Max Planck researchers make a breakthrough in plant stem cell research
...62;TM s team now carried out elaborate genetic and biochemical experimentation, and thereby identified four genes, which might serve as a mechanistic connection between plant hormones and the genetic regulatory elements in meristem. The researchers in Tübingen used gene expression analysis to show that the gen...Bacterial protein mimics host to cripple defenses
...otein works at the molecular level. "We had some biochemical clues to what AvrPtoB was doing, but getting the three-dimensional crystal structure was really key," Martin explained. To find that structure, Martin and Abramovitch worked with collaborators at Rockefeller University. The structure of AvrPtoB revea...Plant gene related to cancer treatment may foster new oncology drugs
...ells, send messages from cell to cell to influence biochemical reactions, and to regulate those reactions. The ABC proteins are so named because they must bind with ATP, the main cell energy source, in order to fulfill their mission. The best known member of another class of transport proteins, PIN1, also may b...Student scientists create living bacterial photographs
...convert light images shined onto the bacteria into biochemical prints. To create the photographs, the Texas students used a unique light projector largely designed and built by Chevalier, a physics undergraduate. The device projects the pattern of light--like an image of one of the Texas students' co-advisers,...Scientists characterize proteome of human cornea
...of corneal disorders. "It is essential to know the biochemical composition of normal healthy corneas in the effort to understand the molecular mechanisms behind corneal disorders," emphasizes Dr. Enghild. "By comparative proteomic studies of diseased and normal corneas we can identify differences in the expressi...Researchers learn how blood vessel cells cope with their pressure-packed job
...equivalence and cooperation between mechanical and biochemical stimuli to regulate the proper orientation of these stress fibers," said Kaunas. "Indeed, we found that the stress fibers oriented in such a way to control their level of stress ?not too little and not too much." Chien and Kaunas collaborated with U...Biotechnology's newest chemical tool
...e approach will not only help reveal the impact of biochemical alterations to DNA, but could have far-reaching implications for DNA-based medical diagnosis and nanobiotechnology. Combining chemistry with biotechnology, Saulius Klimasauskas, a Howard Hughes Medical Institute (HHMI) international research schol...Scientists develop nanotech-laser treatment that kills cancer cells without harming healthy tissue
...is co-workers achieved this by performing a bit of biochemical trickery. Unlike normal cells, the surface of a cancer cell contains numerous receptors for a vitamin known as folate. The researchers decided to coat the nanotubes with folate molecules, which would only be attracted to diseased cells with folate re...Gene therapy reverses genetic mutation responsible for heart failure in muscular dystrophy
...l protein almost a year later. There were dramatic biochemical and structural improvements in muscle cells in both groups as well. This was accompanied by markedly improved skeletal and cardiac muscle functions. Indeed, the newborn-treated hamsters had completely normal hearts, when examined at eight and one-ha...New study to explore cellular circuitry
...o determine which protein is involved in any given biochemical process. Only the tagged protein involved in a given reaction will show up in the results of specially designed tests. A second potential application of the library relies on its clones' ability to produce large amounts of protein, which can help ...Prions rapidly 'remodel' good protein into bad, Brown study shows
...nfirmed in a series of experiments using different biochemical and genetic techniques. Because proteins can't replicate like DNA and RNA ?the genetic material in bacteria, viruses and other infectious agents ?the research helps explain the puzzling process of how prions multiply and spread infection. Satpute-K...Biologists Crack Genetic Code for Specialized Spider Silk
... diagnose these patients, it provides clues to key biochemical pathways that can lead to immunodeficiencies.?/p> The study was led by Raif Geha, M.D., and Emanuela Castigli, Ph.D., of the Children’s Hospital Boston. The Boston team found specific mutations in a gene known as TACI, which plays a specific role...US/African project deciphers deadly parasite genome
...says scientists found that T. parva "lacks several biochemical pathways that are present in the malaria parasite, suggesting that Theileria is more dependent on its host for nutrients." Gardner, who was also the first author of the 2002 paper on the genome of the deadliest human malaria parasite, says that seve...Agreement will speed research on microbicides for women
... diagnose these patients, it provides clues to key biochemical pathways that can lead to immunodeficiencies.?/p> The study was led by Raif Geha, M.D., and Emanuela Castigli, Ph.D., of the Children’s Hospital Boston. The Boston team found specific mutations in a gene known as TACI, which plays a specific role...Purdue researchers find key to rice blast fungus
...instructions from one molecule to another to cause biochemical changes. The fungus spreads when its spores are blown to rice plants and stick on the leaves. Once on the plant, the spore forms a structure called an appressorium. This bubble-like structure grows until it has so much pressure inside that it blasts...Defective Gene Linked to Two Inherited Immune Deficiencies
... diagnose these patients, it provides clues to key biochemical pathways that can lead to immunodeficiencies.?/p> The study was led by Raif Geha, M.D., and Emanuela Castigli, Ph.D., of the Children’s Hospital Boston. The Boston team found specific mutations in a gene known as TACI, which plays a specific role...UT Southwestern researchers discover master switch in cell death
...ons, controlled by a few molecules that sit atop a biochemical “pyramid.?/p> The newly discovered enzyme, which the researchers have named Mule, destroys a key molecule at the top of the pyramid, thus leading to the cascading disintegration of the cell. Their findings also suggest a new drug target for contr...Most embryos produced during IVF do not result in live births
...clude using pre-implantation genetic diagnosis and biochemical markers of embryo viability," said Patrizio. "In addition this study should also move the field toward perfecting methods of egg production." ...Neurotransmitters signal aggressive cancer, offer potential for early diagnosis
...that the tumors made GABA using a different set of biochemical reactions than normal. Key enzymes involved in the production of these compounds were switched on in poor prognosis malignant metastatic tumors. "The mouse model was an important beginning point for our investigation," says the study's lead author J...MSKCC researchers uncover structure of key protein complex in cells
...of the contacts observed in our structure with the biochemical activities and effects on the cell itself of disrupting these contacts," Dr. Lima said. He and his colleagues are now studying these interactions in yeast. ...