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Tag: "beta" at biology news

Brain inflammation may be friend, not foe, for Alzheimer's patients

...The team used a lentivirus to boost levels of IL-1 beta in select brain regions of its engineered mouse, then applied the technology in mice specially designed to develop Alzheimer’s disease. The mice developed normally for six months. Then Shaftel raised the level of IL-1beta in one part of the brain ...

Newly found sensing system enables certain bacteria to resist human immune defenses

... study its response to a specific human AMP, human beta defensin 3. S. epidermidis is one of several hard-to-treat infectious agents that can be transmitted to patients in hospitals via contaminated medical implants. Findings by Dr. Otto’s research group are published in the May 29 issue of the Proceeding...

Newly discovered antibody may be body's natural defense against Alzheimer's

... found antibodies selectively target aggregates of beta amyloid proteins called "oligomers" that are toxic... to contain small quantities of antibodies against beta amyloid. "The effects of IVIG in lowering beta amyloid levels in Alzheimer's patients in our Pha...

Pistachios lower cholesterol, provide antioxidants

...utein, ?normally found in dark leafy vegetables -- beta carotene ?a precursor to vitamin A ?and gamma tocopherol ?the major form of vitamin E ?than other nuts. It is oxidized LDL and other lipproteins that contribute to plaque formation in arteries. The researchers reported that both the 1.5 and 3 ou...

Statin treatment improves spatial memory in mouse models of Alzheimer's

... used in the study are homozygous for the gene for beta amyloid protein, making it inevitable that they de...se animals, together with regular mice without the beta amyloid genes, were acclimated for one week, with as much food and water as they wished, then divide...

Nitric oxide: Key to cardiovascular and pulmonary function and drug effectiveness

...rs to control whether certain medications, such as beta adrenergic receptor agonists used in acute heart f...that a lack of nitric oxide leads to a decrease in beta adrenergic receptor number and function. Also, the researchers found that when SNO compounds were ad...

UCLA AIDS Institute researchers find a peptide that encourages HIV infection

...eties of peptides, also known as defensins ?alpha, beta and theta, Lehrer said. Humans have only alpha and beta; monkeys have all three. "Here's a peptide whose normal structure allows it to protect against viruses, yet if you make the same peptide and place its amino acids in a reverse order, that let...

No magic tomato? Study breaks link between lycopene and prostate cancer prevention

...xpected observation "may be due to chance, however beta carotene is already known to increase risk of lung...egetables, I would say to be cautious about taking beta carotene supplements, particularly at high doses, and consult a physician," Peters said. ...

Gut research yields new anti-cancer approach

...ubules are made of two related proteins, alpha and beta tubulin, which pair up to form a chain and then wi...e PPARgamma inhibitors reduced levels of alpha and beta tubulin by 60 to 70 percent. Also described in the publication are studies where PPARgamma inhibitor...

Stress may help cancer cells resist treatment, research shows

... "A study from Canada showed that men who took beta blockers for hypertension for at least four years had an 18 percent lower risk of prostate cancer," said Kulik. "These drugs block the effects of epinephrine, which could explain the finding. Another study of men after radical prostatectomy reported...

Cold sore virus might play role in Alzheimer's disease

...at the gene plays a role in clearing toxic amyloid beta from the brain. "Just how ApoE-4 makes people vulnerable to Alzheimer's disease isn't resolved at all," said Federoff, who is director of the University's Center for Aging and Developmental Biology. "It may be that it works in multiple ways." T...

Turning green gunk to gold, anti-cancer gold

.... Scientists have known for several years that the beta configuration was absolutely required for the anti... that always introduces the epoxide in the desired beta configuration. Sherman, who is also the John G. Searle Professor of Medicinal Chemistry in the Co...

Protein overexpression at heart of heart failure

...a2+-channel pore. The causal role of the increased beta 2-subunit expression for the “heart failure type?o...eveloped a novel, cardiac-specific, drug-inducible beta 2a subunit overexpression transgenic mouse which was crossbred with the channel pore overexpressing ...

Elucidation of the genome for diabetics with DNA chips

...ulin produced exclusively in the insulin-secreting beta cells of the pancreas. Zinc is a trace element present in very small amounts in the body, but essential for survival. Zinc deficiency is common in developing countries and has been associated with many diseases, including dabetes. These four gen...

Scientists find new genetic clue to cause of Alzheimer's disease

...ecursor protein, or APP, is processed into amyloid beta protein fragments that make up plaques in the brai...nts that demonstrate SORL1's role in production of beta amyloid fragments. Examining blood cells from people with and without Alzheimer's, the researcher...

Unique tomatoes tops in disease-fighting antioxidants

...lycopene, and a tomato variety chosen for its rich beta carotene content. The tomatoes were grown at an...ther featured sauce made from the tomatoes high in beta carotene. The participants were asked to avoid tomato and beta carotene-rich foods for 13 days befor...

Researchers seek to design first treatment for neuroAIDS

...ant, drugs that inhibit glycogen synthase kinase 3 beta (GSK-3b) and mixed lineage kinase (MLK). "The number of HIV patients that suffer brain damage is usually estimated at one in five, but I believe that nearly all of them, if they live long enough, will be affected," said Harris A. Gelbard, M.D., Ph.D...

The power of one: A simpler, cheaper method for cell fusion

...ng hybrid, called a hybridoma. By manipulating the beta cells prior to fusion, scientists can create thousands of different hybridomas that produce antibodies effective against different viruses and diseases like cancer. Lu's research regarding the development and use of this technology was published o...

Molecules in blood foretell development of preeclampsia

...ly, a molecule known as transforming growth factor beta (TGF beta) binds to endoglin, and this binding is ...Dr. Levine added, so that more VEGF, PlGF, and TGF beta would be available for the blood vessels that need them. One company has developed the means to pro...

Molecular 'signature' protects cells from viruses

...or example, they then produce what is known as the beta interferon, thereby activating specific killer cells. They also initiate the cell's suicide programme ?apoptosis. The viruses cannot then continue to breed.' Up to now it was not known how cells distinguish their own RNA from that of the 'enemy'. ...

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