Inflammatory molecules released by pollen trigger allergies
...of Experimental Medicine puts some of the blame on bioactive molecules that are released from pollen. These molecules bind to immune cells and cause them to launch a typical allergy-promoting immune response. Pollen from plants exposed to air pollutants produce more of these allergy-provoking compounds than do...Researchers discover chemical compounds that affect plant growth
... as endomembrane trafficking. "Well-characterized bioactive chemicals and their targets identified in the model plant, Arabidopsis, can be used in non-model species to improve agronomic traits and increase crop value," said research team leader, Distinguished Professor of Plant Cell Biology Natasha Raikhel. ...Chemical Engineer Kao Explores Antibiotic Synthesis With DNA Chips
...cuses on, the actinomycetes, produces thousands of bioactive molecules, with many more discoveries sure to come. "When new molecules are discovered to be made by species of this family, the research we do will hopefully be used to quickly make mutant strains that make a lot more of it," she said. "No drug com......concluded that the sponges concerned produce their bioactive substances to defeat spatial competitors. This is important, as in an environment without spatial competitors, such as in a sponge culture, a lower concentration of the substances of interest to the pharmaceutical industry might be produced. Sponge ...Protein synthesis can be controlled by light, opening way for new scientific, medical applications
...light-sensitive molecule called a chromophore to a bioactive molecule called an effector through a single covalent bond that inactivates the bioactive molecule. Exposing the caged compound to light releases the effector in its active form. "It's anal...Modified collagen could yield important medical applications
... treatments, Yu says, because it is easy to attach bioactive agents to the peptides. When the peptides bind with collagen, these attached agents can dramatically change the way collagen behaves in the body. For example, collagen normally attracts cells to close up a wound and form scar tissue. But this propert...Unusual antibiotics show promise against deadly 'superbugs'
... treatments, Yu says, because it is easy to attach bioactive agents to the peptides. When the peptides bind with collagen, these attached agents can dramatically change the way collagen behaves in the body. For example, collagen normally attracts cells to close up a wound and form scar tissue. But this propert...Natural compound from 'pond scum' shows potential activity against Alzheimer's
...izes in identifying, synthesizing and studying new bioactive compounds from natural sources. There is no cure for Alzheimer's at present, although cholinesterase inhibitors have shown promise for delaying or preventing the symptoms of mild to moderate forms of the disease, experts say. The newly isolated comp...Scientists use stem cells to grow cartilage
...lage. The cells were then implanted in mice on a bioactive scaffold for 35 days. When they removed the scaffo...ial College. The team had previously developed the bioactive scaffold which was used as a scaffold to grow the stem cells on. Dr Anne Bishop, from Imperial Coll...Mining for gems in the fungal genome
...not required for life. "Secondary metabolites are bioactive compounds that are only produced at select times during the life cycle of the organism," explains Keller, noting that the compounds can help fungi survive various environmental stressors. Some secondary metabolites have powerful heath effects in h...Bioactive cement scaffold may improve bone grafts
...can tell the difference between materials that are bioactive compared to bioinert polymers. Our material is designed to be similar to mineral in bone so that cells readily attach to the scaffold." The researchers used mouse bone cells in their experiments, but in practice surgeons would use cells cultured from...When the going gets tough, slime molds start synthesizing
...chinery that makes the essential precursor for the bioactive DIF-1 molecule.' " Kay replied that he and co-lead author Tamao Saito, PhD., a scientist on sabbatical in his lab, had also focused on these unusual type III PKS genes following the recently completed final assembly and annotation of the entire Dic...Breastfeeding boosts mental health
...Dr Wendy Oddy said there was growing evidence that bioactive factors in breast milk played an important role in the rapid early brain development that occurs in the first year of life. "Even when we adjust the results to take into account other factors such as the parents' socio-economic situation, their ed...Cloning techniques produce FDA-approved antibiotic
... cell wall. "Phosphonic acids are underexploited bioactive compounds with great potential for treating human disease," said Huimin Zhao, a U. of I. professor of chemical and biomolecular engineering. "We hope to understand the complete pathway for how fosfomycin is made." In a paper to appear in the Nov. 2...Friendly bacteria in alcoholic milkshake could fight food allergies
...n out the certain components (bacterial strains or bioactive peptides) from kefir and utilize them in medicine," he said. Also in this weeks Chemistry & Industry, UK firm Rigest are looking for backers to develop an air sanitizing system using an enzyme found naturally in human tears. Lactoperoxidase ca...Tissue engineering for craniofacial reconstruction
... paradigm combines isolated cells with appropriate bioactive agents in a biomaterial scaffold. It is widely recognized that scaffold architecture can profoundly influence the behavior of cells on tissue-engineering constructs. Today, during the 85th General Session of the International Association for Dental ...Fat screen delivers plant-derived chemical with antidiabetic effects
...a technologically advanced screen of more than 500 bioactive compounds, the researchers found that harmine has such a positive effect on fat. The fat cells under examination were manipulated such that they literally lit up when fat-boosting PPARã became active. Further study of harmine's effects in diabetic...