UCLA study finds same genes act differently in males and females
UCLA researchers report that thousands of genes behave differently in the same organs of males and females ?something never detected to this degree. Published in the August issue of Genome Research, the study sheds light on why the same disease often strikes males and females differently, and why the ge...Robots manipulating animal behaviour
...eral answers. Firstly, by changing the way animals behave or inducing collective behaviour, scientists can learn much about animal communications and information processing. Secondly, the ability to create 'mixed systems', where artificial agents interact with natural ones, is a long-held dream for many in ...MIT engineers probe spiders' polymer art
...nt of Mechanical Engineering. Non-Newtonian fluids behave in strange and unexpected ways because their viscosity, or consistency, changes with both the rate and the total amount of strain applied to them. Spider silk is a protein solution that undergoes pronounced changes as part of the spinning process....Fat stem cells being studied as option for breast reconstruction
...ived stem cells taken from a breast cancer patient behave no differently than those from other women. Moreover, our studies will seek to understand what effect, if any, these stem cells may have on cancer cells. A major question is whether they will in some way promote the growth of cancer cells. We certain...MIT creates 3-D scaffold for growing stem cells
... get a more accurate picture of how cells grow and behave in the body, the new synthetic structure can provi...he scaffold can be fashioned to coax stem cells to behave in certain desirable ways-such as differentiating into needed body tissues or migrating toward bone ...Innovative movies show real-time immune-cell activity within tumors
...umor microenvironment. How would the green T cells behave in the two groups of mice? "In the animals that received the vaccination, we saw two waves of activity after the T cells entered the tumor microenvironment," Weninger says. "Early on, the T cells didn't actively migrate through the tissue. This, w...Fighting like a girl or boy determined by gene in fruit flies
...tic tricks," she said, "and flies in many respects behave and respond similarly to humans." The findings provide a welcome guidepost to help enable future research to track down the underlying neural circuitry, said Bruce Baker, a biology professor at Stanford who first linked the fruitless gene to male-...Human stem cells delay start of Lou Gehrig's disease in rats
...arn as much as possible about how human stem cells behave when transplanted. ...Report calls for improved monoclonal antibodies against solid tumors
...ed how antibodies, including monoclonal therapies, behave in the human body; to understand how and how often therapies should be administered. Given these advances in our knowledge, the authors write, “an equally large number of antibody construct and therapy variables are available for optimization inc...Supercomputing equipment to advance the frontiers of computational biology
...nd how proteins, DNA, and other biological systems behave at the molecular level, according to the Rensselaer research team. The new SUR award is designed to help develop simulations for prototyping medical devices in "virtual patients," with potential applications in targeted drug delivery systems such as ...One signal elicits thousands of answers
...han one phosphorylation sites, which in many cases behave differently. "This makes more than one way of phosphorylation possible where proteins serve as integrating platforms for a variety of incoming stimuli", says Mann. "This integration of signals could be independent, with phosphorylation of each site o...Natural protein stops deadly human brain cancer in mice
...ces positive changes in the activity of cells that behave like cancer stem cells. The report is published this week in Nature. The most common type of brain cancer-glioblastoma-is marked by the presence of these stem-cell-like brain cells, which, instead of triggering the replacement of damaged cells, form...Molecular 'marker' on stem cells aids research, perhaps therapies
... to cancer stem cells, those cells in a tumor that behave like stem cells in that they self-renew and maintain the cancer even if most of the tumor is destroyed by radiation or chemotherapy. “Is the expression of this marker elevated in a tumor" If so, perhaps it might be useful to identify cancer stem ...Math model predicts cancer behavior
...les of molecules that suggest how tumor cells will behave ?are not entirely predictive, he added. Quaranta and colleagues opted for a new approach ?using the tools of mathematics to tackle the complex problem of cancer behavior. "We have mathematics driving experimentation," Quaranta said. The team wil...Living view in animals shows how cells decide to make proteins
...ch more complete picture of how genes and proteins behave than do experiments using cells in culture." U...is most relevant in a living animal, because cells behave differently in their natural environment versus an artificially created environment such as a labora...Penn researcher shows that DNA gets kinky easily at the nanoscale
... looked at long chunks of DNA, it always seemed to behave like a stiff elastic rod." For example, DNA must wrap itself around proteins, forming tiny molecular structures called nucleosomes, which help regulate how genes are read. The formation of tight DNA loops also plays a key role in switching some ge...Breathing easy: When it comes to oxygen, a bug's life is full of it
...lopment, has also studied how oxygen-starved cells behave in developing airways. Krasnow’s laboratory is also investigating the development of the mammalian lung using mice. The work is aimed at learning more about human lung diseases and developing ways to reactivate lung development to restore diseased ti...Coated nanoparticles solve sticky drug-delivery problem
...the mucus barrier." To make their nanoparticles behave like viruses, the researchers coated them with polyethylene glycol, PEG, a non-toxic material commonly used in pharmaceuticals. PEG dissolves in water and is excreted harmlessly by the kidneys. The researchers also considered the size of their n...Lower carbon dioxide emissions from coal-fueled power plants possible with technology development
...bon dioxide captured using Rochelle’s process will behave if stored underground in a high-pressure, liquid form. Sandstone formations common in Texas and some other states are already being considered nationally for this type of storage. Colleagues at the Jackson School’s Bureau of Economic Geology will ...Cancer tip -- Nanoparticles can damage DNA, increase cancer risk
...achusetts. Yet very little is known about how they behave in the environment or how they interact with and affect humans. "Unfortunately, only a very small portion of research on nanoparticles is focused on health and safety risks, or on threats to the environment," Pacheco said. "I am concerned becaus...