Engineered molecule amplifies body's immune response
...of interferon by enhancing the way it produces its beneficial effects. We therefore improved a molecule, known a... in which interferon hyper-responsiveness might be beneficial will profit from Dr. Holtzman's research. "One could use our strategy of improving Stat1 efficiency...NIH renews network focused on how genes influence drug responses
...ially fatal irregular heartbeats (arrhythmias) are beneficial to some people and harmful to others. (Dan M. Roden, M.D., Vanderbilt University) The Amish Pharmacogenomics of Antiplatelet Intervention Study --$7.5 million provided by NIGMS to characterize the genetic basis for why people respond different...Say what? Bacterial conversation stoppers
...ostdoctoral fellow Karina Xavier mixed E. coli, beneficial bacteria that live in the human gut, with Vibrio harveyi, a marine species that naturally glows in the dark in the presence of a crowd. In the test tube, AI-2 production by either species turned up the marine bacteria's light and turned on the quo...New lifespan extension genes found
...rence. Deleting Hst2 and Sir2 blocked most of the beneficial effect of caloric restriction. When Hst2 was overexpressed, so that the gene was more active than normal, the yeast lived longer than normal. A third gene, Hst1, appears to act when both Sir2 and Hst2 are missing. Sir2 and the newly identified Hst g...Hepatitis C responds best to combo of ribavirin and interferon, study concludes
...ia; difficulty breathing, cough and fatigue. "The beneficial effect of adding ribavirin to interferon is not fu...ors conclude. "Ribavirin might have an independent beneficial effect on chronic hepatitis C, in addition to interferon, or might have a beneficial effect on patie...Compound might defeat African sleeping sickness, clinical trial beginning this month
...rotects the nervous system naturally but can block beneficial drugs, he said. Work is also progressing rapidly on a new drug for drug-resistant malaria, another major threat in developing countries. The UNC-led Consortium to Develop New Drugs for Protozoan Diseases established an advisory board chaired by Dr. ...Caloric restriction won't dramatically extend life span in humans: UCLA research
...estriction is likely to be almost universal in its beneficial effects on longevity, the benefit to humans is going to be small, even if humans restrict their caloric intake substantially and over long periods of time." Phelan developed the first mathematical model demonstrating the relationship between caloric...Researchers discover mechanism for multiplying adult stem cells
...ld grow into healthy tissue." "This could be very beneficial for burn victims," Jaenisch adds. Researchers in his lab are also exploring whether activating Oct4 in somatic cells, such as skin cells, would make it easier for these cells to be reprogrammed when used as donors for nuclear transplantation. If so,...Diabetic nerve therapy shows 'striking' results
... produce a natural version of this therapeutically beneficial protein. The most significant advantage of this is that the protein is made as if the patient's body had made it naturally. "Our study has shown that a single treatment with a DNA-binding protein protected against nerve damage that in humans can lea...Novel live reporting system to track cells
... ferritin as a reporter gene would be particularly beneficial in those cases where administration of contrast material is compromised by barriers, including embryonic development and the central nervous system." ...Genome study of beneficial microbe may help boost plant health
...y's first author. The use of naturally-occurring, beneficial microbes such as P. fluorescens to control plant p...ng synthetic fungicides. In all, about three dozen beneficial microbes are currently used as an environmentally-friendly way to fight plant diseases. Joyce E. Lo...Chronic Sinus Infection Thought To Be Tissue Issue, Mayo Clinic Scientists Show It's Snot
... implications," says Dr. Ponikau. "This suggests a beneficial effect in treatments that target primarily the underlying and presumably damage-inflicting nasal and sinus membrane inflammation, instead of the secondary bacterial infection that has been the primary target of treatments for the disease. Also, some ...Experiment station researchers to explore genome of disease-fighting fungus
...sequencing work may uncover chemical compounds and beneficial genes useful in producing new human and animal antibiotics. The sequencing project is a collaborative effort with the Department of Energy Joint Genome Institute. Experiment Station plant pathologists are Drs. Charles M. Kenerley, Daniel J. Ebbole, ...U. Iowa researchers improve Huntington's disease symptoms in mice
...erapy designed to inhibit protein production has a beneficial effect." The study will appear this week in the O... partial reduction is sufficient to produce a very beneficial effect in the animal. It means that we don't have to turn the gene off completely," Davidson said. "...Researchers test new therapy for advanced melanoma
... Heller said. "We're hoping this translates into a beneficial treatment for patients." The Phase 1 clinical trial by Moffitt and Genetronics Biomedical Corp is evaluating the safety of the electroporation technology in treating patients with advanced melanoma. The trial expects to enroll 18 to 25 patients. ...Chemical Engineer Kao Explores Antibiotic Synthesis With DNA Chips
...ink of a genome as a deck of cards, and inducing a beneficial mutation as slipping in a joker. It's easy to see ... get a deck with 20 jokers--or a bacterium with 20 beneficial mutations. "In one year we should be able to generate a high producer that's equivalent to 20 years...Stealth Worms May Improve Insect Pest Control
...e been demonstrated not to harm humans, livestock, beneficial insects or the environment. Nematodes usually have to be underground; their targets are soil insects." The formulations keep improving as newer isolates of nematodes are found, and there is a lot of commercial interest in matching nematodes to pests...Brain May Be Less Plastic Than Hoped
...e and study reorganization that may turn out to be beneficial in the future.?/p>...A little stress gives beneficial oomph! to immune system
... brief bout of stress can give the immune system a beneficial boost ?under certain conditions. Laboratory results showed that acute stress ?stress that lasts for minutes to hours ?temporarily mobilized all major types of immune cells, or leukocytes to potential battle stations in the body. In certain situation......he evolution of sex, they said. "Sex is generally beneficial as a means to produce offspring with different gene combinations that can adapt more rapidly to new environments," said HHMI investigator Joseph Heitman, M.D., Ph.D., of Duke, senior author of the study. "The findings suggest for the first time that...