DNA ends: Common tool, different job
...ical experiments which revealed that Stn1 and Ten1 behave just like their counterparts in the conventional RPA complex. However, Stn1 and Ten1 have the same predilection for single-stranded telomeric DNA as Cdc13, thereby helping to ensure that this complex only targets chromosome tips. According to Lun...Researchers create artificial enzyme that mimics the body's internal engine
...ing it into two molecules of water. "CcO has to behave perfectly," Collman said. "If it adds less than four electrons, it can produce partially reduced oxygen molecules, and these are known to be very toxic." The two most deleterious forms of reduced oxygen are superoxide and hydrogen peroxide, which hav...Scientists use nanoparticle to discover disease-causing proteins
...ting or hemorrhage. Understanding how the proteins behave could help determine predisposition to heart disease and cancer and also be useful in diagnosis and drug development. In future research, Tao plans to investigate how dendrimers are able to enter the cell so easily, what happens to them once they ...Liver regeneration may be simpler than previously thought
...that cells that participate in tissue regeneration behave as if they were part of a growing organ in an embr...o interested in testing whether regenerating cells behave like embryonic ones, as is commonly assumed for other organs. New processes may explain why the live...Genetic pathways to curable and incurable forms of pancreatic cancer identified
...t explains this sequence and details why the cells behave differently. "Although at their end stage the two different routes to ductal pancreatic cancer can look very much the same under the microscope, involve the same constellation of genetic events, and culminate in invasive and metastatic disease th...Good behavior, religiousness may be genetic
... individuals do have biological predispositions to behave in certain ways," says Koenig. "The use of twins in the current study allowed for an investigation of the genetic and environmental influences on this type of behavior." This research is another example of the way that genes have an impact on beh...Man's best friend lends insight into human evolution
...heir impulse to fear more dominant individuals and behave aggressively toward more subordinate ones. "Taken together," Hare writes, "the results on chimpanzee cooperation and their use of social cues support the hypothesis that evolution in human social problem solving, much like that of dog social prob...Switching genes to overdrive improves muscular dystrophy symptoms in mice
...d increase the activity of genes that are known to behave abnormally in muscular dystrophy. PGC-1alpha is known as a “transcriptional coactivator?that functions as a switch, or perhaps more accurately, like a light dimmer that increases or decreases the activity of genes under its control. Exercising a m...Growing nerve cells in 3-D dramatically affects gene expression
...e that cells cultured in three dimensions look and behave more like cells in your body," said Diane Hoffman-...some scientists suspect that hothouse cells do not behave like in vivo varieties. This means that the critical functions scientists are trying to understand b...Iowa State scientists demonstrate first use of nanotechnology to enter plant cells
...nt cell (called making protoplasts), forcing it to behave like an animal cell and swallow the nanoparticle. It didn’t work. They decided instead to modify the surface of the particle with a chemical coating. "The team found a chemical we could use that made the nanoparticle look yummy to the plant cel...Physicist cracks women's random but always lucky choice of X chromosome
...ider implications as at least 10% of our genes may behave in similar ways as mechanism that "chooses" between X chromosomes. Examples of this range from the immune system to our olfactory apparatus. Coming at the problem from the perspective of a physicist Dr Nicodemi has found an explanation for the ran...