fact that uranium, as a radioactive metal, can damage DNA is well documented. But what Stearns and her co...

Polymer aids in blood clotting, pointing way to new treatment

... three important roles, said James H. Morrissey, a biochemist in the U. of I. College of Medicine at Urbana-Champaign. The inorganic compound accelerates two parts of the coagulation cascade -- the contact-activation pathway and factor V, a protein that forms thrombin -- leading to fibrin and clots. Finally, he...

Researchers unravel DNA tangles and enzyme seamstresses

...NA in cancer cells and kill them off," says U of T biochemist Hue Sun Chan, the study's co-author and a Canada Research Chair in proteomics, bioinformatics and functional genomics.The study is co-authored by Professor Lynn Zechiedrich of Baylor College of Medicine in Houston, Texas, who proposed the notion in a...

Heart-healthy compound in chocolate identified

... cardiovascular function in humans," said UC Davis biochemist Hagen Schroeter, who co-authored the paper along with cardiologist Christian Heiss of the Heinrich-Heine University. "The results of this study provide direct proof that epicatechin is, at least in part, responsible for the beneficial vascular effec...

Scientists develop protein-sequence analysis tool

...ational 'wheat' from the 'chaff,'" said Brookhaven biochemist John Shanklin, who leads the research team. The program, which is described in the open access journal BMC Bioinformatics*, makes comparisons of groups of related proteins and flags individual amino acid positions that are likely to control function....

Nanoparticles, nanoshells, nanotubes: How tiny specks may provide powerful tools against cancer

...es Detect Breast Cancer Cells (Abstract 3126) A biochemist and an engineer have used tiny carbon nanotubes and monoclonal antibodies to detect cancer cells in the laboratory dish. The work might lead to nanotube-based biosensors that can spot circulating cancer cells in the blood from a new cancer or from a ...

Seaweed yields new compounds with pharmaceutical potential

... category of organic molecules. It's exciting as a biochemist to observe that living organisms have evolved the ability to synthesize such unique and exotic structures compared to other molecules typically produced by seaweeds." The source of these new molecular structures is a red seaweed (Callophycus serratu...

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