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Cells re-energize to come back from the brink of death

...cells that avoided CICD took about a week or so to begin multiplying again,” Green said. “This might represent the time it takes for the cell to restore enough mitochondria to allow the cell to function normally.” The discovery that GAPDH appears to save cells from CICD suggests that blocking this enz...

Bigger horns equal better genes

...However, once the ibex mature to the age when they begin competing for reproductive mates (7 to 12), horn length varies according to genetic diversity: the greater the diversity, the greater the length of the horns. The researchers believe the horn length discrepancies are evidence to support the muta...

Brightening prospects of using fluorescent nanotubes in medical applications

...t the brightest ones, I hope that researchers will begin considering ways to use them in clinical applicati...roteins – widely used for imaging living systems – begin fading within a few hours. Quantum dots last several days before degrading. Hertel’s team is curr...

Now, self-healing materials can mimic human skin, healing again and again

...eate their self-healing materials, the researchers begin by building a scaffold using a robotic deposition process called direct-write assembly. The process employs a concentrated polymeric ink, dispensed as a continuous filament, to fabricate a three-dimensional structure, layer by layer. Once the scaf...

Undergraduate research shows leaderless honeybee organizing

...d becoming more active. At this point, the workers begin to send a second signal that researchers call “worker piping” at a fevered pitch. Piping, which consists of bees making contact and vibrating their wing muscles rapidly, appears to be a general instruction to fly. The researchers document that the...

Helping chlorine-eating bacteria clean up toxic waste

...odels," she said. "As we develop the model, we can begin to look at the genomes of other strains of Dehalococcoides. If genes that are important in our strain are found in others ... then we can do the same experiments with the others." Finding which genes are at work with which pollutants might lead to un...

New vaccine prevents CMV infection and disease in mice

...ce,” Morello said. Researchers at UCSD hope to begin pre-clinical work on development of a human vaccine. If successful, an FDA-approved, commercially licensed hCMV vaccine could be administered to specific at-risk populations, such as females prior to child-bearing years, day care providers, organ tr...

Adult stem cells from human cord umbilical cord blood successfully engineered to make insulin

...e pancreas were used to direct adult stem cells to begin developing, or "differentiating," into islet-like cells. As they grew these adult stem cells in the laboratory, the researchers conducted other tests in which the cells to be engineered showed evidence of a characteristic, or marker, known as SSE...

Experimental gene therapy 'abolishes' arthritis pain and lessens joint damage

....S. Food and Drug Administration for permission to begin human trials next year. Nearly everyone aged 65 or older suffers from the pain, swelling and permanent joint damage of osteoarthritis. The most common form of arthritis, it develops over time following initial joint injuries or just as a result of a...

Detecting cold, feeling pain: Study reveals why menthol feels fresh

..." Julius says, "how do you detect these stimuli to begin with" How do your sensory nerve endings do this to begin with" And what are the biochemical and biophysical mechanisms that account for this"" All three r...

Mice with a migraine show signs of brain damage

...rons. The team observed that nerve cells swell and begin to disintegrate, with neurons shedding important connections known as dendritic spines ?the tiny extensions of an individual neuron’s body that usually number in the thousands within a synapse. Mice in the grasp of a migraine lost up to three-quarter...

How to steer a moving cell

...ulated and allow cells which are usually static to begin migrating. The researchers hope to fully define the protein components of the compass to gain a better understanding of what directs cell migration or, in the case of cancer cells and inflammation, cause cells to migrate where they normally woul...

Students invent protective pouch to enhance cell therapy

... provisional patent. Animal testing is expected to begin this summer. If it is successful, human trials would follow. "It’s very impressive," said Aravind Arepally, an interventional radiologist who served as the project’s other sponsor. "We’re basically creating a small bio-reactor inside the vein to...

Scientists identify prion's infectious secret

... "These findings provide a new framework for us to begin exploring properties of prion biology that, up until now, have proven difficult to investigate," says Whitehead Member and MIT Professor of Biology Susan Lindquist, senior author on the paper, which will appear in the May 9 online issue of Nature. ...

Study shows continued success for new HPV vaccine against virus responsible for cervical cancer

...ich encourages females eligible for the vaccine to begin their vaccination series of three shots over six months and to continue seeing their doctor for regular checkups and screenings. ...

Dealing deadly cancers a knockout punch

...linical trials with Reolysin which are expected to begin in 2007, including a Phase II melanoma trial and a Phase I/II ovarian cancer trial. "It is hoped that the trials will clearly show that Reolysin alone or in combination with either radiation or chemotherapy can stop or reverse the growth of advanc...

Sleepless for science: Flies show link between sleep, immune system in Stanford study

...ad thing." Building on their findings, they can begin to answer these questions. Shirasu-Hiza will be testing mutant flies with other circadian rhythm genes missing. They hope their work inspires researchers who work on vertebrates to explore the molecular underpinnings of the interaction between sle...

Thymus transplants gives hope to babies with fatal immune disease

...aby's thigh, where they attract a blood supply and begin to act like a thymus gland. Within three to four months, mature T cells begin to appear in the bloodstream. The latest Duke analysis followed the first 54 children with DiGeor...

Dinosaur hearing, listening to muscle noise, quieter cubicles

... will not be alerted to their presence. When they begin feeding, they become more vocal. Learning more about the foraging behavior of transients is important for understanding their important roles in the marine ecosystem. To increase opportunities for observing the whales, Kelly Newman ( k.newman@sfos.u...

Chemical maps hint at drug's effects on schizophrenia

...to earlier diagnosis of schizophrenia. It may also begin to explain what makes some people more susceptible...chiatry and senior study investigator. "Now we can begin to develop better medicines that target the specific metabolites important for the disease but not t...

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